Xihui Lin

TL;DR: It is suggested that intensified treatment of genomically aggressive localized prostate cancer may improve cure rates and numerous molecular aberrations were prognostic for disease recurrence, including several DNA methylation events, and a signature comprised of these aberration outperformed well-described prognostic biomarkers.

TL;DR: 50 independent methods were developed to predict overall survival and were evaluated through the DREAM challenge, and the top performer was based on an ensemble of penalised Cox regression models (ePCR), which uniquely identified predictive interaction effects with immune biomarkers and markers of hepatic and renal function.

TL;DR: A meta‐analysis of the state of the art in predicting cognitive outcomes in Alzheimer's disease based on high dimensional, publicly available genetic and structural imaging data failed to identify a meaningful predictor developed from either data modality.

TL;DR: PD‐L1 expression was associated with nonepithelioid MPM, poor clinical outcome, and increased immunological infiltrates and copy number aberrations.

TL;DR: In patients with N2 disease, strong PD-L1 expression was associated with significantly improved disease-free (DFS) and overall survival (OS) in multivariate analysis, and the observed survival benefit in N1 disease requires confirmation.