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Ya-Long Guo
Researcher at Chinese Academy of Sciences
Publications - 53
Citations - 3697
Ya-Long Guo is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 23, co-authored 39 publications receiving 2957 citations. Previous affiliations of Ya-Long Guo include Max Planck Society.
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Journal ArticleDOI
The Arabidopsis lyrata genome sequence and the basis of rapid genome size change
Tina T. Hu,Pedro Pattyn,E. G. Bakker,Jun Cao,Jan Fang Cheng,Richard M. Clark,Noah Fahlgren,Jeffrey A. Fawcett,Jane Grimwood,Heidrun Gundlach,Georg Haberer,Jesse D. Hollister,Stephan Ossowski,Robert P. Ottilar,Asaf Salamov,Korbinian Schneeberger,Manuel Spannagl,Xi-Mo Wang,Liang Yang,Mikhail E. Nasrallah,Joy Bergelson,James C. Carrington,Brandon S. Gaut,Jeremy Schmutz,Klaus F. X. Mayer,Yves Van de Peer,Igor V. Grigoriev,Magnus Nordborg,Magnus Nordborg,Detlef Weigel,Ya-Long Guo +30 more
TL;DR: The 207-Mb genome sequence of the North American Arabidopsis lyrata strain MN47, based on 8.3× dideoxy sequence coverage, is reported, indicating pervasive selection for a smaller genome in this outcrossing species.
Journal ArticleDOI
The Capsella rubella genome and the genomic consequences of rapid mating system evolution
Tanja Slotte,Tanja Slotte,Khaled M. Hazzouri,Khaled M. Hazzouri,J. Arvid Ågren,Daniel Koenig,Florian Maumus,Ya-Long Guo,Kim A. Steige,Adrian E. Platts,Juan S. Escobar,L. Killian Newman,Wei Wang,Terezie Mandáková,Emilio Vello,Lisa M. Smith,Stefan R. Henz,Joshua G. Steffen,Joshua G. Steffen,Shohei Takuno,Shohei Takuno,Yaniv Brandvain,Graham Coop,Peter Andolfatto,Tina T. Hu,Mathieu Blanchette,Richard M. Clark,Hadi Quesneville,Magnus Nordborg,Brandon S. Gaut,Martin A. Lysak,Jerry Jenkins,Jane Grimwood,Jarrod Chapman,Simon E. Prochnik,Shengqiang Shu,Daniel S. Rokhsar,Daniel S. Rokhsar,Jeremy Schmutz,Detlef Weigel,Stephen I. Wright +40 more
TL;DR: The transition to selfing may be typified by parallel shifts in gene expression, along with a measurable reduction of purifying selection, similar to that seen in Arabidopsis, which self fertilization evolved about 1 million years ago.
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Transposable elements and small RNAs contribute to gene expression divergence between Arabidopsis thaliana and Arabidopsis lyrata
TL;DR: It is shown that transposable elements—particularly siRNA-targeted TEs—are associated with reduced gene expression within both species and also with gene expression differences between orthologs, and that A. lyrata TEs are targeted by a lower fraction of uniquely matching siRNAs, which are associated with more effective silencing of TE expression.
Journal ArticleDOI
Recent speciation of Capsella rubella from Capsella grandiflora, associated with loss of self-incompatibility and an extreme bottleneck
Ya-Long Guo,Jesper Bechsgaard,Tanja Slotte,Barbara Neuffer,Martin Lascoux,Detlef Weigel,Mikkel H. Schierup +6 more
TL;DR: Comparison of nucleotide diversity patterns of the 2 species found that C. rubella has only 1 or 2 alleles at most loci, suggesting that it originated through an extreme population bottleneck, and suggests that this species will be an interesting model to understand divergence and adaptation, starting from very limited standing genetic variation.
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Genome-Wide Comparison of Nucleotide-Binding Site-Leucine-Rich Repeat-Encoding Genes in Arabidopsis
TL;DR: This study compared the NB-LRR gene complement of the selfer Arabidopsis thaliana and its outcrossing close relativeArabidopsis lyrata to show a clearly positive relationship between interspecific divergence and intraspecific polymorphisms.