Yechiel Friedlander

TL;DR: SNPs at nine loci were reproducibly associated with myocardial infarction, but tests of common and rare CNVs failed to identify additional associations with my Cardiovascular Infarction risk.

TL;DR: It is shown that common variation in n-3 metabolic pathway genes and in GCKR influences plasma phospholipid levels of n- 3 PUFAs in populations of European ancestry and, for FADS1, in other ancestries.

TL;DR: Family history of MI or PCA is positively associated with the risk of primary cardiac arrest, and this association is mostly independent of familial aggregation of other common risk factors.

TL;DR: A prospective study in an independent population cohort revealed significant hypomethylation of young individuals that later progressed to T2DM, relative to the individuals who stayed healthy, and suggests a novel mechanism by which early-onset, inter-individual methylation variation at isolated non-promoter genomic sites predisposes to T1DM.

TL;DR: Findings suggest a potential role of familial factors related to both MI and SD in PCA, and stronger findings for a familial patterning of PCA were noted for early onset disease in cases and their relatives.