P
Patrick Linsel-Nitschke
Researcher at University of Lübeck
Publications - 39
Citations - 5599
Patrick Linsel-Nitschke is an academic researcher from University of Lübeck. The author has contributed to research in topics: Population & Single-nucleotide polymorphism. The author has an hindex of 27, co-authored 39 publications receiving 5307 citations. Previous affiliations of Patrick Linsel-Nitschke include Columbia University.
Papers
More filters
Journal ArticleDOI
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
Sekar Kathiresan,Benjamin F. Voight,Shaun Purcell,Kiran Musunuru,Diego Ardissino,Pier Mannuccio Mannucci,Sonia S. Anand,James C. Engert,Nilesh J. Samani,Heribert Schunkert,Jeanette Erdmann,Muredach P. Reilly,Daniel J. Rader,Thomas M. Morgan,John A. Spertus,Monika Stoll,Domenico Girelli,Pascal P. McKeown,Christopher Patterson,David S. Siscovick,Christopher J. O'Donnell,Roberto Elosua,Leena Peltonen,Veikko Salomaa,Stephen M. Schwartz,Olle Melander,David Altshuler,Pier Angelica Merlini,Carlo Berzuini,Luisa Bernardinelli,Flora Peyvandi,Marco Tubaro,Patrizia Celli,Maurizio Ferrario,Raffaela Fetiveau,Nicola Marziliano,Giorgio Casari,Michele Galli,Flavio Ribichini,Marco Rossi,Francesco Bernardi,Pietro Zonzin,Alberto Piazza,Jean Yee,Yechiel Friedlander,Jaume Marrugat,Gavin Lucas,Isaac Subirana,Joan Sala,Rafael Ramos,James B. Meigs,Gordon H. Williams,David M. Nathan,Calum A. MacRae,Aki S. Havulinna,Göran Berglund,Joel N. Hirschhorn,Rosanna Asselta,Stefano Duga,Marta Spreafico,Mark J. Daly,James Nemesh,Joshua M. Korn,Steven A. McCarroll,Aarti Surti,Candace Guiducci,Lauren Gianniny,Daniel B. Mirel,Melissa Parkin,Noël P. Burtt,Stacey Gabriel,John R. Thompson,Peter S. Braund,Benjamin J. Wright,Anthony J. Balmforth,Stephen G. Ball,Alistair S. Hall,Patrick Linsel-Nitschke,Wolfgang Lieb,Andreas Ziegler,Inke R. König,Christian Hengstenberg,Marcus Fischer,Klaus Stark,Anika Grosshennig,Michael Preuss,H-Erich Wichmann,Stefan Schreiber,Willem H. Ouwehand,Panos Deloukas,Michael Scholz,François Cambien,Mingyao Li,Zhen Chen,Robert L. Wilensky,William H. Matthai,Atif Qasim,Hakon Hakonarson,Joe Devaney,Mary-Susan Burnett,Augusto D. Pichard,Kenneth M. Kent,Lowell F. Satler,Joseph M. Lindsay,Ron Waksman,Stephen E. Epstein,Thomas Scheffold,Klaus Berger,Andreas Huge,Nicola Martinelli,Oliviero Olivieri,Roberto Corrocher,Hilma Holm,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Kari Stefansson,Ron Do,Changchun Xie,David S. Siscovick +118 more
TL;DR: SNPs at nine loci were reproducibly associated with myocardial infarction, but tests of common and rare CNVs failed to identify additional associations with my Cardiovascular Infarction risk.
Journal ArticleDOI
New susceptibility locus for coronary artery disease on chromosome 3q22.3
Jeanette Erdmann,Anika Großhennig,Peter S. Braund,Inke R. König,Christian Hengstenberg,Alistair S. Hall,Patrick Linsel-Nitschke,Sekar Kathiresan,Ben J Wright,David-Alexandre Trégouët,François Cambien,Petra Bruse,Zouhair Aherrahrou,Arnika Kathleen Wagner,Klaus Stark,Stephen M. Schwartz,Veikko Salomaa,Roberto Elosua,Olle Melander,Benjamin F. Voight,Christopher J. O'Donnell,Leena Peltonen,David S. Siscovick,David Altshuler,Piera Angelica Merlini,Flora Peyvandi,Luisa Bernardinelli,Luisa Bernardinelli,Diego Ardissino,Arne Schillert,Stefan Blankenberg,Tanja Zeller,Philipp S. Wild,Daniel F Schwarz,Laurence Tiret,Claire Perret,Stefan Schreiber,Nour Eddine El Mokhtari,Arne Schäfer,Winfried März,Winfried März,Winfried März,Wilfried Renner,Peter Bugert,Harald Klüter,Jürgen Schrezenmeir,Diana Rubin,Stephen G. Ball,Anthony J. Balmforth,H-Erich Wichmann,Thomas Meitinger,Marcus Fischer,Christa Meisinger,Jens Baumert,Annette Peters,Willem H. Ouwehand,Panos Deloukas,John R. Thompson,Andreas Ziegler,Nilesh J. Samani,Heribert Schunkert +60 more
TL;DR: A three-stage analysis of genome-wide SNP data in 1,222 German individuals with myocardial infarction and 1,298 controls is presented and suggestive association with a locus on 12q24.31 near HNF1A-C12orf43 is identified.
Journal ArticleDOI
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease
David-Alexandre Trégouët,Inke R. König,Jeanette Erdmann,Alexandru Munteanu,Peter S. Braund,Alistair S. Hall,Anika Großhennig,Patrick Linsel-Nitschke,Claire Perret,Maylis DeSuremain,Thomas Meitinger,Ben J Wright,Michael Preuss,Anthony J. Balmforth,Stephen G. Ball,Christa Meisinger,Cécile Germain,Alun Evans,Dominique Arveiler,Gérald Luc,Jean-Bernard Ruidavets,Caroline Morrison,Pim van der Harst,Stefan Schreiber,Katharina Neureuther,Arne Schäfer,Peter Bugert,Nour Eddine El Mokhtari,Jürgen Schrezenmeir,Klaus Stark,Diana Rubin,H-Erich Wichmann,Christian Hengstenberg,Willem H. Ouwehand,Andreas Ziegler,Laurence Tiret,John R. Thompson,François Cambien,Heribert Schunkert,Nilesh J. Samani +39 more
TL;DR: The SLC22A3-LPAL2-LPA gene cluster is identified as a strong susceptibility locus for coronary artery disease through a genome-wide haplotype association (GWHA) study and may have wide utility for analyzing GWA data for other complex traits.
Journal ArticleDOI
HDL as a target in the treatment of atherosclerotic cardiovascular disease
TL;DR: Several strategies that have recently emerged to increase levels of HDL cholesterol to treat cardiovascular disease are discussed, including nuclear receptor modulation, inhibition of cholesteryl ester transfer protein and infusion of apolipoprotein/phospholipid complexes.
Journal ArticleDOI
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
Cristian Pattaro,Alexander Teumer,Mathias Gorski,Audrey Y. Chu,Man Li,Vladan Mijatovic,Maija K. Garnaas,Adrienne Tin,Rossella Sorice,Yong Li,Daniel Taliun,Matthias Olden,Meredith C. Foster,Qiong Yang,Ming-Huei Chen,Tune H. Pers,Tune H. Pers,Andrew D. Johnson,Yi-An Ko,Christian Fuchsberger,Bamidele O. Tayo,Mike A. Nalls,Mary F. Feitosa,Aaron Isaacs,Abbas Dehghan,Pio D'Adamo,Adebowale Adeyemo,Aida Karina Dieffenbach,Alan B. Zonderman,Ilja M. Nolte,Peter J. van der Most,Alan F. Wright,Alan R. Shuldiner,Alan R. Shuldiner,Alanna C. Morrison,Albert Hofman,Albert V. Smith,Albert W. Dreisbach,Andre Franke,André G. Uitterlinden,Andres Metspalu,Anke Tönjes,Antonio Lupo,Antonietta Robino,Åsa Johansson,Ayse Demirkan,Barbara Kollerits,Barry I. Freedman,Belen Ponte,Ben A. Oostra,Bernhard Paulweber,Bernhard K. Krämer,Braxton D. Mitchell,Braxton D. Mitchell,Brendan M. Buckley,Carmen A. Peralta,Caroline Hayward,Catherine Helmer,Catherine Helmer,Charles N. Rotimi,Christian M. Shaffer,Christian Müller,Cinzia Sala,Cornelia M. van Duijn,Aude Saint-Pierre,Daniel Ackermann,Daniel Shriner,Daniela Ruggiero,Daniela Toniolo,Yingchang Lu,Daniele Cusi,Darina Czamara,David Ellinghaus,David S. Siscovick,Douglas M. Ruderfer,Christian Gieger,Harald Grallert,Elena Rochtchina,Elizabeth J. Atkinson,Elizabeth G. Holliday,Eric Boerwinkle,Erika Salvi,Erwin P. Bottinger,Federico Murgia,Fernando Rivadeneira,Florian Ernst,Florian Kronenberg,Frank B. Hu,Gerjan Navis,Gary C. Curhan,G. Ehret,Georg Homuth,Stefan Coassin,Gian Andri Thun,Gian Andri Thun,Giorgio Pistis,Giovanni Gambaro,Giovanni Malerba,Grant W. Montgomery,Gudny Eiriksdottir,Gunnar Jacobs,Guo Li,H.-Erich Wichmann,Harry Campbell,Helena Schmidt,Henri Wallaschofski,Henry Völzke,Hermann Brenner,Heyo K. Kroemer,Holly Kramer,Honghuang Lin,I. Mateo Leach,Ian Ford,Idris Guessous,Idris Guessous,Idris Guessous,Igor Rudan,Inga Prokopenko,Ingrid B. Borecki,Iris M. Heid,Ivana Kolcic,Ivana Persico,J. Wouter Jukema,James F. Wilson,Janine F. Felix,Jasmin Divers,Jean-Charles Lambert,Jeanette M. Stafford,Jean-Michel Gaspoz,Jennifer A. Smith,Jessica D. Faul,Jie Jin Wang,Jingzhong Ding,Joel N. Hirschhorn,Joel N. Hirschhorn,John Attia,John Attia,John Whitfield,John Chalmers,J. Viikari,Josef Coresh,Joshua C. Denny,Juha Karjalainen,Jyotika K. Fernandes,Karlhans Endlich,Katja Butterbach,Keith L. Keene,Kurt Lohman,Laura Portas,Lenore J. Launer,Leo-Pekka Lyytikäinen,Loic Yengo,Loic Yengo,Loic Yengo,Lude Franke,Luigi Ferrucci,Lynda M. Rose,Lyudmyla Kedenko,Madhumathi Rao,Maksim Struchalin,Marcus E. Kleber,Margherita Cavalieri,Margot Haun,Marilyn C. Cornelis,Marina Ciullo,Mario Pirastu,Mariza de Andrade,Mark McEvoy,Mark Woodward,Martin Adam,Martin Adam,Massimiliano Cocca,Matthias Nauck,Medea Imboden,Medea Imboden,Melanie Waldenberger,Menno Pruijm,Marie Metzger,Michael Stumvoll,Michele K. Evans,Michèle M. Sale,Mika Kähönen,Mladen Boban,Murielle Bochud,Myriam Rheinberger,Niek Verweij,Nabila Bouatia-Naji,Nabila Bouatia-Naji,Nicholas G. Martin,Nicholas G. Martin,Nicholas D. Hastie,Nicole Probst-Hensch,Nicole Probst-Hensch,Nicole Soranzo,Olivier Devuyst,Olli T. Raitakari,Omri Gottesman,Oscar H. Franco,Ozren Polasek,Paolo Gasparini,Patricia B. Munroe,Paul M. Ridker,Paul Mitchell,Paul Muntner,Christa Meisinger,Johannes H. Smit,Gonçalo R. Abecasis,Linda S. Adair,Myriam Alexander,David Altshuler,Najaf Amin,Dan E. Arking,Pankaj Arora,Yurii S. Aulchenko,Stephan J. L. Bakker,Stefania Bandinelli,Inês Barroso,Jacques S. Beckmann,John Beilby,Richard N. Bergman,Sven Bergmann,Joshua C. Bis,Michael Boehnke,Lori L. Bonnycastle,Stefan R. Bornstein,Michiel L. Bots,Jennifer L. Bragg-Gresham,Stefan Martin Brand,Eva Brand,Peter S. Braund,Morris J. Brown,Paul Burton,Juan P. Casas,Mark J. Caulfield,Aravinda Chakravarti,John C. Chambers,Giriraj R. Chandak,Yen Pei C. Chang,Fadi J. Charchar,Nish Chaturvedi,Yoon Shin Cho,Robert Clarke,Francis S. Collins,Rory Collins,John M. C. Connell,Jackie A. Cooper,Mark E. Cooper,Richard S. Cooper,Anna Maria Corsi,Marcus Dörr,Santosh Dahgam,John Danesh,George Davey Smith,Ian N. M. Day,Panos Deloukas,Matthew Denniff,Anna F. Dominiczak,Yanbin Dong,Ayo P. Doumatey,Paul Elliott,Roberto Elosua,Jeanette Erdmann,Susana Eyheramendy,Martin Farrall,Cristiano Fava,Terrence Forrester,F. Gerald R. Fowkes,Ervin R. Fox,Timothy M. Frayling,Pilar Galan,Santhi K. Ganesh,Melissa Garcia,Tom R. Gaunt,Nicole L. Glazer,Min Jin Go,Anuj Goel,Jürgen Grässler,Diederick E. Grobbee,Leif Groop,Simonetta Guarrera,Xiuqing Guo,David Hadley,Anders Hamsten,Bok Ghee Han,Rebecca Hardy,Anna-Liisa Hartikainen,Simon Heath,Susan R. Heckbert,Bo Hedblad,Serge Hercberg,Dena G. Hernandez,Andrew A. Hicks,Gina Hilton,Aroon D. Hingorani,Judith A. Hoffman Bolton,Jemma C. Hopewell,Philip Howard,Steve E. Humphries,Steven C. Hunt,Kristian Hveem,M. Arfan Ikram,Muhammad Islam,Naoharu Iwai,Marjo-Riitta Järvelin,Anne U. Jackson,Tazeen H. Jafar,C. S. Janipalli,Toby Johnson,Sekar Kathiresan,Kay-Tee Khaw,Hyung Lae Kim,Sanjay Kinra,Yoshikuni Kita,Mika Kivimäki,Jaspal S. Kooner,M. J.Kranthi Kumar,Diana Kuh,Smita R. Kulkarni,Meena Kumari,Johanna Kuusisto,Tatiana Kuznetsova,Markku Laakso,Maris Laan,Jaana Laitinen,Edward G. Lakatta,Carl D. Langefeld,Martin G. Larson,Mark Lathrop,Debbie A Lawlor,Robert W. Lawrence,Jong-Young Lee,Nanette R. Lee,Daniel Levy,Yali Li,Will Longstreth,Jian'an Luan,Gavin Lucas,Barbara Ludwig,Massimo Mangino,K. Radha Mani,Michael Marmot,Francesco U.S. Mattace-Raso,Giuseppe Matullo,Wendy L. McArdle,Colin A. McKenzie,Thomas Meitinger,Olle Melander,Pierre Meneton,James F. Meschia,Tetsuro Miki,Yuri Milaneschi,Karen L. Mohlke,Vincent Mooser,Mario A. Morken,Richard W Morris,Thomas H. Mosley,Samer S. Najjar,Narisu Narisu,Christopher Newton-Cheh,Khanh-Dung H. Nguyen,Peter M. Nilsson,Fredrik Nyberg,Christopher J. O'Donnell,Toshio Ogihara,Takayoshi Ohkubo,Tomonori Okamura,Rick Twee-Hee Ong,Halit Ongen,N. Charlotte Onland-Moret,Paul F. O'Reilly,Elin Org,Marco Orrù,Walter Palmas,Jutta Palmen,Lyle J. Palmer,Nicholette D. Palmer,Alex Parker,John F. Peden,Leena Peltonen,Markus Perola,Vasyl Pihur,Carl G. P. Platou,Andrew S. Plump,Dorairajan Prabhakaran,Bruce M. Psaty,Leslie J. Raffel,Dabeeru C. Rao,Asif Rasheed,Fulvio Ricceri,Kenneth Rice,Annika Rosengren,Jerome I. Rotter,Megan E. Rudock,Siim Sõber,Tunde Salako,Danish Saleheen,Veikko Salomaa,Nilesh J. Samani,Steven M. Schwartz,Peter Schwarz,Laura J. Scott,James Scott,Angelo Scuteri,Joban Sehmi,Mark Seielstad,Sudha Seshadri,Pankaj Sharma,Sue Shaw-Hawkins,Gang Shi,Nick Shrine,Eric J.G. Sijbrands,Xueling Sim,Andrew B. Singleton,Marketa Sjögren,Nicholas L. Smith,María Soler Artigas,Tim D. Spector,Jan A. Staessen,Alena Stančáková,Nanette I. Steinle,David P. Strachan,Heather M. Stringham,Yan V. Sun,Amy J. Swift,Yasuharu Tabara,E. Shyong Tai,Philippa J. Talmud,Andrew M. Taylor,Janoš Terzić,Dag S. Thelle,Martin D. Tobin,Maciej Tomaszewski,Vikal Tripathy,Jaakko Tuomilehto,Ioanna Tzoulaki,Manuela Uda,Hirotsugu Ueshima,Cuno S. P. M. Uiterwaal,Satoshi Umemura,Pim van der Harst,Yvonne T. van der Schouw,Wiek H. van Gilst,Erkki Vartiainen,Ramachandran S. Vasan,Gudrun Veldre,Germaine C. Verwoert,Margus Viigimaa,D. G. Vinay,Paolo Vineis,Benjamin F. Voight,Peter Vollenweider,Lynne E. Wagenknecht,Louise V. Wain,Xiaoling Wang,Thomas J. Wang,Nicholas J. Wareham,Hugh Watkins,Alan B. Weder,Peter H. Whincup,Kerri L. Wiggins,Jacqueline C.M. Witteman,Andrew Wong,Ying Wu,Chittaranjan S. Yajnik,Jie Yao,J. H. Young,Diana Zelenika,Guangju Zhai,Weihua Zhang,Feng Zhang,Jing Hua Zhao,Haidong Zhu,Xiaofeng Zhu,Paavo Zitting,Ewa Zukowska-Szczechowska,Yukinori Okada,Jer-Yuarn Wu,Jer-Yuarn Wu,Dongfeng Gu,Fumihiko Takeuchi,Atsushi Takahashi,Shiro Maeda,Tatsuhiko Tsunoda,Peng Chen,Su Chi Lim,Su Chi Lim,Tien Yin Wong,Tien Yin Wong,Tien Yin Wong,Jianjun Liu,Terri L. Young,Tin Aung,Tin Aung,Yik Ying Teo,Yik Ying Teo,Young-Jin Kim,Daehee Kang,Chien-Hsiun Chen,Chien-Hsiun Chen,Fuu Jen Tsai,Li Ching Chang,S. J.Cathy Fann,Hao Mei,James E. Hixson,Shufeng Chen,Tomohiro Katsuya,Masato Isono,Eva Albrecht,Kazuhiko Yamamoto,Michiaki Kubo,Yusuke Nakamura,Naoyuki Kamatani,Norihiro Kato,Jiang He,Yuan-Tsong Chen,Toshihiro Tanaka,Muredach P. Reilly,Heribert Schunkert,Heribert Schunkert,Themistocles L. Assimes,Alistair S. Hall,Christian Hengstenberg,Inke R. König,Reijo Laaksonen,Ruth McPherson,John R. Thompson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Andreas Ziegler,Devin Absher,Li Chen,L. Adrienne Cupples,L. Adrienne Cupples,Eran Halperin,Eran Halperin,Mingyao Li,Kiran Musunuru,Kiran Musunuru,Michael Preuss,Arne Schillert,Gudmar Thorleifsson,George A. Wells,Hilma Holm,Robert Roberts,Alexandre F.R. Stewart,Stephen P. Fortmann,Alan S. Go,Mark A. Hlatky,Carlos Iribarren,Joshua W. Knowles,Richard M. Myers,Thomas Quertermous,S. Sidney,Neil Risch,Hua Tang,Stefan Blankenberg,Renate B. Schnabel,C. Sinning,Karl J. Lackner,Laurence Tiret,Viviane Nicaud,François Cambien,Christoph Bickel,Hans J. Rupprecht,Claire Perret,Carole Proust,Thomas Münzel,Maja Barbalić,Ida Yii Der Chen,Serkalem Demissie-Banjaw,Serkalem Demissie-Banjaw,Aaron R. Folsom,Thomas Lumley,Kristin D. Marciante,Kent D. Taylor,Kelly A. Volcik,Solveig Gretarsdottir,Jeffrey R. Gulcher,Augustine Kong,Kari Stefansson,Kari Stefansson,Gudmundur Thorgeirsson,Karl Andersen,Marcus Fischer,Anika Grosshennig,Patrick Linsel-Nitschke,Klaus Stark,Stefan Schreiber,Zouhair Aherrahrou,Petra Bruse,Angela Doering,Norman Klopp,Patrick Diemert,Christina Loley,Anja Medack,Janja Nahrstedt,Annette Peters,Arnika Kathleen Wagner,Christina Willenborg,Bernhard O. Böhm,Harald Dobnig,Tanja B. Grammer,Michael M. Hoffmann,Andreas Meinitzer,Bernhard R. Winkelmann,Stefan Pilz,Wilfried Renner,Hubert Scharnagl,Tatjana Stojakovic,Andreas Tomaschitz,Karl Winkler,Candace Guiducci,Noël P. Burtt,Stacey Gabriel,Sonny Dandona,Olga Jarinova,Liming Qu,Robert L. Wilensky,William H. Matthai,Hakon Hakonarson,Joe Devaney,Mary Susan Burnett,Augusto D. Pichard,Kenneth M. Kent,Lowell F. Satler,Joseph M. Lindsay,Ron Waksman,Christopher W. Knouff,Dawn M. Waterworth,M Walker,Stephen E. Epstein,Daniel J. Rader,Christopher P. Nelson,Benjamin J. Wright,Anthony J. Balmforth,Stephen G. Ball,Laura R. Loehr,Laura R. Loehr,Wayne D. Rosamond,Emelia J. Benjamin,Talin Haritunians,David Couper,Joanne M. Murabito,Ying A. Wang,Bruno H. Stricker,Patricia P. Chang,James T. Willerson,James T. Willerson,Stephan B. Felix,Norbert Watzinger,Jayashri Aragam,Robert Zweiker,Lars Lind,Richard J. Rodeheffer,Karin Halina Greiser,Jaap W. Deckers,Jan Stritzke,Erik Ingelsson,Iftikhar J. Kullo,Johannes Haerting,Thorsten Reffelmann,Margaret M. Redfield,Karl Werdan,Gary F. Mitchell,Donna K. Arnett,John S. Gottdiener,Maria Blettner,Nele Friedrich,Peter Kovacs,Philipp S. Wild,Philippe Froguel,Philippe Froguel,Philippe Froguel,Rainer Rettig,Reedik Mägi,Reiner Biffar,Reinhold Schmidt,Rita P.S. Middelberg,Robert J. Carroll,Brenda W.J.H. Penninx,Rodney J. Scott,Ronit Katz,Sanaz Sedaghat,Sarah H. Wild,Sharon L.R. Kardia,Sheila Ulivi,Shih-Jen Hwang,Stefan Enroth,Stefan Kloiber,Stella Trompet,Bénédicte Stengel,Stephen Hancock,Stephen Turner,Sylvia E. Rosas,Sylvia Stracke,Sylvia Stracke,Tamara B. Harris,Tanja Zeller,Tatijana Zemunik,Terho Lehtimäki,Thomas Illig,Thor Aspelund,Tiit Nikopensius,Tõnu Esko,Tõnu Esko,Toshiko Tanaka,Ulf Gyllensten,Uwe Völker,Valur Emilsson,Veronique Vitart,Ville Aalto,Vilmundur Gudnason,Vincent Chouraki,Wei-Min Chen,Wilmar Igl,Winfried März,Wolfgang Koenig,Wolfgang Lieb,Ruth J. F. Loos,Yongmei Liu,Harold Snieder,Peter P. Pramstaller,Afshin Parsa,Jeffrey R. O'Connell,Katalin Susztak,Pavel Hamet,Johanne Tremblay,Ian H. de Boer,Carsten A. Böger,Wolfram Goessling,Daniel I. Chasman,Anna Köttgen,Anna Köttgen,W. H. Linda Kao,Caroline S. Fox,Caroline S. Fox +735 more
TL;DR: A meta-analysis of genome-wide association studies for estimated glomerular filtration rate suggests that genetic determinants of eGFR are mediated largely through direct effects within the kidney and highlight important cell types and biological pathways.