Y
Yu Zhang
Researcher at Ocean University of China
Publications - 35
Citations - 1688
Yu Zhang is an academic researcher from Ocean University of China. The author has contributed to research in topics: Catfish & Genome. The author has an hindex of 18, co-authored 33 publications receiving 1400 citations. Previous affiliations of Yu Zhang include Auburn University & Chinese Academy of Fishery Sciences.
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Journal ArticleDOI
The channel catfish genome sequence provides insights into the evolution of scale formation in teleosts.
Zhanjiang Liu,Shikai Liu,Jun Yao,Lisui Bao,Jiaren Zhang,Yun Li,Chen Jiang,Luyang Sun,Ruijia Wang,Yu Zhang,Tao Zhou,Qifan Zeng,Qiang Fu,Sen Gao,Ning Li,Sergey Koren,Yanliang Jiang,Aleksey V. Zimin,Peng Xu,Adam M. Phillippy,Xin Geng,Lin Song,Fanyue Sun,Chao Li,Xiaozhu Wang,Ailu Chen,Yulin Jin,Zihao Yuan,Yujia Yang,Suxu Tan,Eric Peatman,Jianguo Lu,Zhenkui Qin,Rex A. Dunham,Zhaoxia Li,Tad S. Sonstegard,Jianbin Feng,Roy G. Danzmann,Steven Schroeder,Brian E. Scheffler,Mary V. Duke,Linda L. Ballard,Huseyin Kucuktas,Ludmilla Kaltenboeck,Haixia Liu,Jonathan W. Armbruster,Yangjie Xie,Mona L. Kirby,Yi Tian,Mary Elizabeth Flanagan,Weijie Mu,Geoffrey C. Waldbieser +51 more
TL;DR: A high-quality reference genome sequence of channel catfish is reported, providing evidence that lack of secretory calcium-binding phosphoproteins accounts for the evolutionary loss of scales in catfish and demonstrates the power of comparative subtraction of candidate genes for traits of structural significance.
Journal ArticleDOI
RNA-seq analysis of mucosal immune responses reveals signatures of intestinal barrier disruption and pathogen entry following Edwardsiella ictaluri infection in channel catfish, Ictalurus punctatus.
Chao Li,Yu Zhang,Ruijia Wang,Jianguo Lu,Samiran Nandi,S. Mohanty,Jeffery S. Terhune,Zhanjiang Liu,Eric Peatman +8 more
TL;DR: The results set a foundation for future studies comparing mechanisms of pathogen entry and mucosal immunity across several important catfish pathogens including E. ictaluri, Edwardsiellatarda, Flavobacterium columnare, and virulent atypical Aeromonas hydrophila.
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RNA-Seq reveals expression signatures of genes involved in oxygen transport, protein synthesis, folding, and degradation in response to heat stress in catfish
Shikai Liu,Xiuli Wang,Xiuli Wang,Fanyue Sun,Jiaren Zhang,Jianbin Feng,Hong Liu,K.V. Rajendran,Luyang Sun,Yu Zhang,Yanliang Jiang,Eric Peatman,Ludmilla Kaltenboeck,Huseyin Kucuktas,Zhanjiang Liu +14 more
TL;DR: This is the first RNA-Seq-based expression study in catfish in response to heat stress, and the candidate genes identified should be valuable for further targeted studies on heat tolerance, thereby assisting the development of heat-tolerant catfish lines for aquaculture.
Journal ArticleDOI
Efficient assembly and annotation of the transcriptome of catfish by RNA-Seq analysis of a doubled haploid homozygote
Shikai Liu,Shikai Liu,Yu Zhang,Zunchun Zhou,Geoff Waldbieser,Fanyue Sun,Jianguo Lu,Jiaren Zhang,Yanliang Jiang,Hao Zhang,Xiuli Wang,K.V. Rajendran,Lester H. Khoo,Huseyin Kucuktas,Eric Peatman,Zhanjiang Liu +15 more
TL;DR: The large set of transcripts assembled in this study is the most comprehensive set of genome resources ever developed from catfish, which will provide the much needed resources for functional genome research inCatfish, serving as a reference transcriptome for genome annotation, analysis of gene duplication, gene family structures, and digital gene expression analysis.
Journal ArticleDOI
A genome-wide association study in catfish reveals the presence of functional hubs of related genes within QTLs for columnaris disease resistance
Xin Geng,Jin Sha,Shikai Liu,Lisui Bao,Jiaren Zhang,Ruijia Wang,Jun Yao,Chao Li,Jianbin Feng,Fanyue Sun,Luyang Sun,Chen Jiang,Yu Zhang,Ailu Chen,Rex A. Dunham,Degui Zhi,Zhanjiang Liu +16 more
TL;DR: Four QTLs associated with columnaris resistance in catfish are revealed and many candidate genes on the four associated regions are involved in PI3K pathway that is known to be required by many bacteria for efficient entry into the host.