Ahi Evran University

About: Ahi Evran University is a education organization based out in Kırşehir, Turkey. It is known for research contribution in the topics: Density functional theory & Ab initio. The organization has 842 authors who have published 2270 publications receiving 21904 citations.

Karstic Landscapes and Landforms in Turkey

Abstract: Approximately, 40% of Turkey’s landmass consists of soluble rocks (limestone, dolomite, and gypsum) highly suitable for karstification. While presenting different lithological composition, lithostratigraphic and structural characteristics, these rocks reach in some places up to 4000 m in elevation. Tectonic movements since the middle Miocene have played, together with climate, a major role in the processes of karst development. Several factors intervene in the formation processes and history of the karstic landscapes of Turkey: structural dynamics (mainly extensional tectonics and block faulting) and its spatial distribution, relief rejuvenation responding to the combination of uplift intensity and sea-level changes and the stratigraphic/lithologic context. Resulting from the various combinations possible, there are large-scale differences in the evolution of the karstic landscape within short distances. Consequently, six karstic regions and eleven distinct sub-karstic areas can be identified on the basis of their different morphogenetic and morphometric characteristics.

A case of erythema multiforme major in a patient with COVID 19: The role of corticosteroid treatment.

Abstract: Dear Editor, In December 2019, the cases of pneumonia of unknown etiology were reported in Wuhan city, Hubei province of China. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen, a novel coronavirus, was detected from the lower respiratory tract samples of infected patients, and this virus-caused respiratory tract infection was termed Coronavirus Disease 2019 (COVID-19). The pandemic was declared by World Health Organization on 11 March 2020 and as of 21 May 21 2020, more than 5 million cases and more than 300 thousand deaths were reported. The disease has been reported to show different types of cutaneous findings including urticarial, maculopapular, erythema multiforme-like, varicella-like, purpuric, livedoid, and thrombotic-ischemic lesions. Given the high mortality rate of the disease, prompt and accurate identification of the relevant skin manifestations may play a significant role in the early diagnosis and appropriate management of the entity. A 37-year-old female patient with confirmed COVID-19 pneumonia presented with erythematous targetoid lesions distributed over the ventral and dorsal sides of the hands, and elbows (Figures 1 and 2). There were also painful ulcerations on the lip, tongue, and palate. (Figure 3). The ocular and genital mucosal surfaces were normal. The lesions occurred on the fifth day of COVID-19 treatment, which included hydroxychloroquine (Day 1: 2 × 400 mg, Day 2-4: 2 × 200 mg), azithromycin (Day 1: 1 × 500 mg, Day 2-4: 1 × 250 mg), and oseltamivir (2 × 75 mg for 5 days). The symptoms related to COVID-19 pneumonia started 10 days before the rash. The patient had no previous medical history of a similar eruption. There was also no history of herpetic infection. Complete blood count, biochemical parameters, and serological tests including Herpes simplex virus IgM and IgG, EbsteinBarr virus IgM and IgG, Cytomegalovirus IgM and IgG, HbsAg, Anti HCV vs Mycoplasma IgM vs IgG antibodies were within normal limits. Biopsy was not performed due to the risk of infection. The patient was clinically diagnosed with Erythema multiforme major (EMM) and all medications were stopped. The patient was then started on 40 mg/day oral methylprednisolone tapered by 5 mg every day. Topical anesthetic and antiseptic mouthwashes were also applied. On the eighth day of the treatment, pneumonia and the cutaneous lesions