Belarusian State Medical University

About: Belarusian State Medical University is a education organization based out in Minsk, Belarus. It is known for research contribution in the topics: Population & Medicine. The organization has 536 authors who have published 513 publications receiving 4635 citations.

The importance of exhaled air condensate in assessing the oxidant-antioxidant system in patients with chronic obstructive pulmonary disease.

Abstract: The aim of this study was to investigate the relationship between selected lipid peroxidation products as markers of oxidative stress and antioxidant defense capacity in exhaled air condensate in comparison to blood and COPD severity. We detected that the increase of lipids peroxidation products in exhaled air condensate (less in blood) was accompanied by the reduction of total antioxidant capacity (antiradical activity and ceruloplasmin) according to the severity of COPD. Thus, the level of malondialdehyde significantly increased both in blood and exhaled air condensate in COPD 1 , 2 , 3 (by 24%, 86%, 100% and 58%, 92%, 2,3 times respectively). Antiradical activity level was significantly decreased both in blood and exhaled air condensate in patients with COPD 2 , 3 by 24%, 51% and 23,31% respectively. The results of this study clearly demonstrated the imbalance in oxidant-antioxidant system in advanced COPD.

Determination of the monitor brightness in the investigations of light sensitivity of retina

Abstract: The article describes the principles of a highly sensitive photometer based on modern CCD digital cameras and laptop. The photometer is designed to measure the absolute brightness of the visual objects, which are formed on the screen of the monitor. The examples of the determination of the integrated brightness of R, G, and B pixel elements, of which the image of a visual object is formed for several types of monitors are given. Streszczenie. Artykuł opisuje zasady budowę i zasadę działania bardzo czułego fotometru opracowanego na nowoczesnych wideo kamerach cyfrowych opartych na strukturach CCD i laptopie. Fotometr przeznaczony jest do pomiaru absolutnej jaskrawości obiektów wyświetlanych na ekranie monitora. Dla kilku typów monitorów zostały podane przykłady wyznaczenia zintegrowanej jaskrawości dla wartości R, G i B elementów pikseli, z których formowany jest wizualny obraz obiektu (Wyznaczenie jaskrawości monitorów przy badaniach czułości świetlnej siatkówki).

Rheological changes in the blood and plasma of patients with myocardial ischemia and diabetes mellitus and dysfunction of their endothelium

Abstract: The rheological properties of the whole blood and plasma of patients with myocardial ischemia and diabetes mellitus and of donors have been investigated using a Couette rotational viscosimeter at a temperature of 25°C in the range of rates of shear of 0.5–60 sec−1. The rheological analysis was performed with the use of the Quemada relation. The functional state of the endothelium and some biochemical indices of the blood of these patients were investigated. It is shown that in patients with myocardial ischemia and diabetes mellitus, accompanied by dyslipemia and endocrine disturbances, rheological derangements and endothelial dysfunction develop.

A pilot study to determine the prevalence of HIV in persons presenting for care with selected conditions: preliminary results from the HIV in Europe study.

Abstract: Purpose of the study: A pilot study was initiated in Autumn 2009 to better define which diseases have a HIV prevalence of >0.1 % as HIV testing of populations with a HIV prevalence above this has shown to be cost-effective. The preliminary results are reported here. Methods: A detailed questionnaire was completed for persons presenting with 8 different indicator diseases; sexually transmitted disease (STD), malignant lymphoma (LYM), cervical or anal cancer/dysplasia (CAN), herpes zoster (HER), ongoing mononucleosis-like illness (MON), unexplained leukocytopenia / thrombocytopenia lasting >4 weeks (CYT), and seborrheic dermatitis/exanthema (SEB). Results: 1482 persons have so far been included in the pilot phase by June 2010 from 29 surveys taking place in Austria, Belarus, Belgium, Bosnia, Croatia, Denmark, Germany, Italy, Poland, Spain, Sweden and Ukraine. Selected characteristics of the patients are shown in Figure ​Figure1.1. Almost 40% reported a previous HIV test; this was highest in the STD (59.0%), HEP (47.5%) and SEB (44.2%) groups. Median age was highest in the LYM group (53 years), and youngest in the MON group (24 years). 104 persons (7.7%) reported one of 5 specific HIV-related symptoms in the previous 5 years (mononucleosis, oral candidiasis, herpes zoster, unexplained leukocytopenia/thrombocytopenia or seborrheic dermatitis); these symptoms were highest in the HER (33.3%), SEB (31.1%) and LYM (21.2%) groups. 134 had visited an STD clinic in the previous 5 years including over half of the STD group (56.3%). 152 had been hospitalised in the previous 5 years; the highest proportion was seen in the HEP group (70.3%). Many of the planned surveys have shown difficult to implement because of reluctance towards introducing routine HIV testing among specialists who are not used to/worried about performing an HIV test. A number of persons have tested HIV-positive. Conclusions: The first results of this pilot study demonstrates the potential benefit of guided HIV testing of patients with selected indicator diseases, as a number of persons have been identified to be HIV-positive. A significant proportion of the persons had previously been hospitalised or reported HIV-associated symptoms but had not been tested. Physicians in some specialities are however reluctant to adopt this testing strategy. Supplement: Abstracts of the Tenth International Congress on Drug Therapy in HIV Infection http://www.biomedcentral.com/content/pdf/1758-2652-13-S4-info.pdf Conference: Tenth International Congress on Drug Therapy in HIV Infection 7-11 November 2010 Glasgow, UK (Published: 8 November 2010) doi:10.1186/1758-2652-13-S4-O16 Cite this article as: Sonnerborg et al.: O135. A pilot study to determine the prevalence of HIV in persons presenting for care with selected conditions: preliminary results from the HIV in Europe study. Journal of the International AIDS Society 2010 13(Suppl 4):O16. Full text: PubMed Central: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112828/