Institution
Hungarian Academy of Sciences
Government•Budapest, Hungary•
About: Hungarian Academy of Sciences is a government organization based out in Budapest, Hungary. It is known for research contribution in the topics: Catalysis & Population. The organization has 21510 authors who have published 56712 publications receiving 1612286 citations. The organization is also known as: Magyar Tudományos Akadémia & MTA.
Topics: Catalysis, Population, Adsorption, Ion, Gene
Papers published on a yearly basis
Papers
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TL;DR: It is suggested that HSP17 behaves as an amphitropic protein and plays a dual role, Depending on its membrane or cytosolic location, it may function as a “membrane stabilizing factor” as a member of a multichaperone protein-folding network.
Abstract: The small heat shock proteins (sHSPs) are ubiquitous stress proteins proposed to act as molecular chaperones to prevent irreversible protein denaturation. We characterized the chaperone activity of Synechocystis HSP17 and found that it has not only protein-protective activity, but also a previously unrecognized ability to stabilize lipid membranes. Like other sHSPs, recombinant Synechocystis HSP17 formed stable complexes with denatured malate dehydrogenase and served as a reservoir for the unfolded substrate, transferring it to the DnaK/DnaJ/GrpE and GroEL/ES chaperone network for subsequent refolding. Large unilamellar vesicles made of synthetic and cyanobacterial lipids were found to modulate this refolding process. Investigation of HSP17-lipid interactions revealed a preference for the liquid crystalline phase and resulted in an elevated physical order in model lipid membranes. Direct evidence for the participation of HSP17 in the control of thylakoid membrane physical state in vivo was gained by examining an hsp17(-) deletion mutant compared with the isogenic wild-type hsp17(+) revertant Synechocystis cells. We suggest that, together with GroEL, HSP17 behaves as an amphitropic protein and plays a dual role. Depending on its membrane or cytosolic location, it may function as a "membrane stabilizing factor" as well as a member of a multichaperone protein-folding network. Membrane association of sHSPs could antagonize the heat-induced hyperfluidization of specific membrane domains and thereby serve to preserve structural and functional integrity of biomembranes.
264 citations
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TL;DR: It is shown that, in Arabidopsis thaliana, Pro biosynthesis can be activated by incompatible plant-pathogen interactions triggering a hypersensitive response (HR), and Pro content and AtP5CS2 expression were enhanced by ROS in wild-type plants, suggesting that ROS may function as an intermediate signal in AtP 5CS2-mediated Pro accumulation.
Abstract: Accumulation of free L-proline (Pro) is a typical stress response incited by osmotic injuries in plants and microorganisms. Although the protective role of Pro in osmotic stress is not well understood, it is thought to function as compatible osmolyte or as a scavenger of reactive oxygen species (ROS). Here we show that, in Arabidopsis thaliana, Pro biosynthesis can be activated by incompatible plant—pathogen interactions triggering a hypersensitive response (HR). Pro accumulates in leaf tissues treated with Pseudomonas syringae pv. tomato avirulent strains (avrRpt2 and avrRpm1) but remains unchanged in leaves infected with isogenic virulent bacteria. Incompatible interactions lead to transcriptional activation of AtP5CS2, but not AtP5CS1, encoding the rate limiting enzyme in Pro biosynthesis pyrroline-5-carboxylate synthase (P5CS). AtP5CS2:GUS and AtP5CS2:LUC transgenes were induced inside and around the HR lesions produced by avirulent Pseudomonas spp. in transgenic plants. Pro accumulation was faster an...
263 citations
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University of Helsinki1, Finnish Meteorological Institute2, University of Tartu3, Meteor4, Hungarian Academy of Sciences5, Netherlands Organisation for Applied Scientific Research6, Royal Netherlands Meteorological Institute7, University of Crete8, National University of Ireland, Galway9, Lund University10, Leibniz Association11, Blaise Pascal University12, University of Grenoble13, Paul Scherrer Institute14, University of Eastern Finland15, Stockholm University16
TL;DR: In this paper, the authors present comprehensive results on continuous atmospheric cluster and particle measurements in the size range ∼1-42 nm within the European Integrated project on Aerosol Cloud Climate and Air Quality interactions (EUCAARI) project.
Abstract: We present comprehensive results on continuous atmospheric cluster and particle measurements in the size range ∼1-42 nm within the European Integrated project on Aerosol Cloud Climate and Air Quality interactions (EUCAARI) project. We focused on characterizing the spatial and temporal variation of new particle formation events and relevant particle formation parameters across Europe. Different types of air ion and cluster mobility spectrometers were deployed at 12 field sites across Europe from March 2008 to May 2009. The measurements were conducted in a wide variety of environments, including coastal and continental locations as well as sites at different altitudes (both in the boundary layer and the free troposphere). New particle formation events were detected at all of the 12 field sites during the year-long measurement period. From the data, nucleation and growth rates of newly formed particles were determined for each environment. In a case of parallel ion and neutral cluster measurements, we could also estimate the relative contribution of ion-induced and neutral nucleation to the total particle formation. The formation rates of charged particles at 2 nm accounted for 1-30% of the corresponding total particle formation rates. As a significant new result, we found out that the total particle formation rate varied much more between the different sites than the formation rate of charged particles. This work presents, so far, the most comprehensive effort to experimentally characterize nucleation and growth of atmospheric molecular clusters and nanoparticles at ground-based observation sites on a continental scale. © Author(s) 2010.
263 citations
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Goethe University Frankfurt1, Joint Institute for Nuclear Research2, Hungarian Academy of Sciences3, Polish Academy of Sciences4, University of Marburg5, Charles University in Prague6, Université libre de Bruxelles7, Comenius University in Bratislava8, CERN9, Lawrence Berkeley National Laboratory10, University of Washington11, University of Toulouse12, Max Planck Society13, Eötvös Loránd University14, GSI Helmholtz Centre for Heavy Ion Research15, National and Kapodistrian University of Athens16, Jan Kochanowski University17, University of Houston18, University of Paris19, University of Warsaw20, Massachusetts Institute of Technology21, Wayne State University22, Pusan National University23
TL;DR: In this paper, both the standard method of correlating particles with an event plane and the cumulant method of studying multiparticle correlations were used to reconstruct the collective motion in A+A collisions at SPS energies.
Abstract: Directed and elliptic flow measurements for charged pions and protons are reported as a function of transverse momentum, rapidity, and centrality for 40A and 158A GeV Pb+Pb collisions, as recorded by the NA49 detector. Both the standard method of correlating particles with an event plane and the cumulant method of studying multiparticle correlations are used. In the standard method the directed flow is corrected for conservation of momentum. In the cumulant method elliptic flow is reconstructed from genuine four-, six-, and eight-particle correlations, showing the first unequivocal evidence for collective motion in A+A collisions at SPS energies.
262 citations
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TL;DR: In this paper, 2 mm thick PLA sheets were injection moulded and re-crystallized in a conventional oven at 60-140°C, for 10-60 minutes to achieve various crystalline contents.
Abstract: This paper focuses on the crystalline structure of injection moulding grade poly(lactic acid) (PLA) and the effect of crystalline structure on the processing. The research is induced by the significant differences in crystallinity of the pure PLA resin, and the injection moulded product, and thus the reprocessing of PLA products. 2 mm thick PLA sheets were injection moulded and re-crystallized in a conventional oven at 60-140°C, for 10-60 minutes to achieve various crystalline contents. The properties of these sheets were investigated by dynamic mechanical analysis (DMA), differential scanning calorimetry (DSC), and wide angle X-ray diffraction (WAXD). In a processing plant the rejected parts are recycled and reused as raw material for further cycles, accordingly the various crystalline content PLA products were reprocessed as a resin, to investigate the processing itself. When PLA products are reprocessed, due to the adherent feature of amorphous PLA processing difficulties may occur. This adherent effect of the amorphous PLA was investigated and characterized.
262 citations
Authors
Showing all 21526 results
Name | H-index | Papers | Citations |
---|---|---|---|
Jasvinder A. Singh | 176 | 2382 | 223370 |
Alexander S. Szalay | 166 | 936 | 145745 |
Ashok Kumar | 151 | 5654 | 164086 |
György Buzsáki | 150 | 446 | 96433 |
Daniel Bloch | 145 | 1819 | 119556 |
Brajesh C Choudhary | 143 | 1618 | 108058 |
Geoffrey Burnstock | 141 | 1488 | 99525 |
Suman Bala Beri | 137 | 1608 | 104798 |
Vipin Bhatnagar | 137 | 1756 | 104163 |
Paul Slovic | 136 | 506 | 126658 |
Manjit Kaur | 135 | 1540 | 97378 |
Gabor Istvan Veres | 135 | 1349 | 96104 |
Dimitri Bourilkov | 134 | 1489 | 96884 |
Georges Azuelos | 134 | 1294 | 90690 |
Michael Tytgat | 134 | 1449 | 94133 |