Institution
Leicester General Hospital
Healthcare•Leicester, United Kingdom•
About: Leicester General Hospital is a healthcare organization based out in Leicester, United Kingdom. It is known for research contribution in the topics: Population & Transplantation. The organization has 2481 authors who have published 3034 publications receiving 107437 citations.
Topics: Population, Transplantation, Diabetes mellitus, Kidney, Kidney disease
Papers published on a yearly basis
Papers
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TL;DR: Despite being associated with poor initial graft function, the long-term allograft survival of NHBD kidneys does not differ significantly from the results of HBD and LD transplants.
214 citations
TL;DR: The incidence of clinically significant complications after protocol biopsy of a stable renal transplant is low, and it is ethically justifiable to ask renal transplant recipients to undergo protocol biopsies in clinical trials and routine care.
Abstract: The incidence of clinically significant complications after protocol biopsy of a stable renal transplant is low. Direct benefits to the patients concerned (irrespective of the benefit that may accrue in clinical trials) were not formally assessed but seem likely to outweigh the risk of the procedure. We believe that it is ethically justifiable to ask renal transplant recipients to undergo protocol biopsies in clinical trials and routine care.
212 citations
TL;DR: It is estimated that the potential gain of the GDS(15) in primary care to be 8% over unassisted clinical detection but at a cost of 3-4 minutes of extra time per appointment, while the G DS(30) is recommended but not in the diagnosis of late-life depression inPrimary care.
212 citations
TL;DR: There was a wide variation in the actual and estimated rates of dural tears among the spine surgeons and the results confirm that prospective data collection by spine surgeons is the most efficient and accurate way to assess complication rates for spinal surgery.
Abstract: There is increasing awareness of the need to inform patients of common complications that occur during surgical procedures. During lumbar spine surgery, incidental tear of the dural sac and subsequent cerebrospinal fluid leak is possibly the most frequently occurring complication. There is no consensus in the literature about the rate of dural tears in spine surgery. We have undertaken this study to evaluate the incidence of dural tears among spine surgeons in the United Kingdom for commonly performed spinal procedures. Prospective data was gathered for 1,549 cases across 14 institutions in the United Kingdom. The results give us a baseline rate for the incidence of dural tears. The rate was 3.5% for primary discectomy, 8.5% for spinal stenosis surgery and 13.2% for revision discectomy. There was a wide variation in the actual and estimated rates of dural tears among the spine surgeons. The results confirm that prospective data collection by spine surgeons is the most efficient and accurate way to assess complication rates for spinal surgery.
212 citations
TL;DR: A number of molecular biomarkers with prognostic significance have been identified in hepatocellular carcinoma and not only might these molecules allow more accurate prediction of prognosis for patients with HCC, but they may also provide targets for potential therapeutic agents.
210 citations
Authors
Showing all 2487 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Janet Treasure | 114 | 831 | 44104 |
| John P. Neoptolemos | 112 | 648 | 52928 |
| Paul Moayyedi | 104 | 531 | 36144 |
| Alex J. Sutton | 95 | 307 | 47411 |
| Traolach S. Brugha | 95 | 215 | 81818 |
| Kamlesh Khunti | 91 | 1030 | 37429 |
| Melanie J. Davies | 89 | 814 | 36939 |
| Kenneth J. O'Byrne | 87 | 629 | 39193 |
| Martin Roland | 86 | 410 | 31220 |
| Keith R. Abrams | 86 | 355 | 30980 |
| Charles D. Pusey | 83 | 422 | 30154 |
| Hans W. Hoek | 82 | 263 | 81606 |
| Richard Poulsom | 80 | 242 | 20567 |
| Alex J. Mitchell | 79 | 251 | 24227 |
| David C. Wheeler | 77 | 328 | 25238 |