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Institution

Leicester General Hospital

HealthcareLeicester, United Kingdom
About: Leicester General Hospital is a healthcare organization based out in Leicester, United Kingdom. It is known for research contribution in the topics: Population & Transplantation. The organization has 2481 authors who have published 3034 publications receiving 107437 citations.


Papers
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Journal ArticleDOI
TL;DR: The CCKNOW score provides a valuable index of overall knowledge and is self-administered and psychometric tests show it to be valid, reliable, and readable.

148 citations

Journal ArticleDOI
TL;DR: An international, multidisciplinary, systematic search and evidence-based review of Barrett’s esophagus and provided consensus recommendations for clinical use in patients with nondysplastic, indefinite, and low-grade dysplasia (LGD).

146 citations

Journal ArticleDOI
TL;DR: The cross-sectional correlation between pathology and proteinuria was similar in adults and children and the predictive value of each specific lesion on the rate of decline of renal function or renal survival in IgA nephropathy was not different between children and adults.

146 citations

Journal ArticleDOI
TL;DR: Pay-for-performance incentives have not addressed disparities in the management and control of diabetes between ethnic groups and quality improvement initiatives must place greater emphasis on minority communities to avoid continued disparities in mortality from cardiovascular disease and the other major complications of diabetes.
Abstract: The Wandsworth Primary Care Research Centre and the Wandsworth Prospective Diabetes Study are funded by the Department of Health. The Wandsworth Prospective Diabetes Study has also received support from the Medical Research Council through the Virtual Organisation of Trials and Epidemiological Studies (VOTES) project.

146 citations

Journal ArticleDOI
TL;DR: A better understanding of this process and the effect of disease may allow better selection of patients for partial hepatectomy and allow an insight into the possible application of clinical stimulation of regeneration.
Abstract: Background: Partial hepatectomy is the strongest stimulator of hepatic regeneration. The process of initiation and the control of the final size of the regenerated liver have been the subject of research for many years. A better understanding of this process and the effect of disease may allow better selection of patients for partial hepatectomy. It may also allow an insight into the possible application of clinical stimulation of regeneration. Methods: Data were reviewed from the published literature using the Medline database. Results: Most knowledge comes from in vitro studies and the study of resection in the rat model. A variety of cytokines, hormones and growth factors are involved in regeneration but very few have been found capable of stimulating regeneration in vitro. The exact interactions are not known, but there is probably a cascade involving different factors at differing stages of regeneration. Conclusion: Further in vivo research should allow greater understanding of liver regeneration, thereby providing a potential therapeutic tool in patients for whom regeneration has failed, or is likely to fail. Such research is also important in respect of liver support devices, which may inhibit liver regeneration by filtration of many of the factors involved. © 2002 British Journal of Surgery Society Ltd

145 citations


Authors

Showing all 2487 results

NameH-indexPapersCitations
Janet Treasure11483144104
John P. Neoptolemos11264852928
Paul Moayyedi10453136144
Alex J. Sutton9530747411
Traolach S. Brugha9521581818
Kamlesh Khunti91103037429
Melanie J. Davies8981436939
Kenneth J. O'Byrne8762939193
Martin Roland8641031220
Keith R. Abrams8635530980
Charles D. Pusey8342230154
Hans W. Hoek8226381606
Richard Poulsom8024220567
Alex J. Mitchell7925124227
David C. Wheeler7732825238
Network Information
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20233
20229
2021138
2020135
201984
201890