Showing papers by "Long Island University published in 2009"

Differences in tongue strength across age and gender: is there a diminished strength reserve?

Abstract: Maximum tongue strength was investigated and compared to mean swallowing pressure elicited by the anterior tongue to calculate the percentage of maximum tongue strength used during swallowing in 96 participants with normal swallowing, divided into three 20-year age groups. The purposes of this investigation were to investigate normal swallowing physiology and to determine whether tongue strength reserves diminished according to age or gender. The results of the study yielded significant maximum tongue strength differences between the youngest and oldest and middle and oldest age groups; the oldest group had the weakest tongues. Mean swallowing pressure did not differ based on age, but women were found to have significantly higher pressures than men. The percentage of maximum tongue strength used during swallowing did not vary as a function of age, but women used a significantly higher percentage of tongue strength to swallow than men. Based on the results, it appears that a diminishing strength reserve does not exist based on age, but it does exist based on gender. Specifically, it appears that women have a reduced tongue strength reserve compared to men. Clinical implications are discussed.

The relationship of early alliance ruptures and their resolution to process and outcome in three time-limited psychotherapies for personality disorders

Abstract: This study examined the relationship of early alliance ruptures and their resolution to process and outcome in a sample of 128 patients randomly assigned to 1 of 3 time-limited psychotherapies for personality disorders: cognitive-behavioral therapy, brief relational therapy, or short-term dynamic psychotherapy. Rupture intensity and resolution were assessed by patient- and therapist-report after each of the first 6 sessions. Results indicated that lower rupture intensity and higher rupture resolution were associated with better ratings of the alliance and session quality. Lower rupture intensity also predicted good outcome on measures of interpersonal functioning, while higher rupture resolution predicted better retention. Patients reported fewer ruptures than did therapists. In addition, fewer ruptures were reported in cognitive-behavioral therapy than in the other treatments. (PsycINFO Database Record (c) 2010 APA, all rights reserved).

Exocytosis precedes and predicts the increase in growth in oscillating pollen tubes

Abstract: We examined exocytosis during oscillatory growth in lily (Lilium formosanum and Lilium longiflorum) and tobacco (Nicotiana tabacum) pollen tubes using three markers: (1) changes in cell wall thickness by Nomarski differential interference contrast (DIC), (2) changes in apical cell wall fluorescence in cells stained with propidium iodide (PI), and (3) changes in apical wall fluorescence in cells expressing tobacco pectin methyl esterase fused to green fluorescent protein (PME-GFP). Using PI fluorescence, we quantified oscillatory changes in the amount of wall material from both lily and tobacco pollen tubes. Measurement of wall thickness by DIC was only possible with lily due to limitations of microscope resolution. PME-GFP, a direct marker for exocytosis, only provides information in tobacco because its expression in lily causes growth inhibition and cell death. We show that exocytosis in pollen tubes oscillates and leads the increase in growth rate; the mean phase difference between exocytosis and growth is –98° ± 3° in lily and –124° ± 4° in tobacco. Statistical analyses reveal that the anticipatory increase in wall material predicts, to a high degree, the rate and extent of the subsequent growth surge. Exocytosis emerges as a prime candidate for the initiation and regulation of oscillatory pollen tube growth.

Alterations in Two-Component Regulatory Systems of phoPQ and pmrAB Are Associated with Polymyxin B Resistance in Clinical Isolates of Pseudomonas aeruginosa

Abstract: Polymyxins are often the only option to treat acquired multidrug-resistant Pseudomonas aeruginosa. Polymyxin susceptibility in P. aeruginosa PAO1 is associated with the lipopolysaccharide structure that is determined by arnBCADTEF and modulated by phoPQ and pmrAB. We examined five clonally unrelated clinical isolates of polymyxin B-resistant P. aeruginosa to investigate the molecular basis of polymyxin resistance. All isolates grew with 4 microg/ml polymyxin B (MIC, 8 microg/ml), whereas P. aeruginosa PAO1 grew with 0.25 mug/ml polymyxin B (MIC, 0.5 microg/ml). The resistant isolates were converted to susceptible ones (the MICs fell from 8 to 0.5 microg/ml) following the introduction of phoPQ (four isolates) and pmrAB (one isolate), which had been cloned from strain PAO1. DNA sequence analysis revealed that a single-nucleotide substitution in three isolates replaced a single amino acid of PhoQ, the deletion of 17 nucleotides in one isolate truncated the protein of PhoQ, and two nucleotide substitutions in one isolate replaced two amino acids of PmrB. The involvement of these amino acid substitutions or the truncated protein of PhoQ and PmrB in polymyxin B resistance was confirmed using strain PAO1 lacking phoPQ or pmrAB that was transformed by phoPQ or pmrAB containing the amino acid substitutions or the truncated protein. The resistant clinical isolates were sensitized by the inactivation of arnBCADTEF (the MICs fell from 8 to 0.5 microg/ml). These results suggest that polymyxin B resistance among clinical isolates of P. aeruginosa is associated with alterations in two-component regulatory systems of phoPQ or pmrAB.

The effect of piano lessons on the vocabulary and verbal sequencing skills of primary grade students

Abstract: A number of studies have reported positive associations between music experience and increased abilities in non-musical (e.g., linguistic, mathematical, and spatial) domains in children. These transfer effects continue to be probed using a variety of experimental designs. The major aim of this quasi-experimental study was to examine the effects of a scaffolded music instruction program on the vocabulary and verbal sequencing skills of two cohorts of second-grade students. One group (n = 46) studied piano formally for a period of three consecutive years as part of a comprehensive instructional intervention program. The second group (n = 57) had no exposure to music lessons, either in school programs or private study. Both groups were assessed on two subtests from the Structure of Intellect (SOI) measure. Results revealed that the experimental group had significantly better vocabulary and verbal sequencing scores at post-test than did the control group. Data from this study will help to clarify the role of ...

Effects of task-oriented training on mobility function in children with cerebral palsy

Abstract: BACKGROUND/PURPOSE: Improvement in mobility function has been the primary goal in the rehabilitation of children with cerebral palsy. Few studies have examined the effectiveness of task-oriented strength training for children with cerebral palsy. The purpose of this study was to examine the effects of task-oriented strength training on mobility function in children with cerebral palsy. STUDY DESIGN: A single-blind, randomized controlled trial with pre-training and post-training evaluations. MATERIALS AND METHODS: Ten children with cerebral palsy (GMFCS levels I-III) were randomly assigned to an experimental group (N = 5) or control group (N = 5). Mobility function was assessed using the Gross Motor Function Measure (GMFM) and the Timed "Up and Go" (TUG) test. Participants in the control group received conventional physical therapy focused on improving walking and balance through facilitation and normalization of movement patterns. Participants in the experiment group received task-oriented strength training focused on strengthening the lower extremities and practicing functional tasks similar to those the child performs during daily activities. RESULTS: After the 5-week training period there were significant improvements in the experimental group for dimension D (p = 0.009), and dimension E (p = 0.009) of the GMFM. The experimental group significantly reduced the time taken to complete the TUG (p = 0.017). CONCLUSION/SIGNIFICANCE: This study supports the efficacy of task-oriented strength training for improving mobility function in children with cerebral palsy. The findings demonstrate that the application of a task-oriented strength training program is linked to positive functional outcomes. The results suggest that children with cerebral palsy may benefit from a task-oriented strength training program. Further studies with a larger randomized sample and longer post-intervention follow-up are necessary to document the long-term effects of participation in task-oriented strength training programs in the cerebral palsy population.

Overground physical therapy gait training for chronic stroke patients with mobility deficits

Abstract: Background Overground gait training forms a major part of physical therapy services for chronic stroke patients in almost every setting. Overground gait training refers to physical therapists' observation and cueing of the patient's walking pattern along with related exercises, but does not include high-technology aids such as functional electrical stimulation or body weight support. Objectives To assess the effects of overground physical therapy gait training on walking ability for chronic stroke patients with mobility deficits. Search methods We searched the Cochrane Stroke Group Trials Register (last searched March 2008), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library Issue 2, 2008), MEDLINE (1966 to May 2008), EMBASE (1980 to May 2008), CINAHL (1982 to May 2008), AMED (1985 to March 2008), Science Citation Index Expanded (1981 to May 2008), ISI Proceedings (Web of Science, 1982 to May 2006), Physiotherapy Evidence Database (http://www.pedro.org.au/) (May 2008), REHABDATA (http://www.naric.com/research/rehab/) (1956 to May 2008), http://www.clinicaltrials.gov (May 2008), http://www.controlled-trials.com/ (May 2008), and http://www.strokecenter.org/ (May 2008). We also searched reference lists of relevant articles, and contacted authors and trial investigators. Selection criteria Randomised controlled trials comparing overground physical therapy gait training with a placebo intervention or no treatment for chronic stroke patients with mobility deficits. Data collection and analysis Pairs of authors independently selected trials. Three authors independently extracted data and assessed quality. We contacted study authors for additional information. Main results We included nine studies involving 499 participants. We found no evidence for a benefit on the primary variable, post-test gait function, based on three studies with 269 participants. Uni-dimensional performance variables did show significant effects post-test. Gait speed increased by 0.07 metres per second (95% confidence interval (CI) 0.05 to 0.10) based on seven studies with 396 participants, timed up-and-go (TUG) test improved by 1.81 seconds (95% CI -2.29 to -1.33), and six-minute-walk test (6MWT) increased by 26.06 metres (95% CI 7.14 to 44.97) based on four studies with 181 participants. We found no significant differences in deaths/disabilities or in adverse effects, based on published reports or personal communication from all of the included studies. Authors' conclusions We found insufficient evidence to determine if overground physical therapy gait training benefits gait function in patients with chronic stroke, though limited evidence suggests small benefits for uni-dimensional variables such as gait speed or 6MWT. These findings must be replicated by large, high quality studies using varied outcome measures.

Comparison of Landing Biomechanics Between Male and Female Professional Dancers

Abstract: BackgroundThe incidence of anterior cruciate ligament injuries among dancers is much lower than that among team sport athletes and no clear gender disparity has been reported in the dance population. Although numerous studies have observed differences in lower extremity landing biomechanics between male and female athletes, there is currently little research examining the landing biomechanics of male and female dancers. Comparing landing biomechanics within this population may help explain the lower overall anterior cruciate ligament injury rates and the lack of gender disparity.HypothesisDue to the fact that dancers receive jump-specific and balance-specific training from a very young age, we hypothesized that there would be no gender differences in drop-landing biomechanics in professional dancers.Study DesignControlled laboratory study.MethodsKinematics and ground-reaction forces were recorded as 33 professional modern and ballet dancers (12 men and 21 women) performed single-legged drop landings from ...

Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions

Abstract: Heroin remains a major drug of abuse and is preferred by addicts over morphine. Like morphine, heroin has high affinity and selectivity for μ-receptors, but its residual analgesia in exon 1 MOR-1 knockout mice that do not respond to morphine suggests a different mechanism of action. MOR-1 splice variants lacking exon 1 have been observed in mice, humans, and rats, raising the possibility that they might be responsible for the residual heroin and morphine-6β-glucuronide (M6G) analgesia in the exon 1 knockout mice. To test this possibility, we disrupted exon 11 of MOR-1, which eliminates all of the variants that do not contain exon 1. Morphine and methadone analgesia in the exon 11 knockout mouse was normal, but the analgesic actions of heroin, M6G, and fentanyl were markedly diminished in the radiant heat tail-flick and hot-plate assays. Similarly, the ability of M6G to inhibit gastrointestinal transit was greatly diminished in these exon 11 knockout mice, whereas the ability of morphine was unchanged. These findings identify receptors selectively involved with heroin and M6G actions and confirm the relevance of the exon 11-associated variants and raise important issues regarding the importance of atypical truncated G-protein-coupled receptors.

Wellbeing of adult children and ageing parents: Associations with intergenerational support and relationship quality

Abstract: The current study describes from an attachment-theoretical viewpoint how ntergenerational support in adult child-parent relationships is associated with wellbeing in both generations. The attachment perspective and its focus on affective relationship characteristics is considered as an important theoretical framework for the investigation of special relationships across the life span. Data from the Netherlands Kinship Panel Study (N=1,456 dyads) were analysed to investigate if relationship quality moderated the association between providing intergenerational support to parents and wellbeing in adult children, on the one hand, and receiving intergenerational support from children and wellbeing of older parents on the other hand. The perspectives of both relationship partners were taken into account to allow for dependence within dyads. Intergenerational support, in terms of instrumental help provision, was negatively associated with the child’s and parent’s wellbeing. Being the stronger and wiser partner in adultchild parent relationships, as reflected by giving advice and being the initiator within the relationship, was beneficial for the wellbeing of both generations. Additionally, relationship quality was the strongest predictor of wellbeing in both generations. Parental wellbeing was benefited by filial support in high quality relationships. If an intergenerational relationships was of high quality, the challenges of intergenerational support provision and receipt were easier to deal with for both generations, parents and children. Key words: adult child-parent relationships, intergenerational support and wellbeing, relationship quality.

Trans-Situated Learning: Supporting a Network of Practice with an Information Infrastructure

Abstract: This paper investigates the practice-based learning dynamics that emerge among peers who share occupational practices but do not necessarily work with each other or even know each other because of geographical or organizational distance. To do so, it draws on the literatures on situated learning, networks of practice, and information infrastructures, and on insights from a longitudinal case study of the implementation of a Web-based information system used by people working in the field of environmental health. The system was deeply involved in the transformations of local practices as well as relationships between peers. Based on a dialogue between existing literatures and observations from the case study, this research extends the practice-based perspective on learning to the computer-mediated context of a network of practice. To that effect, it proposes a model of what we call trans-situated learning that is supported by the local universality of an information infrastructure whose use becomes embedded with other infrastructures.

An examination of organizational commitment and professional commitment and the relationship to work environment, demographic and organizational factors

Abstract: • Summary: This study examines organizational commitment and professional commitment among a sample of social workers. It empirically explores the relationship between social workers’ commitment and nine work environment variables (collegiality, promotional opportunity, job security, organization and profession-specific skills, autonomy, legitimacy of promotions, distributive justice and supervisor recognition), six demographic or background variables (gender, relationship status, age, employment status, years in social work (profession tenure) and years employed in the current organization (job tenure). It also includes 16 organizational variables (organizational auspices, organizational type, job position, yearly earnings and various types of job benefits, that is, medical, dental, vacation time, sick leave, flex-time, child care, maternity/paternity leave, disability insurance, life insurance, university education/degree programs, employer-paid professional development opportunities and other benefits....

Binary black holes' effects on electromagnetic fields.

Abstract: In addition to producing gravitational waves, the dynamics of a binary black hole system could induce emission of electromagnetic radiation by affecting the behavior of plasmas and electromagnetic fields in their vicinity. We here study how the electromagnetic fields are affected by a pair of orbiting black holes through the merger. In particular, we show how the binary's dynamics induce a variability in possible electromagnetically induced emissions as well as a possible enhancement of electromagnetic fields during the late-merge and merger epochs. These time dependent features will likely leave their imprint in processes generating detectable emissions and can be exploited in the detection of electromagnetic counterparts of gravitational waves.

Authoritative Classroom Management: How Control and Nurturance Work Together

Abstract: Despite broad recognition that teaching excellence requires meeting students' intellectual and social needs, teachers struggle to manage—and learning theory struggles to explain—the interplay between the academic and social dimensions of classroom life. Drawing from research on parenting and child development, the author offers parenting style theory as an explanatory framework. The author begins by describing the two primary dimensions of parenting style (control and nurturance) and the influence of various styles on children's learning and development. The author then discusses the two primary channels whereby style functions, using case studies of three classrooms to illustrate how control and nurturance interact to influence student engagement and learning. Finally, the author argues that because this theory is intuitive, robust, and comprehensive, it is an important vehicle for advancing understanding of teacher influence on student outcomes and school improvement efforts.

Impact of Commercialization of the Internet on International Trade: A Panel Study Using the Extended Gravity Model

Abstract: This article tests the proposition that information and communication technology (ICT) and the Internet have enhanced international trade. Until recently, a sufficiently lengthy series of data as not available to make valid comparisons of international trade before and after the commercialization of the Internet. The use of balanced panel data for 64 countries (representing many phases of economic development) for the years 1985 to 2005 and the instrumental variable approach of Hausman and Taylor and other panel data methods provide an adequate basis for our conclusions. The results of the study are unequivocal and robust. There is a positive and significant effect of ICT infrastructure and the availability of the Internet for commercial transactions on the volume of international trade.

A cross-continental test of the Enemy Release Hypothesis: leaf herbivory on Acer platanoides (L.) is three times lower in North America than in its native Europe

Abstract: Acer platanoides (Norway maple) is a widespread native tree species in Europe. It has been introduced to North America where it has often established dense stands in both secondary woodlands and relatively undisturbed mature woodlands. In Europe A. platanoides is also extending its original range, but generally seems to exist at much lower densities. One explanation for the ‘aggressiveness’ of invasive plants such as A. platanoides is that they have left behind pests and diseases which limit their population densities in their native lands (the enemy release hypothesis or ERH). To assess the ERH for Norway maple, a large network of collaborators assessed leaf herbivory rates in populations throughout Europe and North America. We found significantly lower total leaf herbivory (1.6% ± 0.19, n = 21 vs. 7.4% ± 1.94, n = 34) and lower fungal damage (1.0% ± 0.35, n = 13 vs. 3.7% ± 0.85, n = 34) in North America than in Europe over a 2 year period, which is consistent with the predictions of the Enemy Release Hypothesis. Across years, the average total leaf herbivory was significantly correlated with average annual temperature of the site (P 0.05). Furthermore, only populations in Europe showed very high levels of herbivory (e.g., nine sites had total leaf herbivory ranging from 10.0 to 51.2% in at least 1 year) or leaf fungal damage (only one site in North America showed high levels of fungal damage in 1 year), suggesting the possibility of more frequent episodic outbreaks in the native range. Leaf herbivory and fungal damage are only two aspects of consumer pressure and we do not know whether the differences reported here are enough to actually elicit release from top-down population control, but such large scale biogeographic differences in herbivory contribute towards understanding exotic invasions.

Long Term Performance of Leveraged ETFs

Abstract: In this paper, we study leveraged ETFs, in particular, Ultra ETFs and UltraShort ETFs from the ProShares family. These Ultra (UltraShort) ETFs are designed to provide twice (twice the opposite) of the performance of the benchmark on a daily basis. We focus on the relation between long term performance of leveraged ETFs and benchmarks. Our results show that over holding periods no greater than one month, an investor can safely assume that the Ultra (UltraShort) ETF would provide twice the return (twice the negative return) of the underlying benchmark. Over the holding period of one quarter, the UltraShort ETFs can deviate from twice the negative returns of the benchmark. For Ultra ETFs, this deviation occurs when the holding period is one year. Finally, we show that the long term performance of the leveraged ETFs is negatively impacted by the quadratic variation and the auto-variation during the period, with auto-variation being the more dominant factor.

The association of family support and wellbeing in later life depends on adult attachment style

Abstract: The current study examines the association between family support and wellbeing in the elderly, paying particular attention to the possible moderating role of attachment style. Data from a community-dwelling, ethnically diverse, elderly sample (N = 1118) were analyzed to determine the best linear combination of emotional support, instrumental support, and attachment styles predicting wellbeing. Emotional support generally was associated with higher wellbeing whereas instrumental support was related to decreased wellbeing. As expected, however, these associations were qualified by attachment style. Receiving emotional support had stronger positive and instrumental support less negative effects on the wellbeing of elderly individuals with higher attachment security. Given increased longevity, family networks may become important sources of support for the elderly. Work detailing when, how, and for whom particular types of family support are beneficial is a key agenda within developmental psychology and social gerontology.

Perturbed disks get shocked. Binary black hole merger effects on accretion disks

Abstract: The merger process of a binary black hole system can have a strong impact on a circumbinary disk. In the present work we study the effect of both central mass reduction (due to the energy loss through gravitational waves) and a possible black hole recoil (due to asymmetric emission of gravitational radiation). For the mass reduction case and recoil directed along the disk's angular momentum, oscillations are induced in the disk which then modulate the internal energy and bremsstrahlung luminosities. On the other hand, when the recoil direction has a component orthogonal to the disk's angular momentum, the disk's dynamics are strongly impacted, giving rise to relativistic shocks. The shock heating leaves its signature in our proxies for radiation, the total internal energy and bremsstrahlung luminosity. Interestingly, for cases where the kick velocity is below the smallest orbital velocity in the disk (a likely scenario in real active galactic nuclei), we observe a common, characteristic pattern in the internal energy of the disk. Variations in kick velocity simply provide a phase offset in the characteristic pattern implying that observations of such a signature could yield a measure of the kick velocity through electromagnetic signals alone.

The Posttraumatic Growth Model: An Expansion to the Family System

Abstract: This article focuses on expanding Calhoun and Tedeschi's model of posttraumatic growth (PTG) to the family system level. PTG has been conceptualized as an outcome on multiple levels, including individuals, families, and communities. However, in the original model the family is mostly viewed as the context for individual growth, whereas in this article the family is the unit that grows. The proposed conceptualization is consistent with the paradigmatic shift from a deficit-based perspective to a strength-based perspective of family functioning in general and in the aftermath of trauma in particular. The first part of the article briefly introduces the PTG model. The second part identifies and illustrates the family system parallels of the six components of the model: pretrauma characteristics, a traumatic/ highly stressful event, challenges, rumination, social context, and posttraumatic growth. The third part addresses future directions.

Validating Work Discrimination and Coping Strategy Models for Sexual Minorities.

Abstract: The purpose of this study was to validate and expand on Y. B. Chung's (2001) models of work discrimination and coping strategies among lesbian, gay, and bisexual persons. In semistructured individual interviews, 17 lesbians and gay men reported 35 discrimination incidents and their related coping strategies. Responses were coded based on Chung's models. Results supported the validity of the Work Discrimination model and two coping strategy models (Vocational Choice and Identity Management). The Discrimination Management coping strategy model was expanded. Implications for practice and research are discussed. In a special issue of The Career Development Quarterly (Savickas, 2003) that was devoted to trend analyses of career development literature and projections for the next decade, Chung (2003a) identified one significant and cutting-edge development of this literature - the vocational behavior of lesbian, gay, and bisexual (LGB) persons. He stated that conceptual and practical articles about the career development of LGB persons began to emerge in the late 1980s and early 1990s (e.g., Elliott, 1993; Hetherington, Hillerbrand, & Etringer, 1989; Hetherington & Orzek, 1989), followed by theoretical and empirical work during the past decade (e.g., Bieschke & Matthews, 1996; Chung, 2001; Rostosky & Riggle, 2002). Two of the most important areas of inquiry regarding the vocational behavior of LGB persons are work discrimination and coping strategies (Chung, 2001 , 2003b; Croteau, Anderson, DiStefano, & Kampa-Kokesch, 2000). Discrimination in the workplace is an existing barrier that affects LGB persons, and researchers have suggested that work discrimination has a profound effect on the well-being of this population (Croteau, 1996; Croteau Sc Hedstrom, 1993; Driscoll, Kelley, & Fassinger, 1996; Elliott, 1993; Fassinger, 1995, 1996; Griffin, 1992; Hetherington et al., 1989; Levine & Leonard, 1984; Morgan 8c Brown, 1991; Orzek, 1992; Pope, 1995, 1996; Worthington, McCrary, Sc Howard, 1998). In response to discrimination, LGB persons must learn to develop effective coping strategies (Griffin, 1992; Levine & Leonard, 1984; Pope, 1996). It is essential for career counselors to understand the various forms of work discrimination, their effects, and various coping strategies that correspond to the individual needs and self-efficacy of LGB clients. Chung (2001) proposed two conceptual frameworks about work discrimination and coping strategies based on an integration of existing literarure. He defined work discrimination as "unfair and negative treatment of workers or job applicants based on personal attributes that are irrelevant to job performance" (Chung, 2001 , p. 34). His Work Discrimination model describes the nature of work discrimination along three dimensions: (a) formal versus informal, (b) perceived versus real, and (c) potential versus encountered. Formal discrimination pertains to institutional policies or decisions that affect an employee's status of employment (e.g., being hired or fired, receiving a promotion), job assignment, and compensation. Informal discrimination refers to workplace behavior or atmosphere that is hostile or not welcoming. Perceived discrimination involves acts that are discriminatory according to perceptions; whereas real discrimination is based on actuality. Potential cuscrirnination refers to possible discrimination that would occur should a person's LGB identity become known or be assumed. Encountered discrimination is discriminatory acts that the person experiences. These three dimensions (2x2x2) describe eight types of work discrimination (e.g., perceived-potential-formai discrimination, real-encountered-informal discrimination). How these eight types of work discrimination are manifested under various federal and state laws or institutional discrimination policies and how they affect employees' well-being and coping are worthy topics for investigation. …

Overground Gait Training for Individuals with Chronic Stroke: A Cochrane Systematic Review

Abstract: Background and Purpose:Overground gait training—observation and cueing of patient’s walking pattern along with related exercises—forms a major part of rehabilitation services for individuals with chronic stroke in almost every setting. This report of a Cochrane systematic review assessed the effects

Rivaroxaban: a novel, oral, direct factor Xa inhibitor.

Abstract: Thromboembolic disorders such as deep vein thrombosis, pulmonary embolism, myocardial infarction, and stroke often result in long-term disability and/or mortality. The anticoagulants currently available have been effective in the treatment and prevention of these disorders; however, parenteral administration, variable pharmacokinetics and pharmacodynamics, drug and dietary interactions, and a requirement for frequent monitoring of efficacy and safety limit use of these drugs. Rivaroxaban is a novel, oral factor Xa inhibitor in clinical development for the treatment and prevention of thromboembolic diseases. Rivaroxaban is a small molecule directed at active sites, and the agent mechanistically differs from traditional anticoagulants, such as heparins and fondaparinux, in that its activity is independent of antithrombin and its ability to inhibit prothrombinase bound factor Xa. In addition, preclinical and clinical trial data indicate that rivaroxaban has predictable pharmacokinetics and pharmacodynamics, which are features that differentiate it from oral vitamin K antagonists. Phase II studies showed that rivaroxaban is safe and well tolerated across a wide range of doses. Furthermore, completed phase III studies demonstrated its efficacy in the prevention of venous thromboembolism after orthopedic surgery. Additional studies are now under way to evaluate the use of rivaroxaban in the treatment and prevention of other venous and arterial thromboembolic conditions.

Clinical and conceptual problems in the attribution of malingering in forensic evaluations.

Abstract: The authors review clinical and conceptual errors that contribute to false attributions of malingering in forensic evaluations. Unlike the mental disorders, malingering is not defined by a set of (relatively) enduring symptoms or traits; rather, it is an intentional, externally motivated, and context-specific form of behavior. Despite this general knowledge, attributions of malingering are often made by using assessment tools that may detect feigning but cannot be relied upon to determine incentive and volition or consciousness (defining characteristics of malingering). In addition, forensic evaluators may overlook the possibility that feigning is a function of true pathology, as in Ganser syndrome or the factitious disorders, or that a seemingly malingered presentation is due to symptoms of an underlying disorder, such as dissociative identity disorder (DID). Other factors that set the stage for false positives, such as pressure on forensic specialists to identify malingering at all costs, failure to consider the base rate problem, and cultural variables, are also reviewed.