Institution
Montreal Children's Hospital
Healthcare•Montreal, Quebec, Canada•
About: Montreal Children's Hospital is a healthcare organization based out in Montreal, Quebec, Canada. It is known for research contribution in the topics: Population & Poison control. The organization has 3842 authors who have published 4816 publications receiving 200198 citations.
Topics: Population, Poison control, Gene, Medicine, Kidney
Papers published on a yearly basis
Papers
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TL;DR: The results imply that the premature infant has the basis for communicating pain via facial actions but that these are not well developed, while the full‐term newborn is better equipped to interact with his caretakers and express his distress through specific facial actions.
Abstract: The purpose of this study was to examine the behavioural responses of infants to pain stimuli across different developmental ages. Eighty infants were included in this cross-sectional design. Four subsamples of 20 infants each included: 1. (1) premature infants between 32 and 34 weeks gestational age undergoing heel-stick procedure; 2. (2) full-term infants receiving intramuscular vitamin K injection; 3. (3) 2-month-old infants receiving subcutaneous injection for immunisation against DPT; 4. (4) 4-month-old infants receiving subcutaneous injection for immunisation against DPT. Audio and video recordings were made for 15 sec from stimulus. Cry analysis was conducted on the first full expiratory cry by FFT with time and frequency measures. Facial action was coded using the Neonatal Facial Action Coding System (NFCS). Results from multivariate analysis showed that premature infants were different from older infants, that full-term newborns were different from others, but that 2- and 4-month-olds were similar. The specific variables contributing to the significance were higher pitched cries and more horizontal mouth stretch in the premature group and more taut tongue in the full-term newborns. The results imply that the premature infant has the basis for communicating pain via facial actions but that these are not well developed. The full-term newborn is better equipped to interact with his caretakers and express his distress through specific facial actions. The cries of the premature infant, however, have more of the characteristics that are arousing to the listener which serve to alert the caregiver of the state of distress from pain.
259 citations
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University of Calgary1, McGill University Health Centre2, Libin Cardiovascular Institute of Alberta3, University of British Columbia4, Montreal Children's Hospital5, Université du Québec à Trois-Rivières6, Université de Montréal7, Laval University8, McMaster University9, University of Alberta10, University of Toronto11, Ottawa Hospital Research Institute12, Hôpital Maisonneuve-Rosemont13, University of Western Ontario14, Memorial University of Newfoundland15, Centre for Addiction and Mental Health16, University of Ottawa17, McGill University18, University Health Network19, University of Saskatchewan20, University of Manitoba21, Concordia University Wisconsin22, St. Michael's Hospital23, Montreal General Hospital24, Heart and Stroke Foundation of Canada25, Dalhousie University26, Université de Sherbrooke27, Université du Québec à Montréal28, Montreal Heart Institute29, Population Health Research Institute30, Simon Fraser University31, St George's, University of London32, Centre Hospitalier Universitaire Sainte-Justine33, Children's Hospital of Eastern Ontario34
TL;DR: Hypertension Canada provides annually updated, evidence-based guidelines for the diagnosis, assessment, prevention, and treatment of hypertension, including 10 new guidelines for individuals with non-AOBP readings ≥ 140 mm Hg.
256 citations
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TL;DR: Significant pre- to post-treatment gains were found on measures of both social competence and problem behaviors associated with AS/HFA, and parent-reported improvement suggests that social skills learned in group sessions generalize to settings outside the treatment group.
Abstract: The effectiveness of a social skills training group for adolescents with Asperger syndrome and high-functioning autism (AS/HFA) was evaluated Parents of six groups of adolescents (n = 46, 61% male, mean age 146) completed questionnaires immediately before and after the 12-week group Parents and adolescents were surveyed regarding their experience with the group Significant pre- to post-treatment gains were found on measures of both social competence and problem behaviors associated with AS/HFA Effect sizes ranged from 34 to 72 Adolescents reported more perceived skill improvements than did parents Parent-reported improvement suggests that social skills learned in group sessions generalize to settings outside the treatment group Larger, controlled studies of social skills training groups would be valuable
255 citations
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TL;DR: Results of this study suggest that the greater number of abnormally long RTs of children with ADHD reflect attentional lapses on some but not all trials and demonstrate why slower RT is found when estimates of variability assume normal Gaussian distributions.
Abstract: Differences in reaction time (RT) variability have been documented between children with and without Attention Deficit Hyperactivity Disorder (ADHD). Most previous research has utilized estimates of normal distributions to examine variability. Using a nontraditional approach, the present study evaluated RT distributions on the Conners’ Continuous Performance Test in children and adolescents from the Multimodal Treatment Study of ADHD sample compared to a matched sample of normal controls (n = 65 pairs). The ex-Gaussian curve was used to model RT and RT variability. Children with ADHD demonstrated faster RT associated with the normal portion of the curve and a greater proportion of abnormally slow responses associated with the exponential portion of the curve. These results contradict previous interpretation that children with ADHD have slower than normal responding and demonstrate why slower RT is found when estimates of variability assume normal Gaussian distributions. Further, results of this study sugg...
255 citations
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TL;DR: Gene therapy for RPE65 deficient dogs partially restored sight, and provides the first real hope of treatment for this devastating blinding condition.
254 citations
Authors
Showing all 3844 results
Name | H-index | Papers | Citations |
---|---|---|---|
Paul M. Matthews | 140 | 617 | 88802 |
Joost J. Oppenheim | 130 | 454 | 59601 |
Michael Camilleri | 125 | 1084 | 58867 |
James M. Swanson | 117 | 415 | 47131 |
Rhian M. Touyz | 114 | 620 | 43738 |
Ian Roberts | 112 | 714 | 51933 |
William D. Foulkes | 108 | 682 | 45013 |
Stephen P. Hinshaw | 106 | 330 | 37336 |
Michael S. Kramer | 104 | 568 | 43803 |
Liam Smeeth | 104 | 753 | 53433 |
Eric Fombonne | 100 | 336 | 44447 |
Douglas L. Arnold | 100 | 624 | 37040 |
Erwin W. Gelfand | 99 | 675 | 36059 |
Frederick Andermann | 90 | 365 | 25638 |
Robert W. Platt | 88 | 638 | 31918 |