Institution
Pan American Health Organization
Healthcare•Havana, Cuba•
About: Pan American Health Organization is a healthcare organization based out in Havana, Cuba. It is known for research contribution in the topics: Population & Public health. The organization has 1500 authors who have published 2263 publications receiving 83705 citations. The organization is also known as: HO Regional Office for the Americas.
Topics: Population, Public health, Health care, Latin Americans, Vaccination
Papers published on a yearly basis
Papers
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Pan American Health Organization1, University of Oxford2, World Health Organization3, Churchill Hospital4, University of London5, Swiss Tropical and Public Health Institute6, University of Basel7, Cayetano Heredia University8, Centers for Disease Control and Prevention9, University of Barcelona10, International Military Sports Council11, Pasteur Institute12, Walter and Eliza Hall Institute of Medical Research13, Mahidol University14, University of Antananarivo15, Burnet Institute16, University of Melbourne17
TL;DR: This report presents and discusses the rationale for these P. vivax-specific diagnostic target product profiles, which contribute to the rational development of fit-for-purpose diagnostic tests suitable for the clinical management, control and elimination of this species.
Abstract: The global prevalence of malaria has decreased over the past fifteen years, but similar gains have not been realized against Plasmodium vivax because this species is less responsive to conventional malaria control interventions aimed principally at P. falciparum. Approximately half of all malaria cases outside of Africa are caused by P. vivax. This species places dormant forms in human liver that cause repeated clinical attacks without involving another mosquito bite. The diagnosis of acute patent P. vivax malaria relies primarily on light microscopy. Specific rapid diagnostic tests exist but typically perform relatively poorly compared to those for P. falciparum. Better diagnostic tests are needed for P. vivax. To guide their development, FIND, in collaboration with P. vivax experts, identified the specific diagnostic needs associated with this species and defined a series of three distinct target product profiles, each aimed at a particular diagnostic application: (i) point-of-care of acutely ill patients for clinical care purposes; (ii) point-of-care asymptomatic and otherwise sub-patent residents for public health purposes, e.g., mass screen and treat campaigns; and (iii) ultra-sensitive not point-of-care diagnosis for epidemiological research/surveillance purposes. This report presents and discusses the rationale for these P. vivax-specific diagnostic target product profiles. These contribute to the rational development of fit-for-purpose diagnostic tests suitable for the clinical management, control and elimination of P. vivax malaria.
25 citations
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TL;DR: The meningococcal carriage rate was lower than those reported in Europe and Africa, but higher than in other Latin American countries, and data revealed antigenic and genetic diversity of the isolates and the circulation of strains belonging to clonal complexes commonly associated with meningitis.
Abstract: Background
Meningococcal carriage studies are important to improve our understanding of the epidemiology of meningococcal disease. The aim of this study was to determine the prevalence of meningococcal carriage and the phenotypic and genotypic characteristics of isolates collected from a sample of students in the city of Bogota, Colombia.
Materials and Methods
A total of 1459 oropharyngeal samples were collected from students aged 15–21 years attending secondary schools and universities. Swabs were plated on a Thayer Martin agar and N. meningitidis was identified by standard microbiology methods and PCR.
Results
The overall carriage prevalence was 6.85%. Carriage was associated with cohabitation with smokers, and oral sex practices. Non-groupable and serogroup Y isolates were the most common capsule types found. Isolates presented a high genetic diversity, and circulation of the hypervirulent clonal complexes ST-23, ST-32 and ST-41/44 were detected.
Conclusion
The meningococcal carriage rate was lower than those reported in Europe and Africa, but higher than in other Latin American countries. Our data also revealed antigenic and genetic diversity of the isolates and the circulation of strains belonging to clonal complexes commonly associated with meningococcal disease.
25 citations
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World Health Organization1, Illinois College of Optometry2, University of Cambridge3, Anglia Ruskin University4, Moorfields Eye Hospital5, University of London6, University of Melbourne7, Sun Yat-sen University8, International Institute of Minnesota9, The Fred Hollows Foundation10, Dubai Health Authority11, Brien Holden Vision Institute12, University of New South Wales13, Pan American Health Organization14, Institute for Health Metrics and Evaluation15, Capital Medical University16
TL;DR: In this paper, the authors proposed that effective cataract surgery coverage (eCSC) and effective refractive error coverage ( eREC) serve as ideal indicators to track progress in the uptake and quality of eye care services at the global level, and to monitor progress towards universal health coverage in general.
25 citations
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TL;DR: The goal of this paper is to describe the adverse events following immunization against YF in Argentina during the outbreak in the northeastern province of Misiones, which occurred from January 2008 to January 2009.
25 citations
01 Jan 1990
TL;DR: In this article, the authors investigated the potential health effects of air pollution in Latin America and found that the population exposed to air-pollutant levels exceeding WHO guidelines can be estimated to 81 million or 26.5% of the total urban population of Latin American and 19% of its total population.
Abstract: In the last few years, air pollution has become a major issue in some countries of Latin America and the Caribbean because of urban development and growing industrialization. In addition to industrial processes often concentrated in the cities, vehicle emission and stationary-source fuel combustion are the primary sources of air pollution. Although air-quality standards have been established in some Latin American countries, these are frequently exceeded. Adverse health effects of air pollution have been mainly associated with the following pollutants: sulfur dioxide and particulate matter, photochemical oxidants, nitrogen dioxide and carbon monoxide, and lead. Short-term as well as long-term effects can be expected at levels exceeding WHO guidelines. The Latin American urban areas most affected by anthropogenic pollutant emissions are: the area of Sao Paulo (Brazil), the city of Santiago (Chile) and the metropolitan area of Mexico City. However, situations similar to those prevailing in these cities could well occur in other cities of Latin America and the Caribbean. The population exposed to air-pollutant levels exceeding WHO guidelines can be estimated to 81 million or 26.5% of the total urban population of Latin America and 19% of its total population. These estimates correspond to 30 million children (0-14), 47 million adults (15-59) and 4 million elderly people (60+). To date a very limited number of epidemiological studies have been carried out to determine the potential health effects of air pollutants in Latin America. To obtain a rough estimate, a scenario was hypothesized in which subjects living in cities would be exposed to a given level of air pollutant, using data from the international literature to extrapolate the expected number of events in different strata of the hypothetical population. The estimated health effects are considerable and warrant priority control intervention. This is true although epidemiological studies are needed to evaluate the health impact of specific pollutant compounds as well as their interactions in Latin American populations exposed to high levels of pollution.
25 citations
Authors
Showing all 1503 results
Name | H-index | Papers | Citations |
---|---|---|---|
Marcello Tonelli | 128 | 701 | 115576 |
Stephen L. Hoffman | 104 | 458 | 38597 |
Peter Singer | 94 | 702 | 37128 |
James C. Anthony | 94 | 401 | 43875 |
Bruce G. Link | 92 | 307 | 45777 |
Andrew E. Skodol | 88 | 252 | 24975 |
Marie T. Ruel | 77 | 300 | 22862 |
Franco M. Muggia | 64 | 393 | 18587 |
María G. Guzmán | 63 | 272 | 15992 |
Rob McConnell | 63 | 250 | 17973 |
José M. Belizán | 53 | 198 | 11892 |
Agustin Conde-Agudelo | 52 | 87 | 12009 |
Denise L. Doolan | 49 | 199 | 10581 |
Brendan Flannery | 48 | 177 | 8004 |
Martha Sedegah | 45 | 120 | 9304 |