Peking Union Medical College Hospital

About: Peking Union Medical College Hospital is a healthcare organization based out in Beijing, China. It is known for research contribution in the topics: Medicine & Population. The organization has 15996 authors who have published 16018 publications receiving 226505 citations.

Rapidly increasing rates of hip fracture in Beijing, China.

Abstract: The age-specific rates of hip fractures have been declining in most countries in the West but a few studies suggest that the rates might be increasing in areas of Asia that are undergoing urbanization. We previously conducted a population-based study of hip fracture rates in Beijing, China, in 1990 to 1992 that included validation of hip fracture cases. Using a similar approach to validate cases, we estimated the age-specific hip fracture rates in Beijing, China, for 2002 to 2006. Specifically, we obtained hospital discharge data for hip fractures that were reported to the Beijing Bureau of Public Health. To confirm the diagnoses, Beijing residence, and find cases missed by the public records we checked individual cases in the public health records against medical records in a random sample of Beijing hospitals. The rates from public health data were adjusted for these under- and overestimations. We found that between 1990 and 1992 and 2002 and 2006, the adjusted age-specific rates of hip fracture over age 50 years increased 2.76-fold (95% confidence interval [CI], 2.68-2.84) in women and 1.61-fold (95% CI, 1.56-1.66) in men. Over age 70 years, the age-specific rates increased 3.37-fold (95% CI, 3.28-3.47) in women and 2.01-fold (95% CI, 1.95-2.07) in men. From 2002 to 2006, the rates over age 50 years increased 58% in women and 49% in men. We conclude that the rate of hip fracture has been rising very rapidly in Beijing, China. Therefore, the burden of hip fractures may be shifting rapidly from the West to urbanizing areas of the East.

A morphological study of the foveal avascular zone in patients with diabetes mellitus using optical coherence tomography angiography.

Abstract: To investigate the area and radius of the foveal avascular zone (FAZ) in patients with diabetes mellitus (DM) using optical coherence tomography (OCT) angiography. Sixty-five patients with DM (113 eyes) and 62 healthy controls (85 eyes) were included in the study. All of the participants underwent examination with OCT angiography. The vertical radius (VR), horizontal radius (HR) and area of the FAZ were measured. The differences in HR, VR and area between the control and DM groups were statistically significant (p = 0.01, 0.00 and 0.00, respectively). There were no statistically significant differences between the control group and the no-diabetic retinopathy (DR) group in HR or VR (p = 0.07 and 0.08, respectively), but there was a statistically significant difference in area (p = 0.04). The size of the FAZ was greater in patients with DR compared to the control group. The differences in HR, VR and area were statistically significant (p = 0.01, 0.00 and 0.00, respectively). In addition, the clinically significant macular oedema (CSME) group also had a larger FAZ area than the non-CSME group (p = 0.02). Patients with DM had a larger FAZ, and patients with more severely damaged retinas had a much larger FAZ. OCT angiography is a new convenient and noninvasive method for studying the FAZ. This novel examination will yield considerable amounts of data that cannot be obtained using previous research methods.