Institution
Rowett Research Institute
About: Rowett Research Institute is a based out in . It is known for research contribution in the topics: Rumen & Population. The organization has 2986 authors who have published 4459 publications receiving 239472 citations.
Topics: Rumen, Population, Leptin, Amino acid, Adipose tissue
Papers published on a yearly basis
Papers
More filters
••
TL;DR: RT-PCR indicates that the leptin receptor, Ob-R, and in particular the Ob-Ra splice variant are expressed in a wide range of tissues, but the long form leptin receptor (Ob-Rb) was only expressed at significant levels in the medulla of the adrenal and the inner zone of the medullary of the kidney.
340 citations
••
TL;DR: It is suggested that utilization of exogenous purines may only occur in the intestinal mucosa and that the remaining purines might be completely converted, before entering the liver, to uric acid and allantoin, which are subsequently eliminated by the renal and extrarenal routes.
Abstract: Two steers totally nourished by intragastric infusion of volatile fatty acids and casein were given an abomasal infusion of a microbial protein preparation (Pruteen) at eight rates with a purine input ranging from 0 to 170 mmol/day over 11 successive 5-day periods. The urinary excretion of purine derivatives relative to the purine input was measured. Negligible amounts of xanthine plus hypoxanthine were present in the urine. The relative contributions of allantoin and uric acid to the total excretion were not affected by the rate of purine infusion. Total purine derivative excretion (uric acid and allantoin) was linearly correlated with purine input. Recovery in the urine of the infused purines was 0·77. It is suggested that utilization of exogenous purines may only occur in the intestinal mucosa and that the remaining purines may be completely converted, before entering the liver, to uric acid and allantoin, which are subsequently eliminated by the renal and extrarenal routes. The differences between cattle and sheep in excretion of purine derivatives, and the implications of these differences for the use of purine excretion values in order to estimate microbial protein supply to the ruminant, are discussed.
337 citations
••
TL;DR: The FTO genotype was significantly associated with variation in energy intake, with average daily intake being 9.0 MJ for the wild‐type TT genotype and 10.0MJ for the “at risk” AT and AA genotypes, respectively.
Abstract: The FTO gene has significant polymorphic variation associated with obesity, but its function is unknown. We screened a population of 150 whites (103F/47M) resident in NE Scotland, United Kingdom, for variants of the FTO gene and linked these to phenotypic variation in their energy expenditure (basal metabolic rate (BMR) and maximal oxygen consumption VO 2 max) and energy intake. There was no significant association between the FTO genotype and BMR or VO 2 max. The FTO genotype was significantly associated (P = 0.024) with variation in energy intake, with average daily intake being 9.0 MJ for the wild-type TT genotype and 10.2 and 9.5 MJ for the “at risk” AT and AA genotypes, respectively. Adjusting intake for BMR did not remove the significance (P = 0.043). FTO genotype probably affects obesity via effects on food intake rather than energy expenditure.
334 citations
01 Jan 1994
TL;DR: The body mass index is a measure of chronic energy deficiency in adults that measures the intensity of an individual's energy consumption over a 12-month period.
Abstract: Body mass index; A measure of chronic energy deficiency in adults , Body mass index; A measure of chronic energy deficiency in adults , کتابخانه مرکزی دانشگاه علوم پزشکی تهران
325 citations
••
325 citations
Authors
Showing all 2986 results
Name | H-index | Papers | Citations |
---|---|---|---|
Sundeep Khosla | 115 | 544 | 55451 |
Andrew Collins | 100 | 684 | 40634 |
Harry J. Flint | 99 | 293 | 43712 |
Alan Crozier | 95 | 338 | 29741 |
William M. O'Fallon | 95 | 187 | 29373 |
John R. Speakman | 95 | 667 | 34484 |
Boris Zhivotovsky | 92 | 358 | 50297 |
Michael E. J. Lean | 92 | 411 | 30939 |
Nigel W. Bunnett | 91 | 348 | 31214 |
John D. Hayes | 86 | 257 | 33146 |
Ruth McPherson | 85 | 305 | 50535 |
Bernard Portmann | 85 | 326 | 26442 |
Olle Ljungqvist | 84 | 340 | 28386 |
Michael H. Hastings | 78 | 226 | 23486 |
Ronald J. Maughan | 78 | 360 | 18100 |