Institution
Rowett Research Institute
About: Rowett Research Institute is a based out in . It is known for research contribution in the topics: Rumen & Population. The organization has 2986 authors who have published 4459 publications receiving 239472 citations.
Topics: Rumen, Population, Leptin, Amino acid, Adipose tissue
Papers published on a yearly basis
Papers
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TL;DR: Melatonin acts directly on anterior-pituitary cells, and these then relay the photoperiodic message back into the hypothalamus to control neuroendocrine output, which provides the missing link between the pineal melatonin signal and thyroid-dependent seasonal biology.
350 citations
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TL;DR: It is suggested that, in rapidly dividing ceils, high rates of glycolysis and glutaminolysis are required not for energy or precursor provision per se but for high sensitivity of the pathways involved in the use of precursors for macromolecular synthesis to specific regulators to permithigh rates of proliferation when required for example, in lymphocytes in response to a massive infection.
Abstract: The rates of utilization of both glucose and glutamine are high in rapidly dividing ceils such as enterocytes, lymphocytes, thymocytes, tumour cells; the oxidation of both glucose and glutamine is only partial, glucose to lactate and glutamine to glutamate , alanine or aspartate ; and these partial processes are termed glycolysis and glutaminolysis respectively . Both processes generate energy and also provide precursors for important biosynthetic processes in such cells. However, the rates of utilization of precursors for macromolecular biosynthesis are very low in comparison to the rates oi partial oxidation, and energy generation per se may not be the correct explanation for high rates of glycolysis and glutaminolysis in these cells since oxidation is only partial and other fuels can be used to generate energy. Both the high fluxes and the metabolic characteristics of these two processes can be explained by application of quantitative principles of control as applied to branched metabolic pathway s (Crabtree & Newsholme, 1985). If the flux through one branch is greatly in excess of the other, then the sensitivity of the flux of the low-flux pathway to regulators is very high. Hence, it is suggested that, in rapidly dividing ceils, high rates of glycolysis and gtutaminolysis are required not for energy or precursor provision per se but for high sensitivity of the pathways involved in the use of precursors for macromolecular synthesis to specific regulators to permithigh rates of proliferation when required for example, in lymphocytes in response to a massive infection.
350 citations
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TL;DR: Variations in the efficiency of the absorption and excretion of copper appear to reflect variations in the intake of other hepatotoxic or protective factors, differences in the cellular distribution of copper, and Differences in the expression of specific copper transport and storage proteins.
342 citations
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TL;DR: In this article, it was shown that the reduction of the rumen pH (to 6.0-6.1) in sheep given roughage led to the inhibition of cellulolysis and partial destruction and washout of rumen microflora.
342 citations
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TL;DR: Pure-culture studies indicated that the species most sensitive to EO were ammonia-hyperproducing bacteria and anaerobic fungi.
Abstract: A commercial blend of essential oil (EO) compounds was added to a grass, maize silage, and concentrate diet fed to dairy cattle in order to determine their influence on protein metabolism by ruminal microorganisms. EO inhibited (P < 0.05) the rate of deamination of amino acids. Pure-culture studies indicated that the species most sensitive to EO were ammonia-hyperproducing bacteria and anaerobic fungi.
341 citations
Authors
Showing all 2986 results
Name | H-index | Papers | Citations |
---|---|---|---|
Sundeep Khosla | 115 | 544 | 55451 |
Andrew Collins | 100 | 684 | 40634 |
Harry J. Flint | 99 | 293 | 43712 |
Alan Crozier | 95 | 338 | 29741 |
William M. O'Fallon | 95 | 187 | 29373 |
John R. Speakman | 95 | 667 | 34484 |
Boris Zhivotovsky | 92 | 358 | 50297 |
Michael E. J. Lean | 92 | 411 | 30939 |
Nigel W. Bunnett | 91 | 348 | 31214 |
John D. Hayes | 86 | 257 | 33146 |
Ruth McPherson | 85 | 305 | 50535 |
Bernard Portmann | 85 | 326 | 26442 |
Olle Ljungqvist | 84 | 340 | 28386 |
Michael H. Hastings | 78 | 226 | 23486 |
Ronald J. Maughan | 78 | 360 | 18100 |