scispace - formally typeset
Search or ask a question
Institution

Southern Illinois University School of Medicine

EducationSpringfield, Illinois, United States
About: Southern Illinois University School of Medicine is a education organization based out in Springfield, Illinois, United States. It is known for research contribution in the topics: Population & Cancer. The organization has 3747 authors who have published 5977 publications receiving 209115 citations. The organization is also known as: SIU School of Medicine.
Topics: Population, Cancer, Ototoxicity, Receptor, Health care


Papers
More filters
Journal ArticleDOI
TL;DR: This review provides a contemporary perspective of tremor pathophysiology while acknowledging that no form of tre tremors is understood completely and in many instances the underlying pathology is unknown.
Abstract: Physiologic and pathologic tremors are mechanistically classified into two broad groups: (1) those produced by oscillation in sensorimotor loops, so-called mechanical-reflex tremors, and (2) those produced by the oscillatory properties of central neuronal networks. This review provides a contemporary perspective of tremor pathophysiology while acknowledging that no form of tremor is understood completely. Indeed, the origin of oscillation in most forms of tremor is undefined, and in many instances the underlying pathology is unknown.

268 citations

Journal ArticleDOI
TL;DR: There appears to be a resistance of the psychiatric symptoms associated with dementia to respond to prescribed psychotropic medications.
Abstract: In a survey of drug prescribing, we interviewed 41 dementia patients and 37 normal elderly, both groups living in their homes. We found that 83 percent of the dementia patients and more than half (54 percent) of the normal elderly were receiving medications. The use of psychotropic medications was mainly limited to the dementia group, who continued to show psychopathology as measured by the BPRS (Brief Psychiatric Rating Scale) in spite of pharmacotherapy. The degree of dementia measured by Mini-Mental State examination1 was significantly correlated with the degree of psychopathology measured by Brief Psychiatric Rating Scale (BPRS).2 Polypharmacy (use of multiple psychotropic drugs) was not a problem in our sample. There appears to be a resistance of the psychiatric symptoms associated with dementia to respond to prescribed psychotropic medications.

266 citations

Journal ArticleDOI
TL;DR: Tolerance to ethanol results in enhanced EAA neurotransmission and NMDA receptor upregulation, which appears to involve selective increases in NMDAR2B subunit levels and other molecular changes in specific brain loci, but these data are complex and somewhat contradictory at present.

264 citations

Journal ArticleDOI
TL;DR: The hypothesis explored in this review is that the use of a standardized approach to the functional preservation of the EBSLN can be facilitated by application of IONM resulting in improved preservation of voice following thyroidectomy or parathyroidectomy.
Abstract: Intraoperative neural monitoring (IONM) during thyroid surgery has gained widespread acceptance as an adjunct to the gold standard of visual identification of the recurrent laryngeal nerve (RLN). Contrary to routine dissection of the RLN, most surgeons tend to avoid rather than routinely expose and identify the external branch of the superior laryngeal nerve (EBSLN) during thyroidectomy or parathyroidectomy. IONM has the potential to be utilized for identification of the EBSLN and functional assessment of its integrity; therefore, IONM might contribute to voice preservation following thyroidectomy or parathyroidectomy. We reviewed the literature and the cumulative experience of the multidisciplinary International Neural Monitoring Study Group (INMSG) with IONM of the EBSLN. A systematic search of the MEDLINE database (from 1950 to the present) with predefined search terms (EBSLN, superior laryngeal nerve, stimulation, neuromonitoring, identification) was undertaken and supplemented by personal communication between members of the INMSG to identify relevant publications in the field. The hypothesis explored in this review is that the use of a standardized approach to the functional preservation of the EBSLN can be facilitated by application of IONM resulting in improved preservation of voice following thyroidectomy or parathyroidectomy. These guidelines are intended to improve the practice of neural monitoring of the EBSLN during thyroidectomy or parathyroidectomy and to optimize clinical utility of this technique based on available evidence and consensus of experts. Level of Evidence 5 Laryngoscope, 123:S1–S14, 2013

262 citations

Journal ArticleDOI
TL;DR: Hematic MRI and ultrasound are both useful in identifying heavy fat accumulation associated with nonalcoholic fatty liver disease and are superior to ultrasound in detecting and quantifying minor degrees of fatty metamorphosis in the liver.
Abstract: Purpose:The value of MRI and ultrasound in quantifying hepatic steatosis is assessed and the results compared with those obtained by liver biopsies.Methods:A total of 38 patients undergoing hepatic biopsy for a variety of liver diseases were recruited for this study. Hepatic fat morphology and sever

262 citations


Authors

Showing all 3778 results

NameH-indexPapersCitations
Jatin P. Shah11972545680
Harold G. Koenig9967846742
Chawnshang Chang9753435629
Richard J. K. Taylor91154343893
Martin R. Farlow8238126820
David A. D'Alessio8027222955
Dirk R. Larson7927124067
Andrzej Bartke7851622865
Michael Brenner7656422010
Arnulf Stenzl7379123285
Wolfgang H. Dillmann7220017595
Michael Bonkowski6627913851
Jacob E. Friedman6519112485
Richard Salvi6544716289
Russell Noyes6322912790
Network Information
Related Institutions (5)
Icahn School of Medicine at Mount Sinai
76K papers, 3.7M citations

95% related

Johns Hopkins University School of Medicine
79.2K papers, 4.7M citations

94% related

Baylor College of Medicine
94.8K papers, 5M citations

94% related

University of Texas Southwestern Medical Center
75.2K papers, 4.4M citations

94% related

Oregon Health & Science University
65.1K papers, 3.3M citations

94% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20237
202233
2021281
2020276
2019221
2018177