Institution
Southern Illinois University School of Medicine
Education•Springfield, Illinois, United States•
About: Southern Illinois University School of Medicine is a education organization based out in Springfield, Illinois, United States. It is known for research contribution in the topics: Population & Cancer. The organization has 3747 authors who have published 5977 publications receiving 209115 citations. The organization is also known as: SIU School of Medicine.
Topics: Population, Cancer, Ototoxicity, Receptor, Health care
Papers published on a yearly basis
Papers
More filters
TL;DR: A model for the CRP is described along with a critique of other models that have been suggested and the results of research that examines components of the process must be seen in relation to the overall process.
Abstract: Medical school teachers must have an accurate idea of the doctor's clinical reasoning process (CRP) in order to provide students with learning experiences and evaluations that will ensure their acquisition of an effective and efficient CRP It is difficult to derive this understanding from much that has been written on the subject It is important to recognize that clinical problems are ill-structured and that the doctor's reasoning is built around a temporal unfolding of information A model for the CRP is described along with a critique of other models that have been suggested The results of research that examines components of the process must be seen in relation to the overall process
249 citations
TL;DR: The results of this study suggest two possible mechanisms for deposition of collagen in keloid lesions in vivo: first, the growth of the lesions may result from a localized loss of control of the extracellular matrix production by fibroblasts; secondly, reduced degradation of the newly synthesized procollagen polypeptides may contribute to collagen deposition in some keloids.
248 citations
TL;DR: Ultrasound is a reliable adjuvant for the accurate and precise diagnosis of skin lesions and can detect lesions that are epidermal only or that measure less than 0.1 mm in depth.
Abstract: Background High variable-frequency ultrasound is a recently available technique capable of clearly defining skin layers and deeper structures that also provides local perfusion patterns obtained in real time. Objectives The aim of the study was to assess the performance of variable-frequency ultrasound in the evaluation of skin lesions. Methods We performed a retrospective study of 4338 skin ultrasound examinations in predominantly localized skin lesions, and in a group of 130 healthy controls. We determined ultrasound sensitivity, specificity, and statistical level of certainty, and compared ultrasound diagnoses with clinical diagnoses. Results Referring diagnosis was correct in 73% of the lesions, and addition of ultrasound increased correctness to 97% (P Limitations Ultrasound in its current version cannot detect lesions that are epidermal only or that measure less than 0.1 mm in depth. Conclusions Ultrasound is a reliable adjuvant for the accurate and precise diagnosis of skin lesions.
248 citations
TL;DR: Monitoring the pulsatile flow changes in the anterior cerebral arteries using Doppler ultrasound determined the cerebrovascular hemodynamic alterations in asphyxia and intracerebral-intraventricular hemorrhage, which indicate vasodilation and decreased resistance to blood flow in infants with respiratory distress and in those with IC-IVH.
246 citations
TL;DR: Results obtained in GH-related mutant mice provide striking examples of mutations of a single gene delaying aging, reducing age-related disease, and extending lifespan in a mammal and providing novel experimental systems for the study of mechanisms of aging.
Abstract: Growth hormone (GH) is a key determinant of postnatal growth and plays an important role in the control of metabolism and body composition. Surprisingly, deficiency in GH signaling delays aging and...
244 citations
Authors
Showing all 3778 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Jatin P. Shah | 119 | 725 | 45680 |
| Harold G. Koenig | 99 | 678 | 46742 |
| Chawnshang Chang | 97 | 534 | 35629 |
| Richard J. K. Taylor | 91 | 1543 | 43893 |
| Martin R. Farlow | 82 | 381 | 26820 |
| David A. D'Alessio | 80 | 272 | 22955 |
| Dirk R. Larson | 79 | 271 | 24067 |
| Andrzej Bartke | 78 | 516 | 22865 |
| Michael Brenner | 76 | 564 | 22010 |
| Arnulf Stenzl | 73 | 791 | 23285 |
| Wolfgang H. Dillmann | 72 | 200 | 17595 |
| Michael Bonkowski | 66 | 279 | 13851 |
| Jacob E. Friedman | 65 | 191 | 12485 |
| Richard Salvi | 65 | 447 | 16289 |
| Russell Noyes | 63 | 229 | 12790 |