Universal College

About: Universal College is a education organization based out in Las Piñas, Philippines. It is known for research contribution in the topics: Population & Health care. The organization has 567 authors who have published 450 publications receiving 1933 citations. The organization is also known as: Universal College of Nursing.

Data Security in cloud computing using Hierarchical CP-ABE scheme with scalability and flexibility

Abstract: Cloud computing has a major role in the development of commercial systems. It enables companies like Microsoft, Amazon, IBM and Google to deliver their services on a large scale to its users. A cloud service provider manages cloud computing based services and applications. For any organization a cloud service provider (CSP) is an entity which works within it. So it suffers from vulnerabilities associated with organization, including internal and external attacks. So its challenge to organization to secure a cloud service provider while providing quality of service. Attribute based encryption can be used to provide data security with Key policy attribute based encryption (KP-ABE) or ciphertext policy attribute based encryption (CP-ABE). But these schemes has lack of scalability and flexibility. Hierarchical CP-ABE scheme is proposed here to provide fine grained access control. Data security is achieved using encryption, authentication and authorization mechanisms. Attribute key generation is proposed for implementing authorization of users. The proposed system is prevented by SQL Injection attack.

Demographic and clinical profiles of hiv positive cases : a two-year study report from a tertiary teaching hospital

Abstract: The report on the pattern of demographic and clinical profiles of HIV positive persons in Nepal are scarce. Present study was carried out at the Universal College of Medical Sciences Teaching Hospital at Bhairahawa (UCMS-TH). Following group of patients, who attended our different OPDs for a period of two years (January 2001 to December 2002) were subjected to HIV tests: History of exposure to Commercial Sex Workers (CSW), history of travelling and working India/abroad, living single, driver/cleaner by profession, history of injection drug use (IDU), unexplained fever, diarrhoea and significant loss of weight for over a month, all cases of Sexually Transmitted Diseases (STDs), etc. A total of 43 HIV positive cases were detected during the period. Mode of transmission was as follows: 6 (13.9%) patients were injection drug users (IDU), one case (2.3%) transmitted through blood transfusion (BT), one patient (2.3%) was homosexual while heterosexual transmission was noted in 34 (79.1%) patients. Out of 23 injection drug users (IDUs) admitted during the period, 6 cases were detected positive for HIV infection. Applying ‘Expanded WHO Case Definition for AIDS Surveillance’, out of total 43 cases at least 28 (65%) cases could be detected as having suffering from clinical AIDS; 12 (27.7%) of them were suffering from pulmonary or extra-pulmonary tuberculosis. A significant percentage of these patients belonged to lower socio-economic class and many of them were mobile worker and contacted their illness while working in Indian metropolis in the past. ABSTRACT Key Words: HIV positive, Clinical AIDS, Nepal.

Efficacy and Cardiovascular Safety of GLP-1 Receptor Analogues

Abstract: Glucagon-like peptide- 1 receptor analogs (GLP-1RAs) are incretin mimetics with potent glucose-dependent insulinotropic action that translates to glycemic control in people with type- -2 diabetes mellitus (T2DM). These agents potentially have the ability to stimulate proliferation or prevent apoptosis of pancreatic β-cells, induce weight-loss and provide vascular benefits in patients with T2DM. Newer GLP-1RA, semaglutide has shown a robust reduction in HbA1c up to 1.5 - 1.8%. However, individual differences exist between the different GLP-1RAs, in terms of efficacy, pharmacokinetics, tolerability, and vascular protection. The potential of vascular protection offered by newer anti-diabetic agents has generated a lot of excitement in the field of diabetes, and to a large extent, is now driving treatment decisions. So far, six cardiovascular outcome trials of GLP-1 RAs have been published, analyzing lixisenatide (ELIXA), liraglutide (LEADER), semaglutide (SUSTAIN-6), long-acting exenatide (EXSCEL), dulaglutide (REWIND), and oral semaglutide (PIONEER 6) with a follow-up duration of 2-4 years. LEADER, REWIND and SUSTAIN-6 trials have demonstrated a reduction in rates of major adverse cardiovascular events with active GLP-1 RA treatment, but ELIXA, PIONEER 6 and EXSCEL, have been neutral. In this review, we discuss the available evidence from randomized controlled trials (RCTs) analyzing the cardiovascular effects of various GLP-1 RAs with the aim of comparing individual drugs. We have also summarized the general aspects of GLP-1RAs that can be applied in clinical practice.

Evaluation of salivary levels of visfatin in obese patients with chronic periodontitis

Abstract: Background: Visfatin, also known as nicotinamide phosphoribosyltransferase, is an adipokine implicated in obesity and plays an important role in regulating the defense and immune functions and is also suggested as a pro-inflammatory and immunomodulating marker for periodontitis. Hence, the aim of the present study was to assess the salivary levels of visfatin in obese patients with and without chronic periodontitis and nonobese healthy patients. Materials and Methods: A total of 45 patients were divided into: nonobese healthy (Group 1, n = 15, body mass index [BMI] ≤22.9 and waist circumference [WC]