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Institution

University of Central Florida

EducationOrlando, Florida, United States
About: University of Central Florida is a education organization based out in Orlando, Florida, United States. It is known for research contribution in the topics: Laser & Population. The organization has 18822 authors who have published 48679 publications receiving 1234422 citations. The organization is also known as: UCF.


Papers
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Journal ArticleDOI
TL;DR: The aim of this article is to review the different TEER measurement techniques and analyze their strengths and weaknesses, determine the significance of TEER in drug toxicity studies, and examine the various in vitro models and microfluidic organs-on-chips implementations using TEER measurements in some widely studied barrier models.
Abstract: Transepithelial/transendothelial electrical resistance (TEER) is a widely accepted quantitative technique to measure the integrity of tight junction dynamics in cell culture models of endothelial and epithelial monolayers. TEER values are strong indicators of the integrity of the cellular barriers before they are evaluated for transport of drugs or chemicals. TEER measurements can be performed in real time without cell damage and generally are based on measuring ohmic resistance or measuring impedance across a wide spectrum of frequencies. The measurements for various cell types have been reported with commercially available measurement systems and also with custom-built microfluidic implementations. Some of the barrier models that have been widely characterized using TEER include the blood–brain barrier (BBB), gastrointestinal (GI) tract, and pulmonary models. Variations in these values can arise due to factors such as temperature, medium formulation, and passage number of cells. The aim of this article ...

1,300 citations

Journal ArticleDOI
TL;DR: In this paper, a systematic study of the influence of scattering from impurities on the peculiar electronic properties of graphene is conducted by monitoring changes in electronic characteristics of initially clean graphene, by depositing potassium atoms onto its surface in ultrahigh vacuum.
Abstract: Valuable insight into the influence of scattering from impurities on the peculiar electronic properties of graphene are gained by a systematic study of how its conductivity changes with increasing concentration of potassium ions deposited on its surface. Since the initial demonstration of the ability to experimentally isolate a single graphene sheet1, a great deal of theoretical work has focused on explaining graphene’s unusual carrier-density-dependent conductivity σ(n), and its minimum value (σmin) of nearly twice the quantum unit of conductance (4e2/h) (refs 1, 2, 3, 4, 5, 6). Potential explanations for such behaviour include short-range disorder7,8,9,10, ‘ripples’ in graphene’s atomic structure11,12 and the presence of charged impurities7,8,13,14,15,16,17,18. Here, we conduct a systematic study of the last of these mechanisms, by monitoring changes in electronic characteristics of initially clean graphene19 as the density of charged impurities (nimp) is increased by depositing potassium atoms onto its surface in ultrahigh vacuum. At non-zero carrier density, charged-impurity scattering produces the widely observed linear dependence1,2,3,4,5,6 of σ(n). More significantly, we find that σmin occurs not at the carrier density that neutralizes nimp, but rather the carrier density at which the average impurity potential is zero15. As nimp increases, σmin initially falls to a minimum value near 4e2/h. This indicates that σmin in the present experimental samples1,2,3,4,5,6 is governed not by the physics of the Dirac point singularity20,21, but rather by carrier-density inhomogeneities induced by the potential of charged impurities6,8,14,15.

1,287 citations

Journal ArticleDOI
09 Aug 2017-Nature
TL;DR: Higher-order exceptional points are observed in a coupled cavity arrangement—specifically, a ternary, parity–time-symmetric photonic laser molecule—with a carefully tailored gain–loss distribution and it is found that the frequency response follows a cube-root dependence on induced perturbations in the refractive index.
Abstract: Non-Hermitian degeneracies, also known as exceptional points, have recently emerged as a new way to engineer the response of open physical systems, that is, those that interact with the environment. They correspond to points in parameter space at which the eigenvalues of the underlying system and the corresponding eigenvectors simultaneously coalesce. In optics, the abrupt nature of the phase transitions that are encountered around exceptional points has been shown to lead to many intriguing phenomena, such as loss-induced transparency, unidirectional invisibility, band merging, topological chirality and laser mode selectivity. Recently, it has been shown that the bifurcation properties of second-order non-Hermitian degeneracies can provide a means of enhancing the sensitivity (frequency shifts) of resonant optical structures to external perturbations. Of particular interest is the use of even higher-order exceptional points (greater than second order), which in principle could further amplify the effect of perturbations, leading to even greater sensitivity. Although a growing number of theoretical studies have been devoted to such higher-order degeneracies, their experimental demonstration in the optical domain has so far remained elusive. Here we report the observation of higher-order exceptional points in a coupled cavity arrangement-specifically, a ternary, parity-time-symmetric photonic laser molecule-with a carefully tailored gain-loss distribution. We study the system in the spectral domain and find that the frequency response associated with this system follows a cube-root dependence on induced perturbations in the refractive index. Our work paves the way for utilizing non-Hermitian degeneracies in fields including photonics, optomechanics, microwaves and atomic physics.

1,271 citations

Journal ArticleDOI
TL;DR: Factors related to the robot itself, specifically, its performance, had the greatest current association with trust, and environmental factors were moderately associated; there was little evidence for effects of human-related factors.
Abstract: Objective: We evaluate and quantify the effects of human, robot, and environmental factors on perceived trust in human-robot interaction (HRI)Background: To date, reviews of trust in HRI have been

1,255 citations

Journal ArticleDOI
TL;DR: A thorough, sophisticated literature review is the foundation and inspiration for substantial, useful research in education research as discussed by the authors, which is a prerequisite for increased methodological sophistication and for improving the usefulness of education research.
Abstract: A thorough, sophisticated literature review is the foundation and inspiration for substantial, useful research. The complex nature of education research demands such thorough, sophisticated reviews. Although doctoral education is a key means for improving education research, the literature has given short shrift to the dissertation literature review. This article suggests criteria to evaluate the quality of dissertation literature reviews and reports a study that examined dissertations at three universities. Acquiring the skills and knowledge required to be education scholars, able to analyze and synthesize the research in a field of specialization, should be the focal, integrative activity of predissertation doctoral education. Such scholarship is a prerequisite for increased methodological sophistication and for improving the usefulness of education research.

1,230 citations


Authors

Showing all 19051 results

NameH-indexPapersCitations
Gang Chen1673372149819
Kevin M. Huffenberger13840293452
Eduardo Salas12971162259
Akihisa Inoue126265293980
Allan H. MacDonald11992656221
Hagop S. Akiskal11856550869
Richard P. Van Duyne11640979671
Jun Wang106103149206
Mubarak Shah10661456738
Larry L. Hench10349155633
Michael Walsh10296342231
Wei Liu102292765228
Demetrios N. Christodoulides10070451093
Paul E. Spector9932552843
Eric A. Hoffman9980936891
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202398
2022371
20213,429
20203,546
20193,315
20183,094