Showing papers in "Research in Virology in 1990"

TL;DR: Tetracycline analogs were evaluated for anti-HIV activity in CEM cells; minocycline and doxycycline were the most active of these in inhibiting the virus-induced cytopathic effect between 7 and 14 days post-infection as mentioned in this paper.

TL;DR: Comparisons using DNA/DNA hybridization, DNA base composition, restriction endonuclease DNA analysis, cellular protein patterns and metabolism inhibition serologic procedures confirm that the organism previously designated as "Mycoplasma incognitus" (Mi) is indeed very closely related to strains of M. fermentans.

TL;DR: This work has used multiple alignment computer programs to align and hierarchically cluster the conserved amino acid "signature" sequences found in the replication-associated proteins of all plant RNA viruses sequenced so far.

TL;DR: Because of the very important role of the mononuclear phagocyte system in the immunopathogenesis of HIV infection, a culture system for in vitro studies of infection of monocytes/macrophages with HIV was developed.

TL;DR: To assess the role of HCV in the development of both cirrhosis and primary liver cancer, a confirmation test is needed.

TL;DR: The findings emphasize the need for continuous surveillance of HRV infections in different geographic areas of the world in order to detect the appearance of new strains early and to adopt adequate strategies for vaccine preparation and administration.

TL;DR: Results indicate that liver cells, including Kupffer cells, might be infected by HIV1.

TL;DR: Analysis by polyacrylamide gel electrophoresis of nucleic acid extracts from different peach samples, healthy or infected with the peach latent mosaic (PLM) disease, demonstrated the association of this disease with an RNA exhibiting the electrophoretic properties typical of circular viroid molecules.

TL;DR: This is the first time that direct evidence is given for the involvement of a viral satellite in a crop disease of epidemic scale and the possible molecular interrelationships between plant, virus, satellite and other factors that influence the satellite-induced symptom modulation underlying a catastrophe are discussed.

TL;DR: Imbalances of T-cell subpopulations appear to be mainly responsible for the progressive impairment of proliferation and differentiation of bone marrow progenitor cells observed in HIV-infected individuals.

TL;DR: Sera collected 2 years after infection revealed higher IgG ELISA OD readings than convalescent sera, and very high values were still detectable 10 to 20 years postinfection, which is useful for the testing of immunity and in seroepidemiological studies.

TL;DR: It is demonstrated that the cells constituting the largest fraction of fixed macrophages in the body may be infected by HIV, thereby suggesting that the Kupffer cells may play a role in the physiopathology of the disease, namely as a reservoir for the virus.

TL;DR: It was concluded that HIV1-infected reticular cells may be disturbed in their ability to produce factors responsible for the short-range regulation of haemopoietic activity.

TL;DR: Cette technique qui permet la synthese, de facon tres simple, de quantites importantes d'ADN marque, a ete appliquee pour obtenir des sondes froides pour le virus d'Epstein-Barr & Chlamydia trachomatis.

TL;DR: By flow cytometry, it is shown that macrophages bind and internalize mannosylated and 6-phosphomannosylated ligands in acidic compartments.

TL;DR: The DNA of 60 adenovirus type 8 (AV8) isolates was analysed by 6 endonucleases and revealed 6 different genome types, thus implying that the variability of AV8 is relatively low.

TL;DR: The data implicate the loss of F protein as a cause of reduced immunogenicity of further attenuated measles vaccines.

TL;DR: Evidence has been generated that M1 protein inhibits the steps of vRNA transcription initiation and reinitiation more effectively than that of RNA chain elongation, implying that M 1 protein binds to the ribonucleoprotein complex (RNP) through NP.

TL;DR: A serological study of human herpesvirus-6 (HHV-6) infection was performed by means of immunofluorescence assay on fixed HHV- 6-infected cells and no serological cross-reactivity was observed between HHv-6 and other herpesviruses, suggesting that the HH V-6 ACIF test was quite specific.

TL;DR: A reduced panel of 4 anti-nucleocapsid monoclonal antibodies (mAb) was set up to distinguish viruses of terrestrial mammal origin from viruses of bat origin in Europe.

TL;DR: A case of acute regressive meningoradiculitis concomitant with HIV1 primoinfection is reported, with the regressive demyelinating-type process confirmed by electromyographic studies.

TL;DR: La frequence relatives des serotypes des rotavirus a ete determinee pour 539 echantillons positifs de selles d'enfants diarrheiques, a Yamagata, au cours de la periode de janvier 1986 a septembre 1989.

TL;DR: HIV-specific alveolar T-lymphocyte cytolytic activity decreased with progression towards AIDS as shown by studies of a series of 40 patients, suggesting that local tissue injury could result from the in vivo immune conflict between alveolars HIV-specific CTL and HIV-infected macrophages.

TL;DR: Three West Nile virus strains isolated in Bangui, Central African Republic from patients with hepatitis were analysed comparatively with the prototype WN virus strain and 7 WN strains previously isolated from birds, mosquitoes and ticks, concluding that the same virus subtype may have been the cause of different infection patterns.

TL;DR: The experiments established that CARNA-5 biological expression studies in CMV-infected tomato have to take into account the helper virus satellite replication support function, which may be a primary codeterminant of quantitative or qualitative differences in the symptom modulation observed.

TL;DR: There was ample evidence of impairment of macrophage activation, accompanied by decreased expression of functional markers and an enhanced reactivity with antibodies against S100 protein.

TL;DR: Replacing nick-translated DNA probes by in vitro transcribed complementary RNA (cRNA) probes considerably increased the sensitivity of dot-blot detection tests of potato spindle tuber viroid and chrysanthemum stunt viroid.

TL;DR: An experimental system that permits quantification of translational errors in vivo that consists of a family of expression vectors carrying different mutated versions of the luc gene as reporter, which can be used to analyse the influence of structural and external factors on translational ambiguity in both mammalian cells and bacteria.

TL;DR: Samples of nasopharyngeal secretion from 100 infants and small children admitted for acute respiratory disease during the period from January to March 1989 were examined for the presence of influenza A virus.

TL;DR: Results show that the demonstration of lacrimal HIV-specific IgA may help to distinguish between truly infected children and those whose HIV antibodies are passively transferred from the mother.