Journal ArticleDOI
3d Transition Metals for C-H Activation.
Parthasarathy Gandeepan,Thomas Müller,Daniel Zell,Gianpiero Cera,Svenja Warratz,Lutz Ackermann +5 more
Reads0
Chats0
TLDR
A comprehensive overview on first row transition metal catalysts for C-H activation until summer 2018 is provided.Abstract:
C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with notable applications to material sciences, crop protection, drug discovery, and pharmaceutical industries, among others. Despite major advances, the vast majority of these C–H functionalizations required precious 4d or 5d transition metal catalysts. Given the cost-effective and sustainable nature of earth-abundant first row transition metals, the development of less toxic, inexpensive 3d metal catalysts for C–H activation has gained considerable recent momentum as a significantly more environmentally-benign and economically-attractive alternative. Herein, we provide a comprehensive overview on first row transition metal catalysts for C–H activation until summer 2018.read more
Citations
More filters
Journal ArticleDOI
Tris-NHC-propagated self-supported polymer-based Pd catalysts for heterogeneous C–H functionalization
TL;DR: In this article, three-dimensional propagated imidazolium-containing mesoporous coordination polymer and organic polymer-based platforms were successfully exploited to develop single-site heterogenized Pd-NHC catalysts for oxidative arene/hetero-arene C-H functionalization reactions.
Journal ArticleDOI
Oxidative C-H/N-H Annulation of Aromatic Amides with Dialkyl Malonates: Access to Isoindolinones and Dihydrobenzoindoles.
TL;DR: A copper-mediated oxidative C-H/N-H annulation of aromatic amides with dialkyl malonates has been presented to afford synthetically valuable dihydrobenzoindoles and isoindolinones.
Journal ArticleDOI
Early transition metal complexes for direct C H bond functionalization of heteroatom-containing organic compounds
TL;DR: In this paper , the authors focus on the unique reactivity of early transition metal complexes toward the activation of C(sp2)H bonds of heteroatom-containing organic compounds, such as pyridine derivatives and alkylamines.
Journal ArticleDOI
Iron-catalysed alkene and heteroarene H/D exchange by reversible protonation of iron-hydride intermediates
Luke Britton,Jamie H. Docherty,Jan Sklyaruk,J. D. Cooney,Gary S. Nichol,Andrew P. Dominey,Stephen P. Thomas +6 more
TL;DR: The ability to produce, isolate and characterise the organometallic products arising from C–H activation presents a basis for future discovery and development.
Journal ArticleDOI
Cobalt-catalyzed C–H bond functionalization using traceless directing group
TL;DR: In this article, a traceless directing group (TDG) strategy has been used for the site selective and atom-economic construction of C-C and C-Heteroatom bonds.
References
More filters
Journal ArticleDOI
Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions
TL;DR: This is the first comprehensive review encompassing the large body of work in this field over the past 5 years, and will focus specifically on ligand-directed C–H functionalization reactions catalyzed by palladium.
Journal ArticleDOI
Fluorine in Pharmaceuticals: Looking Beyond Intuition.
TL;DR: Experimental progress in exploration of the specific influence of carbon-fluorine single bonds on docking interactions is reviewed and complementary analysis based on comprehensive searches in the Cambridge Structural Database and the Protein Data Bank is added.
Book ChapterDOI
Heavy metal toxicity and the environment.
TL;DR: This review provides an analysis of arsenic, cadmium, chromium, lead, and mercury's environmental occurrence, production and use, potential for human exposure, and molecular mechanisms of toxicity, genotoxicity, and carcinogenicity.
Journal ArticleDOI
Understanding TiO2 photocatalysis: mechanisms and materials.
Jenny Schneider,Masaya Matsuoka,Masato Takeuchi,Jinlong Zhang,Yu Horiuchi,Masakazu Anpo,Detlef W. Bahnemann +6 more
TL;DR: This paper presents a meta-analyses of the chiral stationary phase transition of Na6(CO3)(SO4)2, Na2SO4, and Na2CO3 of the Na2O/Na2O 2 mixture at the stationary phase and shows clear patterns in the response of these two materials to each other.
Journal ArticleDOI
Organic Photoredox Catalysis
TL;DR: An overview of the basic photophysics and electron transfer theory is presented in order to provide a comprehensive guide for employing this class of catalysts in photoredox manifolds.