Journal ArticleDOI
3d Transition Metals for C-H Activation.
Parthasarathy Gandeepan,Thomas Müller,Daniel Zell,Gianpiero Cera,Svenja Warratz,Lutz Ackermann +5 more
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TLDR
A comprehensive overview on first row transition metal catalysts for C-H activation until summer 2018 is provided.Abstract:
C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with notable applications to material sciences, crop protection, drug discovery, and pharmaceutical industries, among others. Despite major advances, the vast majority of these C–H functionalizations required precious 4d or 5d transition metal catalysts. Given the cost-effective and sustainable nature of earth-abundant first row transition metals, the development of less toxic, inexpensive 3d metal catalysts for C–H activation has gained considerable recent momentum as a significantly more environmentally-benign and economically-attractive alternative. Herein, we provide a comprehensive overview on first row transition metal catalysts for C–H activation until summer 2018.read more
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Journal ArticleDOI
Cobalt-catalyzed carbonylation of the C–H bond
TL;DR: This review summarizes the C- H bond carbonylation methodologies using the cobalt-catalyzed C-H bond functionalization approach.
Journal ArticleDOI
Cobaltaelectro-catalyzed C–H activation for resource-economical molecular syntheses
Cong Tian,Tjark H. Meyer,Maximilian Stangier,Uttam Dhawa,Karsten Rauch,Lars H. Finger,Lutz Ackermann +6 more
TL;DR: This protocol provides a general method for cobaltaelectro-catalyzed C–H activations of benzamides using anodic oxidation, which obviates the need for a chemical oxidant and uses 10–20% of a more environmentally benign, inexpensive catalyst.
Journal ArticleDOI
Recent Advancements in Allylic C(sp3)–H Functionalization of Olefins Catalyzed by Rh(III) or Ir(III) Complexes
Journal ArticleDOI
Pd(II)-Catalyzed C-H Acylation of (Hetero)arenes-Recent Advances.
TL;DR: Di(hetero)aryl ketones are important motifs present in natural products, pharmaceuticals or agrochemicals, and different directing groups and acyl sources are being studied for this purpose, although further development is required to face mainly selectivity problems in order to be applied in the synthesis of more complex molecules.
Journal ArticleDOI
Redox-Active α-Diimine Complexes of Early Transition Metals: From Bonding to Catalysis
TL;DR: In this article, it is shown that early transition metals favorably adopt their highest oxidation state with d0 configuration, and they have been interested in early transition metal complexes bearing redox properties.
References
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Journal ArticleDOI
Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions
TL;DR: This is the first comprehensive review encompassing the large body of work in this field over the past 5 years, and will focus specifically on ligand-directed C–H functionalization reactions catalyzed by palladium.
Journal ArticleDOI
Fluorine in Pharmaceuticals: Looking Beyond Intuition.
TL;DR: Experimental progress in exploration of the specific influence of carbon-fluorine single bonds on docking interactions is reviewed and complementary analysis based on comprehensive searches in the Cambridge Structural Database and the Protein Data Bank is added.
Book ChapterDOI
Heavy metal toxicity and the environment.
TL;DR: This review provides an analysis of arsenic, cadmium, chromium, lead, and mercury's environmental occurrence, production and use, potential for human exposure, and molecular mechanisms of toxicity, genotoxicity, and carcinogenicity.
Journal ArticleDOI
Understanding TiO2 photocatalysis: mechanisms and materials.
Jenny Schneider,Masaya Matsuoka,Masato Takeuchi,Jinlong Zhang,Yu Horiuchi,Masakazu Anpo,Detlef W. Bahnemann +6 more
TL;DR: This paper presents a meta-analyses of the chiral stationary phase transition of Na6(CO3)(SO4)2, Na2SO4, and Na2CO3 of the Na2O/Na2O 2 mixture at the stationary phase and shows clear patterns in the response of these two materials to each other.
Journal ArticleDOI
Organic Photoredox Catalysis
TL;DR: An overview of the basic photophysics and electron transfer theory is presented in order to provide a comprehensive guide for employing this class of catalysts in photoredox manifolds.