Journal ArticleDOI
3d Transition Metals for C-H Activation.
Parthasarathy Gandeepan,Thomas Müller,Daniel Zell,Gianpiero Cera,Svenja Warratz,Lutz Ackermann +5 more
Reads0
Chats0
TLDR
A comprehensive overview on first row transition metal catalysts for C-H activation until summer 2018 is provided.Abstract:
C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with notable applications to material sciences, crop protection, drug discovery, and pharmaceutical industries, among others. Despite major advances, the vast majority of these C–H functionalizations required precious 4d or 5d transition metal catalysts. Given the cost-effective and sustainable nature of earth-abundant first row transition metals, the development of less toxic, inexpensive 3d metal catalysts for C–H activation has gained considerable recent momentum as a significantly more environmentally-benign and economically-attractive alternative. Herein, we provide a comprehensive overview on first row transition metal catalysts for C–H activation until summer 2018.read more
Citations
More filters
Journal ArticleDOI
Cobalta-Electrocatalyzed C–H Allylation with Unactivated Alkenes
TL;DR: In contrast to precious palladium, rhodium, iridium, and ruthenium catalysts that are lim... as discussed by the authors, cobalt catalysis enabled the electrochemical C-H allylation with nonactivated alkenes.
Journal ArticleDOI
Cobalt-catalyzed C8-Dienylation of Quinoline-N-oxides
TL;DR: An efficient Cp*Co(III)-catalyzed C-8 dienylation of quinoline- N -oxides was achieved employing allenes bearing leaving groups at the α -position as the dienelating agents, featuring high stereoselectivity, mild conditions, and good functional group tolerance.
Journal ArticleDOI
Recent Development on Cp*Ir(III)-Catalyzed C−H Bond Functionalization
TL;DR: This work presents Cp*Ir(III) complexes, which have exhibited versatile reactivity towards the selective conversion of C−H bonds, with key features that include the use of readily transformable raw materials, great selectivity, high efficiency, mild reaction conditions and they enable late‐stage modification of complex molecules.
Journal ArticleDOI
Chromium(II)-Catalyzed Diastereoselective and Chemoselective Csp2-Csp3 Cross-Couplings Using Organomagnesium Reagents.
TL;DR: Detailed mechanistic studies suggest that the in situ generated low-valent chromium(I) species might be the active catalyst for these Csp2‒Csp3 cross-coupling products in good yields and high diastereoselectivity.
Journal ArticleDOI
Copper-Catalyzed Regioselective C–H Amination of Phenol Derivatives with Assistance of Phenanthroline-Based Bidentate Auxiliary
TL;DR: A copper-catalyzed regioselective direct amination of phenol derivatives with diarylamines via phenanthroline-based bidentate auxiliary-directed C–H cleavage has been developed and can be easily attached, detached, and recycled.
References
More filters
Journal ArticleDOI
Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions
TL;DR: This is the first comprehensive review encompassing the large body of work in this field over the past 5 years, and will focus specifically on ligand-directed C–H functionalization reactions catalyzed by palladium.
Journal ArticleDOI
Fluorine in Pharmaceuticals: Looking Beyond Intuition.
TL;DR: Experimental progress in exploration of the specific influence of carbon-fluorine single bonds on docking interactions is reviewed and complementary analysis based on comprehensive searches in the Cambridge Structural Database and the Protein Data Bank is added.
Book ChapterDOI
Heavy metal toxicity and the environment.
TL;DR: This review provides an analysis of arsenic, cadmium, chromium, lead, and mercury's environmental occurrence, production and use, potential for human exposure, and molecular mechanisms of toxicity, genotoxicity, and carcinogenicity.
Journal ArticleDOI
Understanding TiO2 photocatalysis: mechanisms and materials.
Jenny Schneider,Masaya Matsuoka,Masato Takeuchi,Jinlong Zhang,Yu Horiuchi,Masakazu Anpo,Detlef W. Bahnemann +6 more
TL;DR: This paper presents a meta-analyses of the chiral stationary phase transition of Na6(CO3)(SO4)2, Na2SO4, and Na2CO3 of the Na2O/Na2O 2 mixture at the stationary phase and shows clear patterns in the response of these two materials to each other.
Journal ArticleDOI
Organic Photoredox Catalysis
TL;DR: An overview of the basic photophysics and electron transfer theory is presented in order to provide a comprehensive guide for employing this class of catalysts in photoredox manifolds.