A Brief History of Long-Term Potentiation.
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TLDR
The rich history of LTP is reviewed, which provides a compelling cellular model for learning and memory and shows how the pace of discovery is remarkable.About:
This article is published in Neuron.The article was published on 2017-01-18 and is currently open access. It has received 553 citations till now.read more
Citations
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The Microbiota-Gut-Brain Axis
John F. Cryan,Kenneth J. O’Riordan,Caitlin S. M. Cowan,Kiran V. Sandhu,Thomaz F.S. Bastiaanssen,Marcus Boehme,Martín Gabriel Codagnone,Sofia Cussotto,Christine Fülling,Anna V. Golubeva,Katherine E. Guzzetta,Minal Jaggar,Caitriona M. Long-Smith,Joshua M. Lyte,Jason A. Martin,Alicia Molinero-Perez,Gerard M. Moloney,Emanuela Morelli,Enrique Morillas,Rory C. O'Connor,Joana S Cruz-Pereira,Veronica L. Peterson,Kieran Rea,Nathaniel L. Ritz,Eoin Sherwin,Simon Spichak,Emily M. Teichman,Marcel van de Wouw,Ana Paula Ventura-Silva,Shauna E. Wallace-Fitzsimons,Niall P. Hyland,Gerard Clarke,Timothy G. Dinan +32 more
TL;DR: Future studies will focus on understanding the mechanisms underlying the microbiota-gut-brain axis and attempt to elucidate microbial-based intervention and therapeutic strategies for neuropsychiatric disorders.
Journal ArticleDOI
Towards an Understanding of Synapse Formation.
TL;DR: It is proposed that engagement of multifarious synaptic CAMs produces parallel trans-synaptic signals that mediate the establishment, organization, and plasticity of synapses, thereby controlling information processing by neural circuits.
Journal ArticleDOI
The Mechanisms and Functions of Synaptic Facilitation.
Skyler L. Jackman,Wade G. Regehr +1 more
TL;DR: The ability of the brain to store and process information relies on changing the strength of connections between neurons as discussed by the authors, which is a form of short-term plasticity that enhances synaptic transmission for less than a second.
Journal ArticleDOI
Hippocampal LTP and contextual learning require surface diffusion of AMPA receptors
Andrew C. Penn,Chun-Lei Zhang,Chun-Lei Zhang,François Georges,François Georges,L. Royer,L. Royer,L. Royer,Christelle Breillat,Christelle Breillat,Eric Hosy,Eric Hosy,Jennifer D. Petersen,Jennifer D. Petersen,Yann Humeau,Yann Humeau,Daniel Choquet,Daniel Choquet +17 more
TL;DR: Interference with AMPAR surface diffusion markedly impairs synaptic potentiation of Schaffer collaterals and commissural inputs to the CA1 area of the mouse hippocampus in cultured slices, acute slices and in vivo, providing a direct demonstration that the recruitment of new receptors to synapses by surface diffusion is a critical mechanism for the expression of LTP and hippocampal learning.
Journal ArticleDOI
Transcellular Nanoalignment of Synaptic Function.
TL;DR: The organization of each compartment is described and it is proposed that this architecture may allow for precise synaptic information exchange and may be modulated to contribute to the remarkable plasticity of brain function.
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Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path.
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