A critical review: vitamin b deficiency and nervous disease.
C. D. Aring,Tom Douglas Spies +1 more
TLDR
The artificial synthesis of a number of the components of the vitamin B complex has made available pure crystalline material in large amounts for clinical research, and thus a milestone in the history of these affections has been passed.Abstract:
AFFECTIONS of the nervous system which result from inadequate nutrition have assumed an increasingly important position through the rapid accumulation of clinical, experimental, and pathological data. The artificial synthesis of a number of the components of the vitamin B complex has made available pure crystalline material in large amounts for clinical research, and thus a milestone in the history of these affections has been passed. It now seems appropriate to review and summarize the knowledge of these important substances. To evaluate the status of a nutritional deficiency in man is difficult. As a rule the patient induces his own disease and provides a deficiency that is not quantitatively measurable, but frequently clinical and laboratory evaluations are attempted. Both the laboratory method and the clinical method have certain advantages. Mice are not yet men and until they are the work coming -from the study of human beings is essential. Since the experience of investigators working with animals may often point the way for clinical research, we have interspersed in this review a few of the pertinent studies on the effect of nutritional deficiency on the nervous system of animals. A scheme for illustrating the multiple factors of the vitamin B complex is given in Fig. 1. To date the following portions of the vitamin B complex have been isolated and synthesized in amounts sufficient to allow for clinical trial: thiamin hydrochloride, nicotinic acid, riboflavin, and 2-methyl, 3-hydroxy, 4, 5-di (hydroxymethyl) pyridine. The deficiencies of these substances as they apply to the nervous system of man will be discussed briefly.read more
Citations
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Syndrome of inappropriate antidiuretic hormone secretion and cerebral/renal salt wasting syndrome: similarities and differences
Ji Young Oh,Jae Il Shin +1 more
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A Neural Basis for the Acquired Capability for Suicide.
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Origin of radiation resistance in multi-principal element alloys
Hyeon-Seok Do,Byeong-Joo Lee +1 more
TL;DR: The origin of the slower radiation damage accumulation and the higher radiation damage tolerance in the CoCrFeMnNi HEA is discussed.
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Jaclyn Leigh Cann,Anthony De Luca,David C. Dunand,David Dye,Daniel B. Miracle,Hyun Seok Oh,Elsa Olivetti,Tresa M. Pollock,Warren J. Poole,Rui Yang,Cemal Cem Tasan +10 more
TL;DR: In this paper, the authors discuss the most urgent sustainability challenges that can be addressed with alloy design, to help orchestrate the increasing interest in metallurgical research to focus on these most critical challenges.
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Delayed Establishment of Gut Microbiota in Infants Delivered by Cesarean Section.
Gyungcheon Kim,Jaewoong Bae,Mi Jin Kim,Hyeji Kwon,Gwoncheol Park,Seok-jin Kim,Yon Ho Choe,Jisook Kim,Sook-Hyun Park,Byung-Ho Choe,Hakdong Shin,Ben Kang +11 more
TL;DR: Investigating the early gut microbiota of Korean newborns receiving the same postpartum care services for two weeks after birth by delivery mode confirmed that delivery mode is the major determinant of neonatal intestinal microbiome establishment and provides a profile of microbiota perturbations in CS infants.
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