Journal ArticleDOI
A Fluorescent Sensor for Dual-Channel Discrimination between Phosgene and a Nerve-Gas Mimic
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TLDR
A o-phenylenediamine-pyronin linked dye that is capable of both fluorogenic and colorimetric discrimination between phosgene and the prototypical nerve-agent mimic, diethyl chlorophosphate (DCP) in the solution or gas phase is designed.Abstract:
The ability to analyze highly toxic chemical warfare agents (CWAs) and related chemicals in a rapid and precise manner is essential in order to alleviate serious threats to humankind and public security caused by unexpected terrorist attacks and industrial accidents. In this investigation, we designed a o-phenylenediamine-pyronin linked dye that is capable of both fluorogenic and colorimetric discrimination between phosgene and the prototypical nerve-agent mimic, diethyl chlorophosphate (DCP) in the solution or gas phase. Moreover, this dye has been used to construct a portable kit that can be employed for real-time monitoring of DCP and phosgene in the field, both in a discriminatory manner, and in a simple and safe way.read more
Citations
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Journal ArticleDOI
Functional Synthetic Probes for Selective Targeting and Multi-analyte Detection and Imaging
Yongkang Yue,Fangjun Huo,Fangqin Cheng,Xijing Zhu,Tendai Mafireyi,Robert M. Strongin,Caixia Yin +6 more
TL;DR: This review focuses on recent innovations in probe design, detection mechanisms and the investigation of biological processes and the ongoing development of fluorescent probes to enable deeper insight into the physiology of bioactive analytes.
Journal ArticleDOI
Recent Advances in the Development of Chromophore-Based Chemosensors for Nerve Agents and Phosgene
Liyan Chen,Di Wu,Juyoung Yoon +2 more
TL;DR: This review describes in a comprehensive manner recent progress that has been made on the development of chromophore-based chemosensors for detecting nerve agents (mimic) and phosgene.
Journal ArticleDOI
Recent progress in fluorescent probes for detection of carbonyl species: Formaldehyde, carbon monoxide and phosgene
TL;DR: In this paper, the most significant developments in fluorescent probes for the detection of the carbonyl species formaldehyde, carbon monoxide and phosgene in recent years, with a special emphasis on their mechanisms and applications.
Journal ArticleDOI
Effective Strategy for Colorimetric and Fluorescence Sensing of Phosgene Based on Small Organic Dyes and Nanofiber Platforms.
Ying Hu,Liyan Chen,Hyeseung Jung,Yiying Zeng,Songyi Lee,K.M.K. Swamy,Xin Zhou,Myung Hwa Kim,Juyoung Yoon +8 more
TL;DR: Three o-phenylendiamine derivatives, containing 4-chloro-7-nitrobenzo[c][1,2,5]oxadiazole, rhodamine, and 1,8-naphthalimide moieties, were prepared and tested as phosgene chemosensors and display distinct color and fluorescence changes upon exposure to phosGene even in the solid state.
Journal ArticleDOI
BODIPY-Based Fluorescent Sensor for the Recognization of Phosgene in Solutions and in Gas Phase
TL;DR: A highly selective fluorescent sensor o-Pab for phosgene with a BODIPY unit as a fluorophore and o-phenylenediamine as a reactive site is constructed and excellent discrimination of o- Pab has been demonstrated to be due to the difference in highly reactive and bifunctional phosGene relative to its substitutes.
References
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Journal ArticleDOI
Selective chromo-fluorogenic detection of DFP (a Sarin and Soman mimic) and DCNP (a Tabun mimic) with a unique probe based on a boron dipyrromethene (BODIPY) dye
Andrea Barba-Bon,Ana M. Costero,Ana M. Costero,Salvador Gil,Salvador Gil,Ramón Martínez-Máñez,Félix Sancenón +6 more
TL;DR: P4 is the first probe capable of colorimetrically differentiating between a Tabun mimic (DCNP) and a Sarin and Soman mimic (DFP), and was able to discriminate between DFP and DCNP with remarkable sensitivity.
Journal ArticleDOI
Ratiometric double channel borondipyrromethene based chemodosimeter for the selective detection of nerve agent mimics
TL;DR: In this paper, a new chromo-fluorogenic probe based on the borondipyrromethene dye has been synthesized, which was attached to a sensing unit for the diethylcyanophosphonate and di-isopropylfluorophosphate detection.
Book ChapterDOI
Chapter 25 – Phosgene
TL;DR: Although there are no chronic animal data, subchronic studies indicate little accumulation of phosgene or increased severity of lesions with continuous exposure, which shows a steep exposure–response curve for pulmonary edema and mortality.
Journal ArticleDOI
Synthesis of new cyclic aromatic carbene ligands bearing remote amino groups and their palladium(II) complexes
TL;DR: New cyclic aromatic carbene ligands bearing remote amino groups were developed and the oxidative addition of Pd(0) into the chloride precursors yielded the corresponding PD(II) complexes whose carbenes ligand was demonstrated to have stronger donor ability than classical NHCs.