Journal ArticleDOI
A Fluorescent Sensor for Dual-Channel Discrimination between Phosgene and a Nerve-Gas Mimic
Reads0
Chats0
TLDR
A o-phenylenediamine-pyronin linked dye that is capable of both fluorogenic and colorimetric discrimination between phosgene and the prototypical nerve-agent mimic, diethyl chlorophosphate (DCP) in the solution or gas phase is designed.Abstract:
The ability to analyze highly toxic chemical warfare agents (CWAs) and related chemicals in a rapid and precise manner is essential in order to alleviate serious threats to humankind and public security caused by unexpected terrorist attacks and industrial accidents. In this investigation, we designed a o-phenylenediamine-pyronin linked dye that is capable of both fluorogenic and colorimetric discrimination between phosgene and the prototypical nerve-agent mimic, diethyl chlorophosphate (DCP) in the solution or gas phase. Moreover, this dye has been used to construct a portable kit that can be employed for real-time monitoring of DCP and phosgene in the field, both in a discriminatory manner, and in a simple and safe way.read more
Citations
More filters
Journal ArticleDOI
Fluorescent Chemosensor for Selective Detection of Phosgene in Solutions and in Gas Phase
TL;DR: A highly selective fluorescent probe constructed through o-phenylenediamine covalently linking to coumarin (o-Pac), which can respond to phosgene in turn-on fluorescence mode, which exhibits good selectivity to phOSgene over triphosgenes and various acyl chlorides.
Journal ArticleDOI
An ESIPT-Based Fluorescence Probe for Colorimetric, Ratiometric, and Selective Detection of Phosgene in Solutions and the Gas Phase.
TL;DR: A colorimetric and ratiometric fluorescence probe 1 for phosgene has been developed based on an ESIPT process as mentioned in this paper, which can be easily observed by the naked eye.
Journal ArticleDOI
A Single Fluorescent Chemosensor for Simultaneous Discriminative Detection of Gaseous Phosgene and a Nerve Agent Mimic.
TL;DR: A fluorescent chemosensor has been developed for discriminative detection of phosgene and a nerve agent mimic diethyl chlorophosphate (DCP), which was comprised of an anthracene-carboxyimide fluorophore and o-phenylenediamine reaction site.
Journal ArticleDOI
A BODIPY-Based Fluorescent Probe for Detection of Subnanomolar Phosgene with Rapid Response and High Selectivity
TL;DR: A new type of phosgene probe with a limit of detection down to 0.12 nM, response time of less than 1.5 s, and high selectivity over other similarly reactive toxic chemicals was developed using ethylenediamine as the recognition moiety and 8-substituted BODIPY unit as the fluorescence signaling component.
Journal ArticleDOI
A ratiometric fluorescent chemosensor for selective and visual detection of phosgene in solutions and in the gas phase
TL;DR: A ratiometric fluorescent chemosensor, Phos-1, was constructed with 4,5-diaminonaphthalimide as a fluorophore for selective and visual detection of phosgene.
References
More filters
Journal ArticleDOI
New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging
TL;DR: Although MRI, US, and x-ray CT are often listed as molecular imaging modalities, in truth, radionuclide and optical imaging are the most practical modalities for molecular imaging, because of their sensitivity and the specificity for target detection.
Journal ArticleDOI
Prognostic factors for local recurrence, metastasis, and survival rates in squamous cell carcinoma of the skin, ear, and lip : implications for treatment modality selection
TL;DR: All studies since 1940 on the prognosis of squamous cell carcinoma of the skin and lip are reviewed, finding local recurrences occur less frequently when SCC is treated by Mohs micrographic surgery.
Journal ArticleDOI
Decontamination of chemical warfare agents
Journal ArticleDOI
Dissolution of cholesterol gallstones by chenodeoxycholic acid.
TL;DR: Chenodeoxycholic acid may offer medical treatment for cholesterol cholelithiasis in man and the ratio of bile acids and lecithin to cholesterol in bile increased in all patients.
Journal ArticleDOI
Fluorescent Detection of Chemical Warfare Agents: Functional Group Specific Ratiometric Chemosensors
Shi-Wei Zhang,Timothy M. Swager +1 more
TL;DR: Indicators providing highly sensitive and functional group specific fluorescent response to diisopropyl fluorophosphate (DFP, a nerve gas (G-agent) simulant) are reported.