Journal ArticleDOI
A Fluorescent Sensor for Dual-Channel Discrimination between Phosgene and a Nerve-Gas Mimic
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TLDR
A o-phenylenediamine-pyronin linked dye that is capable of both fluorogenic and colorimetric discrimination between phosgene and the prototypical nerve-agent mimic, diethyl chlorophosphate (DCP) in the solution or gas phase is designed.Abstract:
The ability to analyze highly toxic chemical warfare agents (CWAs) and related chemicals in a rapid and precise manner is essential in order to alleviate serious threats to humankind and public security caused by unexpected terrorist attacks and industrial accidents. In this investigation, we designed a o-phenylenediamine-pyronin linked dye that is capable of both fluorogenic and colorimetric discrimination between phosgene and the prototypical nerve-agent mimic, diethyl chlorophosphate (DCP) in the solution or gas phase. Moreover, this dye has been used to construct a portable kit that can be employed for real-time monitoring of DCP and phosgene in the field, both in a discriminatory manner, and in a simple and safe way.read more
Citations
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Journal ArticleDOI
Functional Synthetic Probes for Selective Targeting and Multi-analyte Detection and Imaging
Yongkang Yue,Fangjun Huo,Fangqin Cheng,Xijing Zhu,Tendai Mafireyi,Robert M. Strongin,Caixia Yin +6 more
TL;DR: This review focuses on recent innovations in probe design, detection mechanisms and the investigation of biological processes and the ongoing development of fluorescent probes to enable deeper insight into the physiology of bioactive analytes.
Journal ArticleDOI
Recent Advances in the Development of Chromophore-Based Chemosensors for Nerve Agents and Phosgene
Liyan Chen,Di Wu,Juyoung Yoon +2 more
TL;DR: This review describes in a comprehensive manner recent progress that has been made on the development of chromophore-based chemosensors for detecting nerve agents (mimic) and phosgene.
Journal ArticleDOI
Recent progress in fluorescent probes for detection of carbonyl species: Formaldehyde, carbon monoxide and phosgene
TL;DR: In this paper, the most significant developments in fluorescent probes for the detection of the carbonyl species formaldehyde, carbon monoxide and phosgene in recent years, with a special emphasis on their mechanisms and applications.
Journal ArticleDOI
Effective Strategy for Colorimetric and Fluorescence Sensing of Phosgene Based on Small Organic Dyes and Nanofiber Platforms.
Ying Hu,Liyan Chen,Hyeseung Jung,Yiying Zeng,Songyi Lee,K.M.K. Swamy,Xin Zhou,Myung Hwa Kim,Juyoung Yoon +8 more
TL;DR: Three o-phenylendiamine derivatives, containing 4-chloro-7-nitrobenzo[c][1,2,5]oxadiazole, rhodamine, and 1,8-naphthalimide moieties, were prepared and tested as phosgene chemosensors and display distinct color and fluorescence changes upon exposure to phosGene even in the solid state.
Journal ArticleDOI
BODIPY-Based Fluorescent Sensor for the Recognization of Phosgene in Solutions and in Gas Phase
TL;DR: A highly selective fluorescent sensor o-Pab for phosgene with a BODIPY unit as a fluorophore and o-phenylenediamine as a reactive site is constructed and excellent discrimination of o- Pab has been demonstrated to be due to the difference in highly reactive and bifunctional phosGene relative to its substitutes.
References
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Journal ArticleDOI
A mitochondria-targetable fluorescent probe for peroxynitrite: fast response and high selectivity
Hong-Xing Zhang,Jing Liu,Yuan-Qiang Sun,Yingying Huo,Yaohua Li,Weizhi Liu,Xiao Wu,Nishu Zhu,Yawei Shi,Wei Guo +9 more
TL;DR: A mitochondria-targetable fluorescence probe, methyl(4-hydroxyphenyl)amino-substituted pyronin, was exploited, which could highly selectively sense peroxynitrite (ONOO(-)) within seconds.
Journal ArticleDOI
Fluorescent discrimination between traces of chemical warfare agents and their mimics.
Borja Díaz de Greñu,Daniel Moreno,Tomás Torroba,Alexander Berg,Johan Gunnars,Tobias Nilsson,Rasmus Nyman,Milton Persson,Johannes Pettersson,Ida Eklind,Pär Wästerby +10 more
TL;DR: An array of fluorogenic probes is able to discriminate between nerve agents, sarin, soman, tabun, VX and their mimics, in water or organic solvent, by qualitative fluorescence patterns and quantitative multivariate analysis, thus making the system suitable for the in-the-field detection of traces of chemical warfare agents.
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A selective turn-on fluorescent sensor for sulfur mustard simulants.
Vinod Kumar,Eric V. Anslyn +1 more
TL;DR: A fluorescent turn-on sensor for the selective and sensitive detection of sulfur mustard simulants in water that uses a metal-ion indicator displacement assay (IDA) has been devised and successfully used for the detection of the simulant present on surfaces and in soil samples.
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A Concise Colorimetric and Fluorimetric Probe for Sarin Related Threats Designed via the “Covalent-Assembly” Approach
Zuhai Lei,Youjun Yang +1 more
TL;DR: An embodiment of the "covalent-assembly" probe design principle is reported for detection of Sarin related threats, based on a phenylogous Vilsmeier-Haack reaction, which bears a concise molecular construct, exhibits a colorimetric and a fluorimetric signal, and has potential for real applications.
Journal ArticleDOI
A FRET-based ratiometric fluorescent and colorimetric probe for the facile detection of organophosphonate nerve agent mimic DCP
TL;DR: A FRET ratiometric fluorescent probe enabling a fast and highly sensitive response to OP nerve agent mimic DCP within 1 min and with as low as 0.17 ppm concentration detection limit has been developed.