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Open AccessJournal ArticleDOI

A task to assess behavioral pattern separation (BPS) in humans: Data from healthy aging and mild cognitive impairment.

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TLDR
The BPS-O task provides a sensitive measure for observing changes in memory performance across the lifespan and may be useful for the early detection of memory impairments that may provide an early signal of later development to mild cognitive impairment.
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This article is published in Neuropsychologia.The article was published on 2013-10-01 and is currently open access. It has received 408 citations till now. The article focuses on the topics: Recognition memory.

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Journal ArticleDOI

Network specialization during adolescence: Hippocampal effective connectivity in boys and girls.

TL;DR: A progressive reorganization among brain regions, with a commensurate increase in efficiency of cognitive functioning, from younger to older individuals in both girls and boys is suggested, providing insight into the age‐ and gender‐specific processes at play during this critical transition period.
Journal ArticleDOI

Retrieval of high-fidelity memory arises from distributed cortical networks.

TL;DR: In this article, the authors show that retrieval of detailed episodic memory arises from lateral cortical-MTL networks, including regions of inferior frontal and angular gyrii, and individual differences in microstructural properties in white matter pathways, associated with distributed MTL-cortical networks, are positively correlated with better performance on a mnemonic discrimination task.
Posted ContentDOI

Predicting age from cortical structure across the lifespan

TL;DR: The results reveal that age-related differences in brain structure are systematic enough to enable reliable age prediction based on metrics of cortical morphology, compared with a variety of structural measures, including thickness, gyrification, and fractal dimensionality.
Book ChapterDOI

Introduction to Memory

TL;DR: The role of these memory processes in the learning of new vocabulary and acquisition of the lexical rules subserving grammar, syntax, and morphology is discussed.
Journal ArticleDOI

Episodic memory contributions to autobiographical memory and open-ended problem-solving specificity in younger and older adults

TL;DR: The results show that age-related episodic memory decline impairs access to specific autobiographical events and detail information when remembering and problem solving, but that additional cognitive factors impact how these age declines present when solving problems.
References
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Journal ArticleDOI

Mild Cognitive Impairment: Clinical Characterization and Outcome

TL;DR: Patients who meet the criteria for MCI can be differentiated from healthy control subjects and those with very mild AD, and appear to constitute a clinical entity that can be characterized for treatment interventions.
Journal ArticleDOI

A new clinical scale for the staging of dementia.

TL;DR: The Clinical Dementia Rating (CRD) was developed for a prospective study of mild senile dementia—Alzheimer type (SDAT), and was found to distinguish unambiguously among older subjects with a wide range of cognitive function.
Journal ArticleDOI

Why there are complementary learning systems in the hippocampus and neocortex: insights from the successes and failures of connectionist models of learning and memory.

TL;DR: The account presented here suggests that memories are first stored via synaptic changes in the hippocampal system, that these changes support reinstatement of recent memories in the neocortex, that neocortical synapses change a little on each reinstatement, and that remote memory is based on accumulated neocorticals changes.
Journal ArticleDOI

Population-based norms for the mini-mental state examination by age and educational level

TL;DR: Results presented should prove to be useful to clinicians who wish to compare an individual patient's MMSE scores with a population reference group and to researchers making plans for new studies in which cognitive status is a variable of interest.
Journal ArticleDOI

Trail Making Test A and B: Normative data stratified by age and education

TL;DR: The current norms represent a more comprehensive set of norms than previously available and will increase the ability of neuropsychologists to determine more precisely the degree to which scores on the TMT reflect impaired performance for varying ages and education.
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