A task to assess behavioral pattern separation (BPS) in humans: Data from healthy aging and mild cognitive impairment.
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TLDR
The BPS-O task provides a sensitive measure for observing changes in memory performance across the lifespan and may be useful for the early detection of memory impairments that may provide an early signal of later development to mild cognitive impairment.About:
This article is published in Neuropsychologia.The article was published on 2013-10-01 and is currently open access. It has received 408 citations till now. The article focuses on the topics: Recognition memory.read more
Citations
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The Neural and Cognitive Basis of Cumulative Lifetime Familiarity Assessment
TL;DR: In this paper, a co-authorship statement and acknowledgements are given for co-authors and acknowledgments are given. Table of Table of contents of the co-Authorship Statement.
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The Contribution of Working Memory Areas to Verbal Learning and Recall in Primary Progressive Aphasia
Alexandros Afthinos,Charalambos Themistocleous,Olivia Herrmann,Hongli Fan,Hanzhang Lu,Kyrana Tsapkini +5 more
TL;DR: The authors found that the early stages of verbal learning involve the areas with subserving phonological processing (left superior temporal gyrus), as well as semantic WM memory (left angular gyrus, AG_L).
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The enhancing effect of 200 mg caffeine on mnemonic discrimination is at best small.
Frederik Aust,Christoph Stahl +1 more
TL;DR: Doubts are raised about a caffeine-mediated enhancement of mnemonic discrimination on two counts: if the effect exists, it is substantially smaller than originally reported and may reflect an offset of performance-impairing withdrawal symptoms rather than genuinely enhanced consolidation.
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Cardiorespiratory Fitness May Protect Memory for Poorer Sleepers
Tara Kuhn,Jennifer J. Heisz +1 more
TL;DR: Cardiorespiratory fitness may act as a protective buffer for memory in OA with poor sleep quality, suggesting that the protective effects of cardiorepiratory fitness on sleep-related memory impairments may be age specific.
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Is There a Role for Pattern Separation during Sleep
Jia-Hou Poh,James N. Cousins +1 more
TL;DR: Sleep plays an important role in supporting long-term memory formation and beyond preserving specific details from different events, sleep can facilitate the abstraction of generalities across events.
References
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Mild Cognitive Impairment: Clinical Characterization and Outcome
Ronald C. Petersen,Glenn E. Smith,Stephen C. Waring,Robert J. Ivnik,Eric G. Tangalos,Emre Kokmen +5 more
TL;DR: Patients who meet the criteria for MCI can be differentiated from healthy control subjects and those with very mild AD, and appear to constitute a clinical entity that can be characterized for treatment interventions.
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A new clinical scale for the staging of dementia.
TL;DR: The Clinical Dementia Rating (CRD) was developed for a prospective study of mild senile dementia—Alzheimer type (SDAT), and was found to distinguish unambiguously among older subjects with a wide range of cognitive function.
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Why there are complementary learning systems in the hippocampus and neocortex: insights from the successes and failures of connectionist models of learning and memory.
TL;DR: The account presented here suggests that memories are first stored via synaptic changes in the hippocampal system, that these changes support reinstatement of recent memories in the neocortex, that neocortical synapses change a little on each reinstatement, and that remote memory is based on accumulated neocorticals changes.
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Population-based norms for the mini-mental state examination by age and educational level
TL;DR: Results presented should prove to be useful to clinicians who wish to compare an individual patient's MMSE scores with a population reference group and to researchers making plans for new studies in which cognitive status is a variable of interest.
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Trail Making Test A and B: Normative data stratified by age and education
TL;DR: The current norms represent a more comprehensive set of norms than previously available and will increase the ability of neuropsychologists to determine more precisely the degree to which scores on the TMT reflect impaired performance for varying ages and education.