Journal ArticleDOI
α-Tricalcium phosphate: Synthesis, properties and biomedical applications
TLDR
It is as biocompatible as β-TCP, but more soluble, and hydrolyses rapidly to calcium-deficient hydroxyapatite, which makes α- TCP a useful component for preparing self-setting osteotransductive bone cements and biodegradable bioceramics and composites for bone repairing.About:
This article is published in Acta Biomaterialia.The article was published on 2011-10-01. It has received 479 citations till now.read more
Citations
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Journal ArticleDOI
Nanoscale hydroxyapatite particles for bone tissue engineering
Hongjian Zhou,Jaebeom Lee +1 more
TL;DR: This feature article looks afresh at nano-HAp particles, highlighting the importance of size, crystal morphology control, and composites with other inorganic particles for biomedical material development.
Journal ArticleDOI
Synthesis methods for nanosized hydroxyapatite with diverse structures.
TL;DR: This article is focused on nanosized HAp, although recent articles on microsized particles, especially those assembled from nanoparticles and/or nanocrystals, have been reviewed for comparison.
Journal ArticleDOI
Calcium phosphates in biomedical applications: materials for the future?
TL;DR: The aim of this manuscript is to highlight the tremendous improvements achieved in CaP materials research in the past 15 years, in particular in the field of biomineralization, as carrier for gene or ion delivery, as biologically active agent, and as bone graft substitute.
Journal ArticleDOI
Calcium phosphate ceramics in bone tissue engineering: a review of properties and their influence on cell behavior.
TL;DR: New insights on the contribution of material properties towards osteoinductivity and the role of signaling molecules involved in osteoblastic differentiation can potentially aid the design of CPC-based biomaterials that support bone regeneration without the need for additional biochemical supplements.
Journal ArticleDOI
Calcium phosphate cements for bone substitution: chemistry, handling and mechanical properties.
TL;DR: An overview on the chemistry, kinetics of setting and handling properties (setting time, cohesion and injectability) of CPCs for bone substitution, with a focus on their mechanical properties shows that, although the mechanical strength of CPC's is generally low, it is not a critical issue for their application for bone repair.
References
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Journal ArticleDOI
Formation of hydroxyapatite–polyphosphazene polymer composites at physiologic temperature
TL;DR: Conurrence of crosslinking of the polymer and HAp formation was established, indicating true composite formation can be realized at physiologic temperature.
Journal Article
A Water Setting Tetracalcium Phosphate- Dicalcium Phosphate Dihydrate Cement | NIST
TL;DR: Compared to previously reported TTCP-DCPD cements, the greater CS values and shorter setting times together with a simplified formulation should make the present TTCP/DCPD cement a useful material as a bone substitute for clinical applications.
Journal ArticleDOI
Effect of powder grinding on hydroxyapatite formation in a polymeric calcium phosphate cement prepared from tetracalcium phosphate and poly(methyl vinyl ether-maleic acid).
Yoko Matsuya,Shigeki Matsuya,Joseph M. Antonucci,Shozo Takagi,Laurence C. Chow,Akifumi Akamine +5 more
TL;DR: Hydxyapatite formation was detected in the cement prepared with the most finely ground tetracalcium phosphate powder, which will reduce the solubility of the polymeric cement and increase its biocompatibility.
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Histopathological study of a newly developed root canal sealer containing tetracalcium-dicalcium phosphates and 1.0% chondroitin sulfate.
TL;DR: Results indicate that TDM-S has excellent histocompatibility and potential as a root canal sealer and that ARS caused severe inflammatory reactions in both the subcutaneous and the periapical tissue.
Effects onWholeSaliva ofChewingGums Containing Calcium Phosphates
S. Takagi,A. Sieck +1 more
TL;DR: The results suggest that the experimental gums may be useful for promoting remineralization in general and for inducing salivation in xerostomic patients.