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Journal ArticleDOI

α-Tricalcium phosphate: Synthesis, properties and biomedical applications

Raúl García Carrodeguas, +1 more
- 01 Oct 2011 - 
- Vol. 7, Iss: 10, pp 3536-3546
TLDR
It is as biocompatible as β-TCP, but more soluble, and hydrolyses rapidly to calcium-deficient hydroxyapatite, which makes α- TCP a useful component for preparing self-setting osteotransductive bone cements and biodegradable bioceramics and composites for bone repairing.
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This article is published in Acta Biomaterialia.The article was published on 2011-10-01. It has received 479 citations till now.

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Citations
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Journal ArticleDOI

Nanoscale hydroxyapatite particles for bone tissue engineering

TL;DR: This feature article looks afresh at nano-HAp particles, highlighting the importance of size, crystal morphology control, and composites with other inorganic particles for biomedical material development.
Journal ArticleDOI

Synthesis methods for nanosized hydroxyapatite with diverse structures.

TL;DR: This article is focused on nanosized HAp, although recent articles on microsized particles, especially those assembled from nanoparticles and/or nanocrystals, have been reviewed for comparison.
Journal ArticleDOI

Calcium phosphates in biomedical applications: materials for the future?

TL;DR: The aim of this manuscript is to highlight the tremendous improvements achieved in CaP materials research in the past 15 years, in particular in the field of biomineralization, as carrier for gene or ion delivery, as biologically active agent, and as bone graft substitute.
Journal ArticleDOI

Calcium phosphate ceramics in bone tissue engineering: a review of properties and their influence on cell behavior.

TL;DR: New insights on the contribution of material properties towards osteoinductivity and the role of signaling molecules involved in osteoblastic differentiation can potentially aid the design of CPC-based biomaterials that support bone regeneration without the need for additional biochemical supplements.
Journal ArticleDOI

Calcium phosphate cements for bone substitution: chemistry, handling and mechanical properties.

TL;DR: An overview on the chemistry, kinetics of setting and handling properties (setting time, cohesion and injectability) of CPCs for bone substitution, with a focus on their mechanical properties shows that, although the mechanical strength of CPC's is generally low, it is not a critical issue for their application for bone repair.
References
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Journal ArticleDOI

Nuclear Magnetic Resonance Spectroscopy of Bone Substitutes

TL;DR: Comparatively high-resolution 31P solid-state nuclear magnetic resonance spectroscopy is able to analyze raw ceramics composition and to estimate osteoformation.
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In vitro interaction between tetracalcium phosphate-based cement and calvarial osteogenic cells.

TL;DR: In vitro findings suggest the ability of 4CP cement to bind directly with newly-formed hard tissues.
Journal ArticleDOI

Thermal Treatments of Calcium Phosphate Biomaterials to Tune the Physico-Chemical Properties and Modify the In Vitro Osteoclast Response

TL;DR: In this paper, a simple thermal treatment at temperatures of 450-600 °C was able to strongly modify the reactivity of α-tricalcium phosphate powders with water without significant change of physical properties.
Journal ArticleDOI

The Infrared and Raman Spectra of Tetracalcium Phosphate (Ca4P2O9)

TL;DR: In this paper, the infrared and Raman spectra of tetracalcium phosphate (Ca4P2O9) were measured and interpreted on the basis of factor group analysis.
Journal ArticleDOI

Infrared spectrum of strontium hydroxyapatite

TL;DR: In this paper, eine Methode berichtet, die es erlaubt, Apatide zu unterscheiden, in denen anstelle des Calciums Strontium eingetreten ist.
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