Journal ArticleDOI
α-Tricalcium phosphate: Synthesis, properties and biomedical applications
TLDR
It is as biocompatible as β-TCP, but more soluble, and hydrolyses rapidly to calcium-deficient hydroxyapatite, which makes α- TCP a useful component for preparing self-setting osteotransductive bone cements and biodegradable bioceramics and composites for bone repairing.About:
This article is published in Acta Biomaterialia.The article was published on 2011-10-01. It has received 479 citations till now.read more
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Journal ArticleDOI
Nanoscale hydroxyapatite particles for bone tissue engineering
Hongjian Zhou,Jaebeom Lee +1 more
TL;DR: This feature article looks afresh at nano-HAp particles, highlighting the importance of size, crystal morphology control, and composites with other inorganic particles for biomedical material development.
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Synthesis methods for nanosized hydroxyapatite with diverse structures.
TL;DR: This article is focused on nanosized HAp, although recent articles on microsized particles, especially those assembled from nanoparticles and/or nanocrystals, have been reviewed for comparison.
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Calcium phosphates in biomedical applications: materials for the future?
TL;DR: The aim of this manuscript is to highlight the tremendous improvements achieved in CaP materials research in the past 15 years, in particular in the field of biomineralization, as carrier for gene or ion delivery, as biologically active agent, and as bone graft substitute.
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Calcium phosphate ceramics in bone tissue engineering: a review of properties and their influence on cell behavior.
TL;DR: New insights on the contribution of material properties towards osteoinductivity and the role of signaling molecules involved in osteoblastic differentiation can potentially aid the design of CPC-based biomaterials that support bone regeneration without the need for additional biochemical supplements.
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Calcium phosphate cements for bone substitution: chemistry, handling and mechanical properties.
TL;DR: An overview on the chemistry, kinetics of setting and handling properties (setting time, cohesion and injectability) of CPCs for bone substitution, with a focus on their mechanical properties shows that, although the mechanical strength of CPC's is generally low, it is not a critical issue for their application for bone repair.
References
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Bioresorption behavior of tetracalcium phosphate-derived calcium phosphate cement implanted in femur of rabbits.
TL;DR: In this article, the crucial resorption-location relationship of a recently developed single-phase TTCP-derived calcium phosphate cement (CPC) implanted in rabbit femur was clarified in a systematic and quantitative way.
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Physicochemical study of plasma‐sprayed hydroxyapatite‐coated implants in humans
TL;DR: Findings indicate that there was some biointegration with the surrounding bone, but the greatest changes occurred with the HA coating materials, their loss, and chemical change.
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Ca4(PO4)2O, tetracalcium diphosphate monoxide. Crystal structure and relationships to Ca5(PO4)3OH and K3Na(SO4)2
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Crystalline Bioceramic Materials
TL;DR: A review of the composition, physiochemical properties and biological behaviour of the principal types of crystalline bioceramics is given, based on the literature data and on the own experience of the authors as discussed by the authors.