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Journal ArticleDOI

α-Tricalcium phosphate: Synthesis, properties and biomedical applications

Raúl García Carrodeguas, +1 more
- 01 Oct 2011 - 
- Vol. 7, Iss: 10, pp 3536-3546
TLDR
It is as biocompatible as β-TCP, but more soluble, and hydrolyses rapidly to calcium-deficient hydroxyapatite, which makes α- TCP a useful component for preparing self-setting osteotransductive bone cements and biodegradable bioceramics and composites for bone repairing.
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This article is published in Acta Biomaterialia.The article was published on 2011-10-01. It has received 479 citations till now.

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Citations
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Journal ArticleDOI

Nanoscale hydroxyapatite particles for bone tissue engineering

TL;DR: This feature article looks afresh at nano-HAp particles, highlighting the importance of size, crystal morphology control, and composites with other inorganic particles for biomedical material development.
Journal ArticleDOI

Synthesis methods for nanosized hydroxyapatite with diverse structures.

TL;DR: This article is focused on nanosized HAp, although recent articles on microsized particles, especially those assembled from nanoparticles and/or nanocrystals, have been reviewed for comparison.
Journal ArticleDOI

Calcium phosphates in biomedical applications: materials for the future?

TL;DR: The aim of this manuscript is to highlight the tremendous improvements achieved in CaP materials research in the past 15 years, in particular in the field of biomineralization, as carrier for gene or ion delivery, as biologically active agent, and as bone graft substitute.
Journal ArticleDOI

Calcium phosphate ceramics in bone tissue engineering: a review of properties and their influence on cell behavior.

TL;DR: New insights on the contribution of material properties towards osteoinductivity and the role of signaling molecules involved in osteoblastic differentiation can potentially aid the design of CPC-based biomaterials that support bone regeneration without the need for additional biochemical supplements.
Journal ArticleDOI

Calcium phosphate cements for bone substitution: chemistry, handling and mechanical properties.

TL;DR: An overview on the chemistry, kinetics of setting and handling properties (setting time, cohesion and injectability) of CPCs for bone substitution, with a focus on their mechanical properties shows that, although the mechanical strength of CPC's is generally low, it is not a critical issue for their application for bone repair.
References
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Journal ArticleDOI

Phase transformation of plasma-sprayed hydroxyapatite coating with preferred crystalline orientation.

TL;DR: These XRD results indicate that the tetracalcium phosphate in the as-prepared coatings transformed topotaxially into HA during the post-heat treatment.
Journal ArticleDOI

XANES analysis of calcium and sodium phosphates and silicates and hydroxyapatite–Bioglass®45S5 co-sintered bioceramics

TL;DR: In this paper, it was shown that the primary silicates present in these compositions are sodium silicates in the amorphous state, and that the silicates are in a similar structural environment in all the sintered bioceramic compositions with 4-fold coordination.
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Aqueous formation of hydroxyapatite

TL;DR: The kinetics of stoichiometric (Ca/P = 1.67) and calcium-deficient hydroxyapatite formed in aqueous solution by acid-base reactions involving CaHPO4 and Ca4(PO4)2O were determined and followed the Arrhenius relationship regardless of composition.
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Histologic evaluation of tetracalcium phosphate-based cement as a direct pulp-capping agent

TL;DR: It is suggested that 4CP cement possesses a biocompatible property, which indicates its potential for use as a direct pulp-capping agent.
Journal ArticleDOI

Thermal reconstruction behavior of the quenched hydroxyapatite powder during reheating in air

TL;DR: In this paper, commercial hydroxyapatite (HAP) powders were quenched from 1500°C to room temperature and reheated at different temperatures by a program controlled SiC-heated furnace to investigate the reconstruction behavior of Quenched HAP powder in air.
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