Journal ArticleDOI
α-Tricalcium phosphate: Synthesis, properties and biomedical applications
TLDR
It is as biocompatible as β-TCP, but more soluble, and hydrolyses rapidly to calcium-deficient hydroxyapatite, which makes α- TCP a useful component for preparing self-setting osteotransductive bone cements and biodegradable bioceramics and composites for bone repairing.About:
This article is published in Acta Biomaterialia.The article was published on 2011-10-01. It has received 479 citations till now.read more
Citations
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Journal ArticleDOI
Nanoscale hydroxyapatite particles for bone tissue engineering
Hongjian Zhou,Jaebeom Lee +1 more
TL;DR: This feature article looks afresh at nano-HAp particles, highlighting the importance of size, crystal morphology control, and composites with other inorganic particles for biomedical material development.
Journal ArticleDOI
Synthesis methods for nanosized hydroxyapatite with diverse structures.
TL;DR: This article is focused on nanosized HAp, although recent articles on microsized particles, especially those assembled from nanoparticles and/or nanocrystals, have been reviewed for comparison.
Journal ArticleDOI
Calcium phosphates in biomedical applications: materials for the future?
TL;DR: The aim of this manuscript is to highlight the tremendous improvements achieved in CaP materials research in the past 15 years, in particular in the field of biomineralization, as carrier for gene or ion delivery, as biologically active agent, and as bone graft substitute.
Journal ArticleDOI
Calcium phosphate ceramics in bone tissue engineering: a review of properties and their influence on cell behavior.
TL;DR: New insights on the contribution of material properties towards osteoinductivity and the role of signaling molecules involved in osteoblastic differentiation can potentially aid the design of CPC-based biomaterials that support bone regeneration without the need for additional biochemical supplements.
Journal ArticleDOI
Calcium phosphate cements for bone substitution: chemistry, handling and mechanical properties.
TL;DR: An overview on the chemistry, kinetics of setting and handling properties (setting time, cohesion and injectability) of CPCs for bone substitution, with a focus on their mechanical properties shows that, although the mechanical strength of CPC's is generally low, it is not a critical issue for their application for bone repair.
References
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Journal ArticleDOI
Ionic modification of calcium phosphate cement viscosity. Part II: hypodermic injection and strength improvement of brushite cement
TL;DR: It is demonstrated that an effective method for improving the injection properties of CPC was by the use of sodium citrate solution as a liquid component, resulting in high P:L mixes which were 400% stronger than cements made with water.
Journal ArticleDOI
Calcium phosphate bone cements for clinical applications. Part I: solution chemistry.
Enrique Fernández,Francisco Javier Gil,Maria-Pau Ginebra,F. C. M. Driessens,Josep A. Planell,Serena M. Best +5 more
TL;DR: Calcium phosphate cements have been the subject of many studies in the last decade because of their biocompatibility, their capacity to fill bone cavities and their hardening properties; properties which are desirable in a broad range of surgical applications.
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A calcium hydroxyapatite precipitated from an aqueous solution: An international multimethod analysis
J. Arends,Jørgen Christoffersen,Margaret R. Christoffersen,Hellmut Eckert,B.O. Fowler,J.C. Heughebaert,George H. Nancollas,James P. Yesinowski,S.J. Zawacki +8 more
TL;DR: In this paper, a pure calcium hydroxyapatite prepared from aqueous solutions at low temperature, was analysed by a large number of techniques in six Institutes, including X-ray diffraction, IR analysis, BET measurement, chemical analysis, differential thermal analysis, magic angle spinning NMR, TEM, size distribution measurements, crystal growth and crystal dissolution measurements.
Journal ArticleDOI
Development of a new calcium phosphate powder-binder system for the 3D printing of patient specific implants
Alaadien Khalyfa,Sebastian Vogt,Jürgen Weisser,Gabriele Grimm,Annett Rechtenbach,Wolfgang Dr. Meyer,Matthias Schnabelrauch +6 more
TL;DR: Preliminary examinations on relevant application properties including in vitro cytocompatibility testing indicate that the new powder-binder system represents an efficient approach to patient specific ceramic bone substitutes and scaffolds for bone tissue engineering.
Journal ArticleDOI
Degradation characteristics of α and β tri-calcium-phosphate (TCP) in minipigs
J. Wiltfang,H. A. Merten,K. A. Schlegel,S. Schultze-Mosgau,F. R. Kloss,Rupprecht S,Peter Kessler +6 more
TL;DR: According to the results of this animal experiment both alpha- and beta-TCP materials can be classified as bone-rebuilding materials.