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Journal ArticleDOI

α-Tricalcium phosphate: Synthesis, properties and biomedical applications

Raúl García Carrodeguas, +1 more
- 01 Oct 2011 - 
- Vol. 7, Iss: 10, pp 3536-3546
TLDR
It is as biocompatible as β-TCP, but more soluble, and hydrolyses rapidly to calcium-deficient hydroxyapatite, which makes α- TCP a useful component for preparing self-setting osteotransductive bone cements and biodegradable bioceramics and composites for bone repairing.
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This article is published in Acta Biomaterialia.The article was published on 2011-10-01. It has received 479 citations till now.

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Journal ArticleDOI

Nanoscale hydroxyapatite particles for bone tissue engineering

TL;DR: This feature article looks afresh at nano-HAp particles, highlighting the importance of size, crystal morphology control, and composites with other inorganic particles for biomedical material development.
Journal ArticleDOI

Synthesis methods for nanosized hydroxyapatite with diverse structures.

TL;DR: This article is focused on nanosized HAp, although recent articles on microsized particles, especially those assembled from nanoparticles and/or nanocrystals, have been reviewed for comparison.
Journal ArticleDOI

Calcium phosphates in biomedical applications: materials for the future?

TL;DR: The aim of this manuscript is to highlight the tremendous improvements achieved in CaP materials research in the past 15 years, in particular in the field of biomineralization, as carrier for gene or ion delivery, as biologically active agent, and as bone graft substitute.
Journal ArticleDOI

Calcium phosphate ceramics in bone tissue engineering: a review of properties and their influence on cell behavior.

TL;DR: New insights on the contribution of material properties towards osteoinductivity and the role of signaling molecules involved in osteoblastic differentiation can potentially aid the design of CPC-based biomaterials that support bone regeneration without the need for additional biochemical supplements.
Journal ArticleDOI

Calcium phosphate cements for bone substitution: chemistry, handling and mechanical properties.

TL;DR: An overview on the chemistry, kinetics of setting and handling properties (setting time, cohesion and injectability) of CPCs for bone substitution, with a focus on their mechanical properties shows that, although the mechanical strength of CPC's is generally low, it is not a critical issue for their application for bone repair.
References
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Journal ArticleDOI

Untersuchungen im System CaOP2O5SiO2

TL;DR: The Gleichgewichte im kalkreiche Teil des Systems CaOP2O5SiO2 wurden thermisch, rontgenographisch und mikroskopisch untersucht as discussed by the authors.
Journal ArticleDOI

Basic properties of apatite cement containing spherical tetracalcium phosphate made with plasma melting method.

TL;DR: In this article, spherical tetracalcium phosphate (s-TTCP) was prepared with plasma melting method and its effect on injectability were evaluated as well as other basic properties of AC.
Journal ArticleDOI

The effect of crystallinity on strength development of alpha-TCP bone substitutes.

TL;DR: It is proposed that increasing reactivity of alpha-TCP cements does not result in a corresponding increase in rate of strength development until there is sufficient supersaturation to produce significant crystal nucleation.
Journal ArticleDOI

Preparation and In Vitro Characterization of Wollastonite Doped Tricalcium Phosphate Bioceramics

TL;DR: In this article, a new kind of CaSiO3-doped α-Ca3(PO4)2 ceramic materials, with compositions lying outside the field of the Ca3PO42 solid solution, were obtained and some of their properties, relevant for bone repairing, were studied in vitro.
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