Acute kidney injury in ECMO patients.
Reads0
Chats0
TLDR
In this article, an update of the epidemiology, outcomes and pathophysiology of acute kidney injury in patients receiving ECMO, highlights technical aspects when combining Renal Replacement Therapy (RRT) with ECMO and identifies future research questions.Abstract:
Acute kidney injury is a common complication in patients receiving extracorporeal membrane oxygenation (ECMO). The underlying mechanisms are multifactorial including the primary disease, effects of invasive mechanical ventilation, ECMO circuit-related factors and critical illness in general. Renal replacement therapy (RRT) is often required to control fluid balance and is associated with worse outcomes. No consensus exists for indication, timing, modality, and how to best to combine RRT and ECMO. This chapter provides an update of the epidemiology, outcomes and pathophysiology of acute kidney injury in patients receiving ECMO, highlights technical aspects when combining RRT with ECMO, and identifies future research questions.read more
Citations
More filters
Journal ArticleDOI
Higher rates of Dialysis and Subsequent Mortality in the New Allocation Era for Heart Transplants.
Max Shin,Jason J. Han,William Cohen,Amit Iyengar,Mark R. Helmers,John D. Kelly,William L. Patrick,Xingmei Wang,Marisa Cevasco +8 more
TL;DR: In this paper , a United Network for Organ Sharing (UNOS) policy change increased prioritization of patients bridged with temporary mechanical circulatory support devices, such as venoarterial ECMO, for cardiac transplantation.
Journal ArticleDOI
Early Levosimendan Administration Improved Weaning Success Rate in Extracorporeal Membrane Oxygenation in Patients With Cardiogenic Shock
Yu Wen Chen,Wei-Chieh Lee,Po-Jui Wu,Hsiu-Yu Fang,Yen-Nan Fang,Huang-Chung Chen,Meng-Shen Tong,Pei-Hsun Sung,Chieh-Ho Lee,Wen-Hung Chung +9 more
TL;DR: Early levosimendan administration may contribute to increasing the success rate of VA-ECMO weaning and may help to decrease CV and all-cause mortality.
Journal ArticleDOI
Complications Associated With Venovenous Extracorporeal Membrane Oxygenation—What Can Go Wrong?
TL;DR: In this paper , a narrative review describes the variety of short and long-term complications that can occur during treatment with ECMO and how patient selection and management decisions may influence the risk of these complications.
Journal ArticleDOI
Does delivering more dialysis improve clinical outcomes? What randomized controlled trials have shown
TL;DR: In this article , the authors present a narrative review of randomized controlled trials (RCTs) on end-stage kidney disease (ESKD) patients with different dialysis techniques, dialysis doses and frequencies of treatment.
Journal ArticleDOI
Veno-Arterial Extracorporeal Membrane Oxygenation in Elective High-Risk Percutaneous Coronary Interventions
TL;DR: Velo-arterial extracorporeal membrane oxygenation mechanical circulation support during HR-PCI is a safe and feasible strategy for achieving revascularisation in complex and high-risk coronary artery lesions.
References
More filters
Journal ArticleDOI
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.
Roy G. Brower,Michael A. Matthay,Alan H. Morris,David A. Schoenfeld,B. Taylor Thompson,Arthur P. Wheeler +5 more
TL;DR: In patients with acute lung injury and the acute respiratory distress syndrome, mechanical ventilation with a lower tidal volume than is traditionally used results in decreased mortality and increases the number of days without ventilator use.
Journal ArticleDOI
Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit
Stéphane Gaudry,David Hajage,Frédérique Schortgen,Laurent Martin-Lefevre,Bertrand Pons,Eric Boulet,Alexandre Boyer,Guillaume Chevrel,Nicolas Lerolle,Dorothée Carpentier,Nicolas de Prost,Alexandre Lautrette,Anne Bretagnol,Julien Mayaux,Saad Nseir,Bruno Mégarbane,Marina Thirion,Jean-Marie Forel,Julien Maizel,Hodane Yonis,Philippe Markowicz,Guillaume Thiery,Florence Tubach,Jean-Damien Ricard,Didier Dreyfuss +24 more
TL;DR: In a trial involving critically ill patients with severe acute kidney injury, a delayed strategy averted the need for renal-replacement therapy in an appreciable number of patients and found no significant difference with regard to mortality.
Journal ArticleDOI
Decline in Estimated Glomerular Filtration Rate and Subsequent Risk of End-Stage Renal Disease and Mortality
Josef Coresh,Tanvir Chowdhury Turin,Kunihiro Matsushita,Yingying Sang,Shoshana H. Ballew,Lawrence J. Appel,Hisatomi Arima,Steven J. Chadban,Steven J. Chadban,Massimo Cirillo,Ognjenka Djurdjev,Jamie A. Green,Gunnar H. Heine,Lesley A. Inker,Fujiko Irie,Areef Ishani,Joachim H. Ix,Csaba P. Kovesdy,Csaba P. Kovesdy,Angharad Marks,Takayoshi Ohkubo,Takayoshi Ohkubo,Takayoshi Ohkubo,Varda Shalev,Anoop Shankar,Chi Pang Wen,Chi Pang Wen,Paul E. de Jong,Kunitoshi Iseki,Bénédicte Stengel,Ron T. Gansevoort,Andrew S. Levey +31 more
TL;DR: Declines in estimated GFR smaller than a doubling of serum creatinine concentration occurred more commonly and were strongly and consistently associated with the risk of ESRD and mortality, supporting consideration of lesser declines in Estimated GFR (such as a 30% reduction over 2 years) as an alternative end point for CKD progression.
Journal ArticleDOI
Extracorporeal Life Support Organization Registry International Report 2016.
Ravi R. Thiagarajan,Ryan P. Barbaro,Peter Rycus,D. Michael McMullan,Steven A. Conrad,James D. Fortenberry,Matthew L. Paden +6 more
TL;DR: Extracorporeal life support use in the support of adults with respiratory and cardiac failure represented the largest growth in the recent time period and underscore the need for skilled ECLS management and appropriately trained ECLs personnel and teams.
Journal ArticleDOI
Timing of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis.
Saber Barbar,Raphaël Clere-Jehl,Abderrahmane Bourredjem,Romain Hernu,Florent Montini,Rémi Bruyère,Christine Lebert,Julien Bohé,Julio Badie,Jean-Pierre Eraldi,Jean-Philippe Rigaud,Bruno Levy,Shidasp Siami,Guillaume Louis,Lila Bouadma,Jean-Michel Constantin,Emmanuelle Mercier,Kada Klouche,Damien du Cheyron,Gaël Piton,Djillali Annane,Samir Jaber,Thierry Van Der Linden,Gilles Blasco,Jean-Paul Mira,Carole Schwebel,Loïc Chimot,Philippe Guiot,Mai-Anh Nay,Ferhat Meziani,Julie Helms,Claire Roger,Benjamin Louart,Remi Trusson,Auguste Dargent,Christine Binquet,Jean-Pierre Quenot +36 more
TL;DR: Among patients with septic shock who had severe acute kidney injury, there was no significant difference in overall mortality at 90 days between patients who were assigned to an early strategy for the initiation of renal‐replacement therapy and those who were assign to a delayed strategy.