Journal ArticleDOI
Adrenal involvement in captopril-induced potentiation of morphine analgesia
TLDR
Althoughcaptopril could inhibit the plasma angiotensin-converting enzyme activity, it appeared to have no significant effect on the brain enzyme, and it has been suggested that the effects of captopril and angiotENSin II on morphine analgesia are mediated indirectly through their effects on adrenal function.About:
This article is published in European Journal of Pharmacology.The article was published on 1982-11-19. It has received 11 citations till now. The article focuses on the topics: Captopril & Angiotensin II.read more
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Distribution and properties of angiotensin converting enzyme of rat brain
H.‐Y. T. Yang,Norton H. Neff +1 more
TL;DR: The broad substrate specificity of the enzymes suggests that, in addition to the possible contribution of the enzyme to the brain renin‐angiotensin system, other naturally occurring peptides might also be substrates for the enzyme.
Journal ArticleDOI
Two distinct enkephalinases: solubilization, partial purification and separation from angiotensin converting enzyme.
TL;DR: Enkephalinase A activity can be completely resolved by DEAE column chromatography from angiotensin converting enzyme activity, demonstrating that they are distinct enzymes.
Journal ArticleDOI
Selective protection of methionine enkephalin released from brain slices by enkephalinase inhibition.
Gilles Patey,S. de la Baume,J.-C. Schwartz,C. Gros,Bernard P. Roques,M.-C. Fournie-Zaluski,E Soroca-Lucas +6 more
TL;DR: The data indicate that enkephalinase is critically involved in the inactivation of the endogenous opioid peptide released from striatal neurons.
Journal ArticleDOI
Co-identity of brain angiotensin converting enzyme with a membrane bound dipeptidyl carboxypeptidase inactivating Met - enkephalin.
Myron Benuck,Neville Marks +1 more
TL;DR: The distribution in rat brain of angiotensin converting enzyme using hippuryl-His-Leu as substrate was identical to a dipeptidyl carboxypeptidase present in membranes assayed with Met-enkephalin as substrate.
Related Papers (5)
Involvement of the renin-angiotensin system in the dipsogenic effect of morphine.
Lal J,Atkinson J +1 more