Journal ArticleDOI
Alpha-1-antitrypsin, autism, and cœliac disease
Reads0
Chats0
About:
This article is published in The Lancet.The article was published on 1972-10-21. It has received 553 citations till now. The article focuses on the topics: Alpha (ethology) & Autism.read more
Citations
More filters
Journal ArticleDOI
The CGRP receptor antagonist BIBN4096 inhibits prolonged meningeal afferent activation evoked by brief local K+ stimulation but not cortical spreading depression-induced afferent sensitization.
TL;DR: While C GRP-mediated activation of meningeal afferents evoked by cortical efflux of K+ could promote headache, acute activation of CGRP receptors may not play a key role in mediating CSD-evoked headache.
Journal ArticleDOI
Measurement of antibodies to pneumococcal, meningococcal and haemophilus polysaccharides, and tetanus and diphtheria toxoids using a 19-plexed assay.
Alison Whitelegg,Jane Birtwistle,Alex G. Richter,John Campbell,James E. Turner,Tarana M. Ahmed,Lynda J. Giles,Mark Fellows,Tim Plant,Alastair J. Ferraro,Alastair J. Ferraro,Mark Cobbold,Mark T. Drayson,Calman A. MacLennan,Calman A. MacLennan +14 more
TL;DR: A flow cytometric bead-based assay is optimized to measure IgG and IgM concentrations in serum to 19 antigens contained in groups of bacterial subunit vaccines: pneumococcal vaccines, meningococcal vaccine, Haemophilus influenzae b (Hib), and tetanus and diphtheria toxoid vaccines.
Journal ArticleDOI
Beta-blocker use in ST-segment elevation myocardial infarction in the reperfusion era (GRACE)
Kay Lee Park,Robert J. Goldberg,Frederick A. Anderson,Jose Lopez-Sendon,Gilles Montalescot,David Brieger,Kim A. Eagle,Allison Wyman,Joel M. Gore +8 more
TL;DR: Early beta-blocker use is common in patients presenting with ST-elevation myocardial infarction, with oral administration being the most prevalent, and the early receipt of any form of Beta-blockers was associated with an increase in hospital mortality.
Journal ArticleDOI
Kupffer cell–depleted rats have a diminished acute-phase response following major liver resection
Hubert A. Prins,C. Meijer,Petra G. Boelens,J. Diks,Rogier Holtz,Sylvie Masson,Maryvonne Daveau,Sybren L. Meijer,Michel Scotté,Paul A. M. van Leeuwen +9 more
TL;DR: It is concluded that after PH, KC function in the remnant liver is important for the acute-phase reaction and reduces endotoxin-induced hepatocyte damage.
References
More filters
Journal Article
Manifestations of Immunologic Unresponsiveness in Hodgkin's Disease
TL;DR: It is suggested that the anergy of early Hodgkin's disease is a peripheral defect; a manifestation of abnormal lymphocyte function; this suggestion is supported by preliminary work with Hodgkins lymphocytes in vitro and following lymphocyte transfer.
Journal ArticleDOI
Zinc deficiency: effect on brain of the suckling rat.
TL;DR: Zinc deficiency has been showed to impair DNA and protein synthesis in brain of the suckling rat as it has previously been shown to do in other tissues including liver and epiphyseal plate.
Journal ArticleDOI
Symptomatic pulmonary emphysema in childhood associated with hereditary alpha-1-antitrypsin and elastase inhibitor deficiency.
Richard C. Talamo,Henry Levison,Matthew J. Lynch,Albert Hercz,Newton E. Hyslop,Harry W. Bain +5 more
TL;DR: Genetic studies of sera from 55 family members were performed by means of functional assays of elastase inhibition and total antitryptic activity and by measurements of alpha-1-antitrypsin concentration with a newly developed sensitive electroimmunodiffusion method.