Journal ArticleDOI
An ESIPT-based fluorescent probe for highly selective and ratiometric detection of mercury(II) in solution and in cells.
Biao Gu,Liyan Huang,Naxiu Mi,Peng Yin,Youyu Zhang,Xinman Tu,Xubiao Luo,Shenlian Luo,Shouzhuo Yao +8 more
Reads0
Chats0
TLDR
Results indicated that the probe and the proposed method have promising applications for Hg(2+) sensing in biological and environmental sciences.Abstract:
A novel ratiometric fluorescent Hg(2+) detecting system was rationally developed based on the typical excited state intramolecular proton transfer (ESIPT) characteristic of the latent fluorophore, 2-(1-(p-tolyl)-1H-phenanthro[9,10-d]imidazol-2-yl)phenol (Pol) and the Hg(2+)-mediated cleavage of the vinyl group. The probe responds selectively to Hg(2+) over various other metal ions with a larger bathochromic shift (∼100 nm). The sensing mechanism was investigated in detail by fluorescence spectroscopy, NMR spectra and mass spectrometry. Taking advantage of the enhancement effect of dichloromethane on the ESIPT efficiency, a facile dichloromethane extraction was introduced in the process of detection of Hg(2+), which affords a high sensitivity for the probe with a detection limit of 7.8 × 10(-9) M for Hg(2+). By using the new strategy, the novel probe can be used for the detection of Hg(2+) in practical water samples with good recovery. Moreover, the probe was successfully applied to the fluorescence image of Hg(2+) in living cells. These results indicated that the probe and the proposed method have promising applications for Hg(2+) sensing in biological and environmental sciences.read more
Citations
More filters
Journal ArticleDOI
Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents
Adam C. Sedgwick,Luling Wu,Hai Hao Han,Steven D. Bull,Xiao-Peng He,Tony D. James,Tony D. James,Jonathan L. Sessler,Ben Zhong Tang,He Tian,Juyoung Yoon +10 more
TL;DR: This review will explore recent advances in the design and application of excited-state intramolecular proton-transfer (ESIPT) based fluorescent probes.
Journal ArticleDOI
Synthetic ratiometric fluorescent probes for detection of ions
TL;DR: In this review, recent advances made in the development and biological applications of synthetic ratiometric fluorescent probes are described and particular emphasis is given to organic dye-based ratiomet fluorescent probes that are designed to detect biologically important and relevant ions in cells and living organisms.
Journal ArticleDOI
A Highly Sensitive ESIPT-Based Ratiometric Fluorescence Sensor for Selective Detection of Al3+
TL;DR: Density functional theoretical (DFT) calculations provide the ground- and excited-state energy optimized structures and properties of the proposed aluminum complex [Al(1) (OH)]2(2+), which is in harmony with the solution-state experimental findings and also supports the occurrence of ESIPT process in 1H.
Journal ArticleDOI
A ratiometric fluorescent probe for formaldehyde in aqueous solution, serum and air using aza-cope reaction
TL;DR: In this paper, a ratiometric fluorescent probe (HBT-FA) based on aza-Cope reaction was designed and synthesized, which showed high selectivity and ratiometric fluorescence response to FA.
Journal ArticleDOI
A two-photon fluorescent probe for colorimetric and ratiometric monitoring of mercury in live cells and tissues.
TL;DR: A naphthalimide-based diphenylphosphinothioyl group-containing fluorescent and colorimetric probe that selectively detects mercury (Hg2+) and possesses the capability of sensing intracellular mercury in both live cells and tissues using dual-emission channels and two-photon microscopy.
References
More filters
Journal ArticleDOI
New sensing mechanisms for design of fluorescent chemosensors emerging in recent years
TL;DR: New fluorescent sensing mechanisms that have emerged in the past five years, such as aggregation-induced emission (AIE) and C=N isomerization, which can be ascribed to fluorescence changes via conformational restriction are focused on.
Journal ArticleDOI
A Ratiometric Fluorescent Probe Based on FRET for Imaging Hg2+ Ions in Living Cells
Journal ArticleDOI
A "turn-on" fluorescent sensor for the selective detection of mercuric ion in aqueous media.
TL;DR: The synthesis and metal-binding properties of MS1 are discussed, and its ability to detect environmentally relevant concentrations of Hg(II) is demonstrated.
Journal ArticleDOI
A Rapid Aqueous Fluoride Ion Sensor with Dual Output Modes
TL;DR: A rapid and portable sensor for fluoride ions in aqueous solution, which has a high sensitivity, operates through the special affinity between fluoride ions and silicon, and provides two independent modes of signal transduction based on fluoride-dependent changes of fluorescence color or intensity, respectively.
Journal ArticleDOI
Turn-On and Ratiometric Mercury Sensing in Water with a Red-Emitting Probe
TL;DR: Studies of natural water samples spiked with mercuric salts indicate that MS5 can rapidly detect Hg(II) in such complex solutions and demonstrate its potential utility in the field.