Journal ArticleDOI
An optimized pulse sequence for isotropically weighted diffusion imaging.
M. Cercignani,Mark A. Horsfield +1 more
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TLDR
An isotropically weighted echo-planar pulse sequence, optimized to give the maximum signal-to-noise ratio in the computed trace image and designed to produce inherently low distortions, is presented and how the residual translational distortion can be easily characterized and removed by postprocessing is shown.About:
This article is published in Journal of Magnetic Resonance.The article was published on 1999-09-01. It has received 17 citations till now. The article focuses on the topics: Distortion & Imaging phantom.read more
Citations
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Journal ArticleDOI
A quantitative study of water diffusion in multiple sclerosis lesions and normal-appearing white matter using echo-planar imaging.
TL;DR: This study shows that diffusion-weighted imaging is able to identify MS lesions with severe tissue disruption and shows that widespread increased diffusion can be measured in the NAWM from patients with MS, and suggests that such changes are, at least partially, independent of larger abnormalities.
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Pathologic damage in MS assessed by diffusion-weighted and magnetization transfer MRI.
TL;DR: DWI detects severe tissue disruption inside lesions and subtle widespread abnormalities in NAWM in patients with relapsing-remitting MS and MT and DWI may provide information about different aspects of brain pathology in MS.
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Weekly diffusion-weighted imaging of normal-appearing white matter in MS.
TL;DR: It is suggested that focal edema and demyelination play a part in the NAWM changes preceding new lesion formation in MS. the authors obtained weekly diffusion-weighted images for 12 weeks from 6 patients.
Journal ArticleDOI
On the use of water phantom images to calibrate and correct eddy current induced artefacts in MR diffusion tensor imaging
Mark E. Bastin,Paul A. Armitage +1 more
TL;DR: The practicalities of using separate phantom calibration data to correct high b-value diffusion tensor imaging data are examined by investigating the stability of these distortion parameters, and hence the eddy currents, with time, and it is found that M, T, and S vary only slowly with time.
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Structural and metabolic changes in the brain of patients with upper motor neuron disorders: a multiparametric MRI study.
Arnaud Charil,Massimo Corbo,Massimo Filippi,Chandrasekharan Kesavadas,Federica Agosta,Elisabetta Munerati,A. Gambini,Giancarlo Comi,Giuseppe Scotti,Andrea Falini +9 more
TL;DR: The study shows the utility of cMRI for diagnosing ALS, and MRI sensitivity is limited at the early stages of the disease, and DWI and 1H-MRSI seem to have the potential to ameliorate the patients’ work-up and estimate the nature and extent of the underlying pathological damage.
References
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Journal ArticleDOI
MR diffusion tensor spectroscopy and imaging.
TL;DR: Once Deff is estimated from a series of NMR pulsed-gradient, spin-echo experiments, a tissue's three orthotropic axes can be determined and the effective diffusivities along these orthotropic directions are the eigenvalues of Deff.
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Fast magnetic resonance diffusion‐weighted imaging of acute human stroke
TL;DR: Rapid MRI of the molecular diffusion of water demonstrated cerebral infarcts in 32 patients at various times following the onset of ischemic symptoms and found that diffusion-weighted imaging revealed the infarCTs sooner than conventional T2- weighted spin-echo imaging did.
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Automated three-dimensional registration of magnetic resonance and positron emission tomography brain images by multiresolution optimization of voxel similarity measures
TL;DR: A method of multiresolution optimization of five measures of voxel intensity similarity is described and the mutual information measure proved the most robust to initial starting estimate, successfully registering 98.8% of 900 trial misregistrations.
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Echo-planar imaging of intravoxel incoherent motion.
TL;DR: The phantom results demonstrate that perfusion levels comparable with those found in vivo have easily observable and reproducible effects on signal amplitude that are consistent with previous IVIM theory.
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Clinical outcome in ischemic stroke predicted by early diffusion-weighted and perfusion magnetic resonance imaging: a preliminary analysis
TL;DR: Preliminary evidence is provided from an analysis of 19 patients with severely disabling clinical deficits attributable to ischemia in at least an entire division of the middle cerebral artery that initial perfusion and diffusion MRI were more accurate than conventional MRI in predicting no, partial or complete improvement.