Journal ArticleDOI
Anteroposterior gradients in cerebral glucose use in schizophrenia and affective disorders.
Monte S. Buchsbaum,Lynn E. DeLisi,Henry H. Holcomb,J. Cappelletti,A C King,Jeannette L. Johnson,Erin A. Hazlett,Susan Dowling-Zimmerman,Robert M. Post,John M. Morihisa,William T. Carpenter,Robert M. Cohen,David Pickar,Daniel R. Weinberger,Richard Margolin,R. M. Kessler +15 more
Reads0
Chats0
TLDR
Local cerebral uptake of deoxyglucose labeled with fluorine 18 was measured by positron emission tomography in patients with schizophrenia and patients with affective disorder, sharing a lack of diagnostic specificity with many biologic measures.Citations
More filters
Journal ArticleDOI
Morphometric methods for studying the prefrontal cortex in suicide victims and psychiatric patients.
TL;DR: It is concluded that the morphopathology observed in brain tissue from suicide victims appears to vary based on psychiatric symptomatology, and additional studies are warranted in nonsuicide subjects with SCZ, major depression, or bipolar disorder.
Journal ArticleDOI
Nonlinear analysis of the EEG of schizophrenics with optimal embedding dimension.
TL;DR: The finding of decreased left frontal and temporal chaotic activity in schizophrenics is in line with the findings of a hypofrontality and hypotemporality reported in previous clinical studies such as EEG, blood flow, brain MRI and positron emission tomography studies in schizophrenia.
Journal ArticleDOI
Regional cerebral glucose metabolism and attention in adults with a history of childhood autism.
Benjamin V. Siegel,Robert F. Asarnow,Peter E. Tanguay,Justin D. Call,Lennart Abel,Andrew P. Ho,Ira T. Lott,Monte S. Buchsbaum +7 more
TL;DR: High-functioning adults with a history of childhood autism and normal control subjects underwent [18F]fluoro-2-deoxyglucose positron-emission tomography to assess regional cerebral glucose metabolic rate (GMR), finding autistic patients had a left > right anterior rectal gyrus asymmetry.
Journal ArticleDOI
Relationship between depression and borderline personality disorder.
Harold W. Koenigsberg,Iseoma Anwunah,Antonia S. New,Vivian Mitropoulou,Frances Schopick,Larry J. Siever +5 more
TL;DR: The less parsimonious hypothesis that the disorders co‐occur is proposed, both because they share some common biological features and because the psychosocial sequella of each can contribute to the development of the other.
Journal ArticleDOI
Regional brain function in hallucinations: A study of regional cerebral blood flow with 99m-Tc-HMPAO-SPECT in patients with auditory hallucinations, tactile hallucinations, and normal controls
TL;DR: The results support Jackson's hypothesis to the effect that hallucinatory phenomena will primarily occur when the normally inhibitive influence of the upper cortical centers over the lower brain structures diminishes, resulting in relative hyperactivity in the basal regions.
References
More filters
Manual for the State-Trait Anxiety Inventory
TL;DR: The STAI as mentioned in this paper is an indicator of two types of anxiety, the state and trait anxiety, and measure the severity of the overall anxiety level, which is appropriate for those who have at least a sixth grade reading level.
Journal ArticleDOI
The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat.
Louis Sokoloff,Martin Reivich,Charles Kennedy,Charles Kennedy,M. H. Des Rosiers,Clifford S. Patlak,Karen D. Pettigrew,O. Sakurada,M. Shinohara +8 more
TL;DR: The method can be applied to most laboratory animals in the conscious state and is based on the use of 2‐deoxy‐D‐[14C]glucose as a tracer for the exchange of glucose between plasma and brain and its phosphorylation by hexokinase in the tissues.
Journal ArticleDOI
A Diagnostic Interview: The Schedule for Affective Disorders and Schizophrenia
Jean Endicott,Robert L. Spitzer +1 more
TL;DR: Initial scale development and reliability studies of the items and the scale scores are reported on.
Journal ArticleDOI
Tomographic measurement of local cerebral glucose metabolic rate in humans with (F-18)2-fluoro-2-deoxy-D-glucose: validation of method.
Michael E. Phelps,Michael E. Phelps,Sung-Cheng Huang,Sung-Cheng Huang,Edward J. Hoffman,Edward J. Hoffman,Carl Selin,Carl Selin,L. Sokoloff,L. Sokoloff,David E. Kuhl,David E. Kuhl +11 more
TL;DR: The data indicate that cerebral FDG‐6‐PO4 in humans increases for about 90 minutes, plateaus, and then slowly decreases, and that cerebral blood FDG activity levels were found to be a minor fraction of tissue activity.
Related Papers (5)
Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence.
Abnormalities of cerebral blood flow distribution in patients with chronic schizophrenia
David H. Ingvar,G. Franzén +1 more