Journal ArticleDOI
Anticancer potential of andrographolide from Andrographis paniculata (Burm.f.) Nees and its mechanisms of action.
Zoya Malik,Rabea Parveen,Bushra Parveen,Sultan Zahiruddin,Mohammad Aasif Khan,Asifa Khan,Sheersh Massey,Sayeed Ahmad,Syed Akhtar Husain +8 more
TLDR
In this article, the main emphasis was given on the anticancer activity of AG, its proposed mechanisms of action, novel approaches used to improve its biopharmaceutical properties, and its development as an adjuvant therapy for cancer treatment in future.About:
This article is published in Journal of Ethnopharmacology.The article was published on 2021-02-18. It has received 26 citations till now. The article focuses on the topics: Andrographis paniculata & Literature survey.read more
Citations
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Journal ArticleDOI
Recent Developments in Inonotus obliquus (Chaga mushroom) Polysaccharides: Isolation, Structural Characteristics, Biological Activities and Application
TL;DR: Inonotus obliquus (Chaga mushroom) is a kind of medicine and health food widely used by folk in China, Russia, Korea, and some occidental countries as discussed by the authors.
Journal ArticleDOI
Andrographolide: A review of its pharmacology, pharmacokinetics, toxicity and clinical trials and pharmaceutical researches.
TL;DR: Wang et al. as discussed by the authors presented a comprehensive review of andrographis paniculata (Burm. f. ex Nees), including its pharmacology, pharmacokinetics, toxicity and pharmaceutical researches.
Journal ArticleDOI
Recent updates on immunological, pharmacological, and alternative approaches to combat COVID-19.
TL;DR: In this article, the authors provide an update on the efficacy and safety of the repurposed, and natural drugs to treat COVID-19 as well as the vaccines used for its prophylaxis.
Journal ArticleDOI
Andrographolide: A Herbal-Chemosynthetic Approach for Enhancing Immunity, Combating Viral Infections, and Its Implication on Human Health.
TL;DR: In this article, the authors have discussed the possible role of AGL as a promising herbal-chemo remedy during human diseases, viral infections and as an immunity booster, which is known for its immunostimulant activity against a variety of microbial infections thereby regulating classical and alternative macrophage activation, Ag-specific antibody production during immune disorder therapy.
Journal ArticleDOI
Molecular encapsulation of andrographolide in 2-hydroxypropyl-β-cyclodextrin cavity: synthesis, characterization, pharmacokinetic and in vitro antiviral activity analysis against SARS-CoV-2.
Shashi Chandrama Singh,Dharmendra Kumar Khatri,Kulbhaskar Singh,Vinay Kumar Kanchupalli,Jitender Madan,Shashi Bala Singh,Harshpal Singh +6 more
TL;DR: In this paper, Andrographolide-2-hydroxypropyl-β-cyclodextrin (AND) was synthesized and characterized for antiviral and pharmacokinetic profile.
References
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Journal ArticleDOI
Polysaccharide Encrusted Multilayered Nano-Colloidal System of Andrographolide for Improved Hepatoprotection
TL;DR: The in vivo study exhibited the significantly improved hepatoprotection by andrographolide when delivered in stable multi-layered NE carrier systems, which assured the increased availability in simulated biological fluids.
Journal ArticleDOI
Andrographis paniculata extracts and major constituent diterpenoids inhibit growth of intrahepatic cholangiocarcinoma cells by inducing cell cycle arrest and apoptosis.
Tawit Suriyo,Nanthanit Pholphana,Nuchanart Rangkadilok,Nuchanart Rangkadilok,Apinya Thiantanawat,Apinya Thiantanawat,Piyajit Watcharasit,Piyajit Watcharasit,Jutamaad Satayavivad,Jutamaad Satayavivad,Jutamaad Satayavivad +10 more
TL;DR: Andrographis paniculata could be a promising herbal plant for the alternative treatment of intrahepatic cholangiocarcinoma because of its potent cytotoxic activity against the growth of liver and bile duct cancer cells.
Journal ArticleDOI
Solubility of Andrographolide in Various Solvents from (288.2 to 323.2) K
TL;DR: In this paper, the solubilities of andrographolide in methanol, ethanol, butan-1-ol, propanone, and water over the temperature range of (288.2 to 323.2) K were measured.
Journal ArticleDOI
[Corrigendum] Inhibition of MDA-MB-231 breast cancer cell migration and invasion activity by andrographolide via suppression of nuclear factor-κB-dependent matrix metalloproteinase-9 expression.
Zanjing Zhai,Xinhua Qu,Haowei Li,Zhengxiao Ouyang,Wei Yan,Guangwang Liu,Xuqiang Liu,Qiming Fan,Tingting Tang,Kerong Dai,An Qin +10 more
TL;DR: The image selected to represent the experiment showing the migration of cells in the presence of andrographolide (30 μM) was chosen incorrectly during the figure compilation process.
Journal ArticleDOI
Andrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway
TL;DR: The pretreatment of U937 with andrographolide followed by low doses of TP showed an enhancement in inducing apoptosis when compared to the application of each compound separately.