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Aspiration thrombectomy versus stent retriever thrombectomy as first-line approach for large vessel occlusion (COMPASS): a multicentre, randomised, open label, blinded outcome, non-inferiority trial

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TLDR
This study supports the use of direct aspiration as an alternative to stent retriever as first-line therapy for stroke thrombectomy and assesses whether patients treated with aspiration as first pass have non-inferior functional outcomes to those treated with a stent retrievers as first line.
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This article is published in The Lancet.The article was published on 2019-03-09. It has received 265 citations till now. The article focuses on the topics: Modified Rankin Scale.

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Journal ArticleDOI

Management of acute ischemic stroke

TL;DR: The data supporting pre-hospital and emergency stroke care, including use of emergency medical services protocols for identification of patients with stroke, intravenous thrombolysis in acute ischemic stroke, and recent updates in secondary prevention recommendations are reviewed.
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Clot-Based Radiomics Predict a Mechanical Thrombectomy Strategy for Successful Recanalization in Acute Ischemic Stroke.

TL;DR: Clot-based radiomics have the ability to predict an MTB strategy for successful recanalization in acute ischemic stroke, thus allowing a potentially better selection of theMTB strategy, as well as patients who are most likely to benefit from the intervention.
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Direct thromboaspiration efficacy for mechanical thrombectomy is related to the angle of interaction between the aspiration catheter and the clot.

TL;DR: An angle of interaction between the aspiration catheter and the clot of ≥125.5° was significantly associated with successful clot removal and the prediction of the angle of interacting on pretreatment imaging may help operators to select the most adequate mechanical thrombectomy technique on a case by case basis.
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Optimizing fast first pass complete reperfusion in acute ischemic stroke - the BADDASS approach (BAlloon guiDe with large bore Distal Access catheter with dual aspiration with Stent-retriever as Standard approach)

TL;DR: The purpose of this review is to enable neurointerventionalists to achieve fast first pass complete reperfusion by outlining the BADDASS approach step-by-step and sharing additional tips for navigating through challenging internal carotid artery segments.
References
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Guidelines for the Early Management of Patients With Acute Ischemic Stroke A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

TL;DR: These guidelines supersede the prior 2007 guidelines and 2009 updates and support the overarching concept of stroke systems of care and detail aspects of stroke care from patient recognition; emergency medical services activation, transport, and triage; through the initial hours in the emergency department and stroke unit.
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A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke

TL;DR: In patients with acute ischemic stroke caused by a proximal intracranial occlusion of the anterior circulation, intraarterial treatment administered within 6 hours after stroke onset was effective and safe.
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Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection

TL;DR: In patients with ischemic stroke with a proximal cerebral arterial occlusion and salvageable tissue on CT perfusion imaging, early thrombectomy with the Solitaire FR stent retriever, as compared with alteplase alone, improved reperfusion, early neurologic recovery, and functional outcome.
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