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BioCreAtIvE Task 1A: gene mention finding evaluation

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TLDR
The 80% plus F-measure results are good, but still somewhat lag the best scores achieved in some other domains such as newswire, due in part to the complexity and length of gene names, compared to person or organization names in newswire.
Abstract
The biological research literature is a major repository of knowledge. As the amount of literature increases, it will get harder to find the information of interest on a particular topic. There has been an increasing amount of work on text mining this literature, but comparing this work is hard because of a lack of standards for making comparisons. To address this, we worked with colleagues at the Protein Design Group, CNB-CSIC, Madrid to develop BioCreAtIvE (Critical Assessment for Information Extraction in Biology), an open common evaluation of systems on a number of biological text mining tasks. We report here on task 1A, which deals with finding mentions of genes and related entities in text. "Finding mentions" is a basic task, which can be used as a building block for other text mining tasks. The task makes use of data and evaluation software provided by the (US) National Center for Biotechnology Information (NCBI). 15 teams took part in task 1A. A number of teams achieved scores over 80% F-measure (balanced precision and recall). The teams that tried to use their task 1A systems to help on other BioCreAtIvE tasks reported mixed results. The 80% plus F-measure results are good, but still somewhat lag the best scores achieved in some other domains such as newswire, due in part to the complexity and length of gene names, compared to person or organization names in newswire.

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Proceedings ArticleDOI

An Analysis of Active Learning Strategies for Sequence Labeling Tasks

TL;DR: This paper surveys previously used query selection strategies for sequence models, and proposes several novel algorithms to address their shortcomings, and conducts a large-scale empirical comparison.
Journal ArticleDOI

Overview of BioCreAtIvE: critical assessment of information extraction for biology

TL;DR: The first BioCreAtIvE assessment provided state-of-the-art performance results for a basic task (gene name finding and normalization), where the best systems achieved a balanced 80% precision / recall or better, which potentially makes them suitable for real applications in biology.
Proceedings ArticleDOI

BANNER: an executable survey of advances in biomedical named entity recognition.

TL;DR: BANNER is an open-source, executable survey of advances in biomedical named entity recognition, intended to serve as a benchmark for the field and is designed to maximize domain independence by not employing brittle semantic features or rule-based processing steps.
Journal ArticleDOI

The CHEMDNER corpus of chemicals and drugs and its annotation principles.

Martin Krallinger, +52 more
TL;DR: The CHEMDNER corpus is presented, a collection of 10,000 PubMed abstracts that contain a total of 84,355 chemical entity mentions labeled manually by expert chemistry literature curators, following annotation guidelines specifically defined for this task.
References
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Proceedings Article

Transductive Inference for Text Classification using Support Vector Machines

TL;DR: An analysis of why Transductive Support Vector Machines are well suited for text classi cation is presented, and an algorithm for training TSVMs, handling 10,000 examples and more is proposed.
Book

Computer-intensive methods for testing hypotheses : an introduction

TL;DR: Approximate Randomization Tests.
Proceedings ArticleDOI

More accurate tests for the statistical significance of result differences

TL;DR: It is found in a set of experiments that many commonly used tests often underestimate the significance and so are less likely to detect differences that exist between different techniques, including computationally-intensive randomization tests.
Journal ArticleDOI

Accomplishments and challenges in literature data mining for biology

TL;DR: To encourage participation and accelerate progress in this expanding field of literature data mining, it is proposed creating challenge evaluations, and two specific applications are described in this context.
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