Journal ArticleDOI
Biologic function of the Fc fragments of E myeloma protein
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The results suggested that structural changes in the Fc portion of γE molecules initiate enzymatic sequences leading to the release of the chemical mediators in E myeloma protein PS.About:
This article is published in Immunochemistry.The article was published on 1970-08-01. It has received 146 citations till now. The article focuses on the topics: Fragment crystallizable region & Papain.read more
Citations
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Journal ArticleDOI
The structure of immunoglobulins and their genes, DNA rearrangement and B cell differentiation, molecular anomalies of some monoclonal immunoglobulins.
Journal ArticleDOI
On-line coupling of surface plasmon resonance optical sensing to size-exclusion chromatography for affinity assessment of antibody samples
TL;DR: Coupled size-exclusion chromatography (SEC) SPR sensing for the separation of sample components prior to their on-line bio-interaction analysis allows specific label-free analysis of real-time interactions of eluting antibody sample constituents towards their antigenic target.
Journal ArticleDOI
Measurement of the potency of pollen extract by radioimmunoprecipitation
TL;DR: The RIP procedure provides an alternative to the RAST for the standardization of allergy extracts and eliminates the need for affinity chromatography-purified antibody to IgE.
Book ChapterDOI
Biochemistry and Biology of Complement Activation
W. Opferkuch,M. Segerling +1 more
TL;DR: The complement system may be considered as the effector and amplification system of the humoral immune reaction, which is the trigger of a biological reaction mediated by the complement system.
Book ChapterDOI
Stimulus-Secretion Coupling in Mast Cells and Basophils
TL;DR: The mechanism whereby a very small stimulus acting at the cell periphery is translated into the fusion of granules with each other and the plasma membrane with the resulting secretion of mediators is termed stimulus-secretion coupling.
References
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Journal ArticleDOI
Immunochemical quantitation of antigens by single radial immunodiffusion
TL;DR: By standardizing the technical conditions of the experiment it is possible to use this principle for the immunochemical determination of antigens, and the lower limit of the method was found to correspond to 0·0025 μg of antigen, and to an antigen concentrations of 1·25 μg per ml.
Journal ArticleDOI
Estimation of the molecular weights of proteins by Sephadex gel-filtration.
TL;DR: The results are similar to those of previous studies, where the objective was to establish a cause-and-effect relationship, rather than a straightforward relationship between the number of cells and the content of the molecule.
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