Journal ArticleDOI
Biologic function of the Fc fragments of E myeloma protein
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TLDR
The results suggested that structural changes in the Fc portion of γE molecules initiate enzymatic sequences leading to the release of the chemical mediators in E myeloma protein PS.About:
This article is published in Immunochemistry.The article was published on 1970-08-01. It has received 146 citations till now. The article focuses on the topics: Fragment crystallizable region & Papain.read more
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Book ChapterDOI
3 – Human Immunoglobulins
TL;DR: This chapter describes some of the general structural features and properties of the various classes of human immunoglobulin, particularly the enzymes papain and pepsin.
Journal ArticleDOI
Mouse monoclonal antibodies at the red cell surface—I. Generation of EAC4 and interaction with C1
TL;DR: The ability of monoclonal antibodies in the EAC4 complex to bind C1 and to detect C1 activity is not significantly different from that of polyclonal antibodies but that monoconal antibodies are less efficient in activating C1 than polyclonic antibodies.
Book ChapterDOI
Chapter 25. Early Biochemical Events Leading to Mast Cell and Basophil Degranulation
TL;DR: It is demonstrated that a number of unique biochemical reactions are responsible for IgE-mediated mast cell degranulation, and that the reagents and suitable as says and screens are now available for the development of specific and novel anti-allergic drugs.
Journal ArticleDOI
Fonction des immunoglobulines E(
J.P. Girard,M. Cuevas +1 more
TL;DR: Les IgE repr4sentent une elasse distincte d'immunoglobulines qui jouent un r61e important darts les maladies atopiques et certaines infections parasitaires, ainsi que eertains fact:curs qui modulent la rdgulation de sa synthbse.
References
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Journal ArticleDOI
Immunochemical quantitation of antigens by single radial immunodiffusion
TL;DR: By standardizing the technical conditions of the experiment it is possible to use this principle for the immunochemical determination of antigens, and the lower limit of the method was found to correspond to 0·0025 μg of antigen, and to an antigen concentrations of 1·25 μg per ml.
Journal ArticleDOI
Estimation of the molecular weights of proteins by Sephadex gel-filtration.
TL;DR: The results are similar to those of previous studies, where the objective was to establish a cause-and-effect relationship, rather than a straightforward relationship between the number of cells and the content of the molecule.
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