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Biological Regulation and Development

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The article was published on 1979-01-01. It has received 495 citations till now. The article focuses on the topics: Biological regulation.

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Selfish genes, the phenotype paradigm and genome evolution.

TL;DR: Natural selection operating within genomes will inevitably result in the appearance of DNAs with no phenotypic expression whose only ‘function’ is survival within genomes.
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The maternal-to-zygotic transition: a play in two acts

TL;DR: The maternal-to-zygotic transition (MZT) has been extensively studied in model organisms, including echinoderms, nematodes, insects, fish, amphibians and mammals.
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The long and the short of long–term memory—a molecular framework

TL;DR: A single learning event initiates several memory processes with different time courses of retention, and the finding that long-term memory requires the expression, during learing, of additional genes makes it possible to analyse in molecular terms the induction and retention of long- term memory.
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Information content of binding sites on nucleotide sequences

TL;DR: Comparisons between R sequence and R frequency suggest that the information at binding sites is just sufficient for the sites to be distinguished from the rest of the genome.
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Preferential codon usage in prokaryotic genes: the optimal codon-anticodon interaction energy and the selective codon usage in efficiently expressed genes.

TL;DR: It is hypothesized that both the optimization of codon-anticodon interaction energy and the adaptation of the population to codon frequency or vice versa in highly expressed mRNAs of E. coli are part of a strategy that optimizes the efficiency of translation.
References
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Current concepts of the immunological function of the thymus.

TL;DR: Discriminant spleen assays performed in thymectomized mice recieved negative results on the basis of EMT or “cell reprograming,” respectively.
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Growth-hormone release-inhibiting hormone in gastrointestinal and pancreatic d cells

TL;DR: Combined immunocytochemical methods, and histological methods for endocrine granules, have demonstrated that the normal pancreatic D cell contains a product with G.I.H.H-like immunoreactivity, which suggests that it may play an important role in digestive physiology.
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Intestinal Factors in the Control of Insulin Secretion

TL;DR: Results obtained in 2 patients with cirrhosis of the liver who had had end-to-side portacaval shunts performed led to an exaggeration of the inverse relationship between the blood glucose and plasma insulin levels.
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The preparation, identification and assay of prolactin—a hormone of the anterior pituitary

TL;DR: Though lactation in certain species has sometimes been observed, these cases are probably of importance only to a further elucidation of a, species variability; b, a final preparatory stage of mammary tissue development; c, and of the mechanism by which the anterior pituitary is induced to release the principle which excites milk secretion.
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