Journal ArticleDOI
Birth and differentiation of reticular neurons in the chick hindbrain: Ontogeny of the first neuronal population
TLDR
The results suggest that the inductive cues governing the birth and initial differentiation of reticular neurons are imparted by gastrulation and early neurulation.About:
This article is published in Neuron.The article was published on 1991-12-01. It has received 66 citations till now. The article focuses on the topics: Reticular formation & Reticular connective tissue.read more
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Expression of a Delta homologue in prospective neurons in the chick
TL;DR: It is shown that C-Delta-1 is expressed in prospective neurons during neurogenesis, as new cells are being born and their fates decided, suggesting that both the Delta/ Notch signalling mechanism and its role in Neurogenesis have been conserved in vertebrates.
Journal ArticleDOI
Conservation of the Notch signalling pathway in mammalian neurogenesis
J.L. Pompa de la,Andrew Wakeham,K.M. Correia,Enrique Samper,S. Brown,Renato J. Aguilera,Toru Nakano,Tasuku Honjo,Tak W. Mak,J. Rossant,Ronald A. Conlon +10 more
TL;DR: Conservation of the Notch pathway and its regulatory mechanisms from fly to mouse are demonstrated, and a role for the murine Notch signalling pathway in the regulation of neural stem cell differentiation is supported.
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Opposing FGF and Retinoid Pathways Control Ventral Neural Pattern, Neuronal Differentiation, and Segmentation during Body Axis Extension
Ruth Diez del Corral,Isabel Olivera-Martinez,Anne Goriely,Emily Gale,Malcolm Maden,Kate G. Storey +5 more
TL;DR: The data demonstrate that FGF and RA pathways are mutually inhibitory and suggest that their opposing actions provide a global mechanism that controls differentiation during axis extension.
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Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate.
TL;DR: The identity and patterning of neural cell types appear to involve distinct contact-mediated and diffusible signals from the notochord and floor plate.
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Fate of midbrain dopaminergic neurons controlled by the engrailed genes.
TL;DR: Findings show that the engrailed genes are expressed by midbrain dopaminergic neurons from their generation to adulthood but are not required for their specification, and suggest a link between En-1 and En-2 and Parkinson's disease.
References
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THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY
TL;DR: The stain reported here differs from previous alkaline lead stains in that the chelating agent, citrate, is in sufficient excess to sequester all lead present, and is less likely to contaminate sections.
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A series of normal stages in the development of the chick embryo
TL;DR: The preparation of a series of normal stages of the chick embryo does not need justification at a time when chick ernbryos are not only widely used in descriptive and experimental embryology but are proving to be increasingly valuable in medical research, as in work on viruses and cancer.
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Staining of Tissue Sections for Electron Microscopy with Heavy Metals
TL;DR: Certain hitherto unobserved details are revealed and some sort of specificity exists, although the factors involved are not yet understood.
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Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication
TL;DR: Monoclonal antibodies specific for 5-bromodeoxyuridine have been produced and applied in detecting low levels of DNA replication on a cell-by-cell basis in vitro and do not cross-react with thymidine.